γ-Glutamyl transpeptidase catalyses the extracellular detoxification of cisplatin in a human cell line derived from the proximal convoluted tubule of the kidney

European Journal of Cancer

Volumn 39, Issue 7, 2003, Pages 996-1003

  Paolicchi, A ^a   Sotiropuolou, M ^b   Perego, P ^c   Daubeuf, S ^d   Visvikis, A ^e   Lorenzini, E ^a   Franzini, M ^a   Romiti, N ^a   Chieli, E ^a   Leone, R ^c   Apostoli, P ^f   Colangelo, D ^g   Zunino, F ^c   Pompella, A ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF IOANNINA   (Greece)

^c Pediatric Oncology Unit   (Italy)

^d UNIVERSITÉ DE LORRAINE   (France)

^e UNIVERSITY OF VERONA   (Italy)

^f UNIVERSITY OF BRESCIA   (Italy)

^g UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

Cisplatin; Kidney tubular cells; Toxicity; Glutamyl transpeptidase

Indexed keywords

CISPLATIN; CYSTEINYLGLYCINE; DIPEPTIDE DERIVATIVE; DNA; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLYCYLGLYCINE; PLATINUM; THIOL DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CATALYSIS; CELL IMMORTALIZATION; CELL LEVEL; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DETOXIFICATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME METABOLISM; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MODULATION; NEPHROTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0347298783     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(03)00067-4     Document Type: Article

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