β-lyase-dependent attenuation of cisplatin-mediated toxicity by selenocysteine Se-conjugates in renal tubular cell lines

Journal of Pharmacology and Experimental Therapeutics

Volumn 301, Issue 3, 2002, Pages 884-892

  Rooseboom, Martijn ^a,b   Schaaf, Gerben ^a,b   Commandeur, Jan N M ^a   Vermeulen, Nico P E ^a   Fink Gremmels, Johanna ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BETA LYASE; CISPLATIN; COMPLEMENTARY DNA; DICHLORODIHYDROFLUORESCEIN DIACETATE; FLUORESCENT DYE; GLUTAMINE PHENYLPYRUVATE AMINOTRANSFERASE; LYASE; NEUTRAL RED; PROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; SE METHYLSELENOCYSTEINE; SELENIUM (2 CHLOROBENZYL)SELENOCYSTEINE; SELENIUM (2 METHOXYPHENYL)SELENOCYSTEINE; SELENIUM DERIVATIVE; SELENOCYSTEINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL PROTECTION; CELL STRAIN; CONTROLLED STUDY; DRUG ACTIVATION; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SELECTIVITY; DRUG UPTAKE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KIDNEY TUBULE CELL; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STAINING;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE; CELL SURVIVAL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY TUBULES, PROXIMAL; LLC-PK1 CELLS; LYASES; RATS; REACTIVE OXYGEN SPECIES; SELENIUM; SELENOCYSTEINE; SWINE;

EID: 0036260757     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.301.3.884     Document Type: Article

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