Transfection of NS0 myeloma fusion partner cells with hsp70 gene results in higher hybridoma yield by improving cellular resistance to apoptosis

Biotechnology and Bioengineering

Volumn 81, Issue 4, 2003, Pages 496-504

  Lasunskaia, Elena B ^a   Fridlianskaia, Irina I ^b   Darieva, Zoulfia A ^a   Da Silva, Mariele S R ^a   Kanashiro, Milton M ^a   Margulis, Boris A ^b  

^a UNIVERSIDADE ESTADUAL DO NORTE FLUMINENSE DARCY RIBEIRO   (Brazil)

^b INSTITUTE OF CYTOLOGY   (Russian Federation)

Author keywords

Apoptosis; Cell culture; Hsp70; Hybridoma; Myeloma

Indexed keywords

BATCH CELL CULTURE; DNA; GENETIC ENGINEERING; NUTRITION;

MYELOMA CELLS; TRANSFECTION;

MONOCLONAL ANTIBODIES;

BETA ACTIN; CASPASE 3; DNA FRAGMENT; HEAT SHOCK PROTEIN 70; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANTIBODY PRODUCTION; APOPTOSIS; ARTICLE; CELL FUSION; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE FUSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYBRIDOMA; MOUSE; MYELOMA CELL; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; SPLEEN CELL;

ANIMALS; APOPTOSIS; CELL COUNT; CELL SURVIVAL; CLONING, MOLECULAR; FEMALE; GENE EXPRESSION REGULATION; HSP70 HEAT-SHOCK PROTEINS; HUMANS; HYBRIDOMAS; MICE; MICE, INBRED BALB C; MULTIPLE MYELOMA; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED; U937 CELLS;

EID: 0347297482     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10493     Document Type: Article

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