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Volumn 25, Issue 1-3, 1997, Pages 17-23

Anti-apoptotic genes, bag-1 and bcl-2, enabled hybridoma cells to survive under treatment for arresting cell cycle

Author keywords

Anti apoptotic; bag 1; bcl 2; Cell cycle arrest; Excess thymidine; Serum limitation

Indexed keywords


EID: 0031426193     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1007954103572     Document Type: Article
Times cited : (31)

References (30)
  • 1
    • 2642698421 scopus 로고
    • Flow cytometric studies during synchronous and asynchronous suspension cultures of hybridoma cells
    • Spier RE, Griffiths HB, Stephenne J and Crooy PJ (eds.). Butterworths, Kent
    • Al-Reubeai M, Rookes and Emery An (1989) Flow cytometric studies during synchronous and asynchronous suspension cultures of hybridoma cells. In: Spier RE, Griffiths HB, Stephenne J and Crooy PJ (eds.). Advances in animal cell biology and technology for bioprocesses (pp. 241-245) Butterworths, Kent.
    • (1989) Advances in Animal Cell Biology and Technology for Bioprocesses , pp. 241-245
    • Al-Reubeai, M.1    Rookes2    Emery, An.3
  • 3
    • 0014692683 scopus 로고
    • Limited periods of gene expression in immunoglobulin-synthesizing cells
    • Bueall DN and Fahey JL (1969) Limited periods of gene expression in immunoglobulin-synthesizing cells. Science 164: 1524-1525.
    • (1969) Science , vol.164 , pp. 1524-1525
    • Bueall, D.N.1    Fahey, J.L.2
  • 4
    • 0014951567 scopus 로고
    • Programmed synthesis and export of immunoglobulin by synchronized myeloma cells
    • Byars N and Kisdon C (1970) Programmed synthesis and export of immunoglobulin by synchronized myeloma cells. Nature 226: 648-650.
    • (1970) Nature , vol.226 , pp. 648-650
    • Byars, N.1    Kisdon, C.2
  • 5
    • 0018848094 scopus 로고
    • Enzyme immunoassay ELISA and EMIT
    • Van Vunakis H and Langone JJ (ed.) Acedemic Press, New York
    • Engvall E (1980) Enzyme immunoassay ELISA and EMIT. In: Van Vunakis H and Langone JJ (ed.) Methods in Enzymology. Vol. 70 (pp. 419-439) Acedemic Press, New York.
    • (1980) Methods in Enzymology , vol.70 , pp. 419-439
    • Engvall, E.1
  • 6
    • 0017226698 scopus 로고
    • Synthesis and secretion of light-chain immunoglobulin in two successive cycles of synchronized plasmacytoma cells
    • Garatun-Tjeldstø O, Pryme IF, Weltman JK and Dowben RM (1971) Synthesis and secretion of light-chain immunoglobulin in two successive cycles of synchronized plasmacytoma cells. J. Cell Biol. 68: 232-239.
    • (1971) J. Cell Biol. , vol.68 , pp. 232-239
    • Garatun-Tjeldstø, O.1    Pryme, I.F.2    Weltman, J.K.3    Dowben, R.M.4
  • 7
    • 0029048389 scopus 로고
    • Overexpression of bcl-2, apoptosis suppressing gene: Prolonged viable culture period of hydridoma and enhanced antibody production
    • Itoh Y, Udea H and Suzuki E(1995) Overexpression of bcl-2, apoptosis suppressing gene: prolonged viable culture period of hydridoma and enhanced antibody production. Biotechnol. Bioeng. 48: 118-122.
    • (1995) Biotechnol. Bioeng. , vol.48 , pp. 118-122
    • Itoh, Y.1    Udea, H.2    Suzuki, E.3
  • 8
    • 0002298102 scopus 로고
    • The synchronization of mammalian cells
    • Fantes P and Brooks R (ed.) IRL Press, Oxford
    • Johnson RT, Downes CS and Meyn RE (1993) The synchronization of mammalian cells. In: Fantes P and Brooks R (ed.) The cell cycle a practical approach, (pp. 1-22) IRL Press, Oxford.
    • (1993) The Cell Cycle a Practical Approach , pp. 1-22
    • Johnson, R.T.1    Downes, C.S.2    Meyn, R.E.3
  • 9
    • 0025193047 scopus 로고
    • 5 pre-B cell-specific genes can associate with each other and with m heavy chain
    • 5 pre-B cell-specific genes can associate with each other and with m heavy chain. J. Exp. Med. 172: 969-972.
    • (1990) J. Exp. Med. , vol.172 , pp. 969-972
    • Karasuyama, H.1    Kudo, A.2    Melchers, F.3
  • 10
    • 0027012758 scopus 로고
    • Interleukin-6 is antiproliferative to a mouse hybridoma cell line and promotive for its antibody productivity
    • Makishima F, Terada S, Mikami T and Susuki E (1992) Interleukin-6 is antiproliferative to a mouse hybridoma cell line and promotive for its antibody productivity. Cytotechnology 10: 15-23.
    • (1992) Cytotechnology , vol.10 , pp. 15-23
    • Makishima, F.1    Terada, S.2    Mikami, T.3    Susuki, E.4
  • 11
    • 0028765762 scopus 로고
    • Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells
    • Mercille S and Massie B (1994) Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells. Biotechnol. Bioeng. 44: 1140-1154.
    • (1994) Biotechnol. Bioeng. , vol.44 , pp. 1140-1154
    • Mercille, S.1    Massie, B.2
  • 12
    • 0026781986 scopus 로고
    • bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cell to cell death and DNA fragmentation induced by glucocorticoids and multiple chemitherapeutic drugs
    • MiyashitaT and Reed JC (1992) bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cell to cell death and DNA fragmentation induced by glucocorticoids and multiple chemitherapeutic drugs. Cancer Research 52: 5407-5411.
    • (1992) Cancer Research , vol.52 , pp. 5407-5411
    • Miyashita, T.1    Reed, J.C.2
  • 13
    • 0025255538 scopus 로고
    • Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived haempoietic cell lines
    • Nunez G, London L, Hockenberry D, Alexander M, McKearn JP and Korshmeyer H (1990) Deregulated bcl-2 gene expression selectively prolongs survival of growth factor-deprived haempoietic cell lines. J. Immunol. 144: 3692-3610.
    • (1990) J. Immunol. , vol.144 , pp. 3692-13610
    • Nunez, G.1    London, L.2    Hockenberry, D.3    Alexander, M.4    McKearn, J.P.5    Korshmeyer, H.6
  • 15
    • 0016358092 scopus 로고
    • The stimulation of light chain immunoglobulin synthesis in vitro by 0.5 M salt wash of MPC-11 membrane-bound polysomes isolated in the G1 and G2 phases of the cell cycle
    • Pryme IF (1974) The stimulation of light chain immunoglobulin synthesis in vitro by 0.5 M salt wash of MPC-11 membrane-bound polysomes isolated in the G1 and G2 phases of the cell cycle. Biochem. Biophys. Res. Commun. 61: 838-844.
    • (1974) Biochem. Biophys. Res. Commun. , vol.61 , pp. 838-844
    • Pryme, I.F.1
  • 16
    • 0025499794 scopus 로고
    • Cell cycle- and growth phase-dependent variations in size distribution, antibody productivity, and oxyhen demand in hybridoma cultures
    • Ramirez OT and Mutharasan R (1990) Cell cycle- and growth phase-dependent variations in size distribution, antibody productivity, and oxyhen demand in hybridoma cultures. Biotechnol. Bioeng. 36: 839-848.
    • (1990) Biotechnol. Bioeng. , vol.36 , pp. 839-848
    • Ramirez, O.T.1    Mutharasan, R.2
  • 17
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed JC (1994) Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124: 1-6.
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 19
    • 0015293356 scopus 로고
    • The synthesis of acidic chromosomal proteins during the cell cycle of HeLa S3 cells
    • Stein GS and Borun TE (1972) The synthesis of acidic chromosomal proteins during the cell cycle of HeLa S3 cells J. Cell Biol. 52: 292-307.
    • (1972) J. Cell Biol. , vol.52 , pp. 292-307
    • Stein, G.S.1    Borun, T.E.2
  • 20
    • 0025428793 scopus 로고
    • Enhanced antibody production at slowed growth rates: Experimental demonstration and a simple structure model
    • Suzuki E and Ollis DF (1990) Enhanced antibody production at slowed growth rates: experimental demonstration and a simple structure model. Biotechnol. Prog. 6: 231-236.
    • (1990) Biotechnol. Prog. , vol.6 , pp. 231-236
    • Suzuki, E.1    Ollis, D.F.2
  • 21
    • 0007769719 scopus 로고
    • A simple structured model predicted positively-, negatively-, or non-growth associated antibody productionn rate depending on culture condition
    • Murakami H, Shirahata S and Tachibana H (ed.) Kluwer Academic Publisher, Dordrecht
    • Suzuki E, Takahashi K and Ollis DF (1992) A simple structured model predicted positively-, negatively-, or non-growth associated antibody productionn rate depending on culture condition. In: Murakami H, Shirahata S and Tachibana H (ed.) Animal cell technology:basic and applied aspects, Vol. 4, (pp. 15-21) Kluwer Academic Publisher, Dordrecht.
    • (1992) Animal Cell Technology:basic and Applied Aspects , vol.4 , pp. 15-21
    • Suzuki, E.1    Takahashi, K.2    Ollis, D.F.3
  • 22
    • 0028711950 scopus 로고
    • Growth rate suppression of cultured mammalian cells enhances protein productivity
    • Takahashi K, Terada S, Ueda H, Makishima F and Suzuki E (1994) Growth rate suppression of cultured mammalian cells enhances protein productivity. Cytotechnology 15: 54-64.
    • (1994) Cytotechnology , vol.15 , pp. 54-64
    • Takahashi, K.1    Terada, S.2    Ueda, H.3    Makishima, F.4    Suzuki, E.5
  • 23
    • 0014593345 scopus 로고
    • Immunoglobulin production in synchronized cultures of human hematopoietic cell lines
    • Takahashi M, Yagi Y, Moore GE and Pressman D (1969) Immunoglobulin production in synchronized cultures of human hematopoietic cell lines. J. Immin. 103, 834-843.
    • (1969) J. Immin. , vol.103 , pp. 834-843
    • Takahashi, M.1    Yagi, Y.2    Moore, G.E.3    Pressman, D.4
  • 24
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2 binding protein with anti-cell death activity
    • Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA and Reed JC (1995) Cloning and functional analysis of BAG-1: a novel Bcl-2 binding protein with anti-cell death activity, cell 80: 279-284.
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 25
  • 26
    • 0001645533 scopus 로고
    • Growth and nucleic acid synthesis in synchronously dividing populations of HeLa cell
    • Terashima T and Tolmach JJ (1963) Growth and nucleic acid synthesis in synchronously dividing populations of HeLa cell. Exp. Cell Res. 30: 344-362.
    • (1963) Exp. Cell Res. , vol.30 , pp. 344-362
    • Terashima, T.1    Tolmach, J.J.2
  • 27
    • 0024454762 scopus 로고
    • Stress-resistance conferred by high level of Bcl-2a protein in human B lymphoblastoid cell
    • Tsujimoto Y (1989) Stress-resistance conferred by high level of Bcl-2a protein in human B lymphoblastoid cell. Oncogene 4: 1331-1336.
    • (1989) Oncogene , vol.4 , pp. 1331-1336
    • Tsujimoto, Y.1
  • 28
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalise pre-B cells
    • Vaux DL, Cory and Adams JM (1988) Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalise pre-B cells. Nature 335: 440-442.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory2    Adams, J.M.3
  • 29
    • 0029937303 scopus 로고    scopus 로고
    • Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1
    • Wang H-G, Takayama S, Rapp UR and Reed JC (1996) Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. Proc. Natl. Acad. Sci. USA. 93: 7063-7068.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7063-7068
    • Wang, H.-G.1    Takayama, S.2    Rapp, U.R.3    Reed, J.C.4
  • 30
    • 0021855166 scopus 로고
    • Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells
    • Zetterburg A and Larson O (1985) Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc. Natl. Acad. Sci. USA 82: 5365-53699.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 5365-53699
    • Zetterburg, A.1    Larson, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.