Substrate specificity of CDK2-cyclin A: What is optimal?

Journal of Biological Chemistry

Volumn 278, Issue 51, 2003, Pages 50956-50960

  Stevenson Lindert, Lisa M ^a,b   Fowler, Paul ^a   Lew, John ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CALIFORNIA POLYTECHNIC STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ORGANIC COMPOUNDS; PHYSIOLOGY; SUBSTRATES;

CATALYTIC EFFICIENCY; CHEMICAL PHOSPHOTRANSFER;

ENZYMES;

CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYCLIN E; LYSINE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CELL CYCLE G2 PHASE; COMPLEX FORMATION; DNA REPLICATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN MOTIF;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYSIS; CDC2-CDC28 KINASES; CONSENSUS SEQUENCE; CYCLIN A; CYCLIN-DEPENDENT KINASE 2; HUMANS; KINETICS; PHOSPHORYLATION; PROTEIN BINDING; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 0347065362     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M306546200     Document Type: Article

References (36)

1. Moreno, S., and Nurse, P. (1990) Cell 61, 549-551
2. Nigg, E. A. (1991) Semin. Cell Biol. 2, 261-270
3. Shenoy, S., Choi, J. K., Bagrodia, S., Copeland, T. D., Maller, J. L., and Shalloway, D. (1989) Cell 57, 763-774
4. Holmes, J. K., and Solomon, M. J. (1996) J. Biol. Chem. 271, 25240-25246
5. Beaudette, K. N., Lew, J., and Wang, J. H. (1993) J. Biol. Chem. 268, 20825-20830
6. Hagopian, J. C., Kirtley, M. P., Stevenson, L. M., Gergis, R. M., Russo, A. A., Pavletich, N. P., Parsons, S. M., and Lew, J. (2001) J. Biol. Chem. 276, 275-280
7. Songyang, Z., Blechner, S., Hoagland, N., Hoekstra, M. F., Piwnica-Worms, H., and Cantley, L. C. (1994) Curr. Biol. 4, 973-982
8. Harper, J. W., and Adams, P. D. (2001) Chem. Rev. 101, 2511-2526
9. Harbour, J. W., Luo, R. X., Dei Santi, A., Postigo, A. A., and Dean, D. C. (1999) Cell 98, 859-869
10. Muller, H., Bracken, A. P., Vernell, R., Moroni, M. C., Christians, F., Grassilli, E., Prosperini, E., Vigo, E., Oliner, J. D., and Helin, K. (2001) Genes Dev. 15, 267-285
11. Sherr, C. J., and Roberts, J. M. (1999) Genes Dev. 13, 1501-1512
12. Kelly, T. J., and Brown, G. W. (2000) Annu. Rev. Biochem. 69, 829-880
13. Adams, P. D., Li, X., Sellers, W. R., Baker, K. B., Leng, X., Harper, J. W., Taya, Y., and Kaelin, W. G., Jr. (1999) Mol. Cell Biol. 19, 1068-1080
14. Adams, P. D., Sellers, W. R., Sharma, S. K., Wu, A. D., Nalin, C. M., and Kaelin, W. G., Jr. (1996) Mol. Cell Biol. 16, 6623-6633
15. Takeda, D. Y., Wohlschlegel, J. A., and Dutta, A. (2001) J. Biol. Chem. 276, 1993-1997
16. Wohlschlegel, J. A., Dwyer, B. T., Takeda, D. Y., and Dutta, A. (2001) Mol. Cell Biol. 21, 4868-4874
17. Stevenson, L. M., Deal, M. S., Hagopian, J. C., and Lew, J. (2002) Biochemistry 41, 8528-8534
18. Prowse, C. N., Hagopian, J. C., Cobb, M. H., Ahn, N. G., and Lew, J. (2000) Biochemistry 39, 6258-6266
19. Brouwer, A. C., and Kirsch, J. F. (1982) Biochemistry 21, 1302-1307
20. Blacklow, S. C., Raines, R. T., Lim, W. A., Zamore, P. D., and Knowles, J. R. (1988) Biochemistry 27, 683-733
21. Lew, J. (2003) Biochemistry 42, 849-856
22. Adams, J. A., and Taylor, S. S. (1992) Biochemistry 31, 8516-8522
23. Adams, J. A. (2001) Chem. Rev. 101, 2271-2290
24. Walsh, D. A., Angelos, K. L., Van Patten, S. M., Glass, D. B., and Garetto L. P. (1990) in Peptides and Protein Phosphorylation (Kemp, B. E., ed) pp. 44-84, CRC Press, Boca Raton, FL
25. Canagarajah, B. J., Khokhlatchev, A., Cobb, M. H., and Goldsmith, E. J. (1997) Cell 90, 859-869
26. Brown, N. R., Noble, M. E. M., Endicott, J. A., and Johnson, L. N. (1999) Nat. Cell Biol. 1, 438-443
27. Srinivasan, J., Koszelak, M., Mendelow, M., Kwon, Y. G., and Lawrence, D. S. (1995) Biochem. J. 309, 927-931
28. Marshak, D. R., Vandenberg, M. T., Bac, Y. S., and Yu, I. J. (1991) J. Cell. Biochem. 45, 391-400
29. Holmes, J. K., and Solomon, M. J. (2001) Eur. J. Biochem. 268, 4647-4652
30. Leng, X., Noble, M., Adams, P. D., Qin, J., and Harper, J. W. (2002) Mol. Cell Biol. 22, 2242-2254
31. Fersht, A. R. (1999) Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding, W. H. Freeman and Co., New York
32. Guida, P., and Zhu, L. (1999) Biochem. Biophys. Res. Commun. 258, 596-604
33. Ferrell, J. E., Jr. (1996) Trends Biochem. Sci. 21, 460-466
34. Ewen, M. E., Faha, B., Harlow, E., and Livingston, D. M. (1992) Science 255, 85-87
35. Krek, W., Ewen, M. E., Shirodkar, S., Arany, Z., Kaelin, W. G., Jr., and Livingston, D. M. (1994) Cell 78, 161-172
36. Shirodkar, S., Ewen, M., DeCaprio, J. A., Morgan, J., Livingston, D. M., and Chittenden, T. (1992) Cell 68, 157-166