Effects of dl-praeruptorin A on nucleus factor-κB and tumor necrosis factor-α expression in ischemia-reperfusion hearts

Acta Pharmacologica Sinica

Volumn 25, Issue 1, 2004, Pages 35-40

  Wang, Chi ^a   Chang, Tian Hui ^a   Zhang, Xin Hua ^a   Wang, Huai Liang ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

dl praeruptorin A; Ischemia; Myocardial; Nucleus factor B; Reperfusion injury; Tumor necrosis factor

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CREATINE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; POTASSIUM CHANNEL STIMULATING AGENT; PRAERUPTORIN A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CYTOPLASM; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MICROSCOPY; NONHUMAN; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RAT; REPERFUSION INJURY;

ANIMALS; CARDIOTONIC AGENTS; CORONARY CIRCULATION; COUMARINS; CREATINE KINASE; DRUGS, CHINESE HERBAL; FEMALE; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NF-KAPPA B; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0347022980     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Sawa Y. Gene Therapy for myocardial protection. Circulation 1997; 96 (9 Suppl): II-285.
2. Edward MB, Timothy GC, Elzabeth NM. Treating myocardial ischemia-reperfusion injury by targeting endothelial cell transcription. Ann Thorac Surg 1999; 68: 1949-53.
3. Maulik N, Sasaki H, Addya S. Regulation of cardiomyocyte apoptosis by redox-sensive transcription factors. FEBS Lett 2000; 485: 7-12.
4. Nikolaos G, Frangogiannis, Keith A. Cytokines and the microcirculation in ischemia and reperfusion. J Mol Cell Cardial 1998; 30: 2567-76.
5. Baldwin AS Jr. The NF-κB and IκB protein: new discoveries and insights. J Annu Rev Immunol 1996; 14: 649-83.
6. Li CF, Ha TZ, Liu LP. Adenosin prevents activation of transcription factor NF-κB and enhances activator protein-1 binging activity in ischemic rat heart. Surgery 2000; 127: 161-9.
7. Finco TS, Baldwin AS. Mechanistic aspects of NF kappa B regulation: the emerging role of phosphorylation and proteolysis. Immunity 1995; 3: 263-72.
8. Maulik N, Sato M, Price BD. An essential role of NF-kappaB in tyrosine kinase sighaling of p38 MAP kinase regulation of myocardial adaptational ischemia. FEBS Lett 1998; 429: 365-9.
9. Rian C, Andrea L, Amy MM. p38 MAPK and NF-κB collabotate to induce interleukin-6 gene expression and release. J Biol Chem 2000; 275: 23814-24.
10. Kupatt C, HabazettI H, Goedecke A. Tumor necrosis factor-alpha contributes to ischemia-reperfusion-induced endothelial activetion in isolated hearts. Circ Res 1999; 84: 392-400.
11. Sakaguchi T, Sawa Y, Fukushima N. A novel strategy of decoy transfection against nuclear factor-kappaB in myocardial preservation. Ann Thorac Surg 2001; 71: 624-9.
12. Altavilla D, Deodato B, Campo GM. IRFI 042, a novel dual vitamin E-like antioxidant, improve activation of nuclear factor-kappaB and reduces the inflammatory response in myocardial ischemia-reperfusion injury. Cardiovasc Res 2000; 47: 515-28.
13. Squadrito F, Altavilla D, Squadrito G. Tacrolimus limits polymerphonuclear leucocyte accumulation and protects against myocardial ischaemia-reperfusion injury. J Mol Cell Cardial 2000; 32: 429-40.
14. 2+-current and action potential duration in single ventricular cells of guinea pig hearts. Jpn J Pharmacognosy 1993; 47: 279-82.
15. Li JM, Chang TH, Sun XD, Hao LY, Wang YP, Yu YF, et al. Effects of dl-praeruptorin A on calcium current in ventricular cells of guinea pig. Acta Pharmacol Sin 1994; 15: 525-7.
16. Hao LY, Li JM, Chang TH, Sun XD, Wang YP, Zhang KY, et al. Frequency-dependent block of calcium current by praeruptorin A in single ventricular cell of guinea pig. Chin J Pharmacol Toxicol 1996; 10: 17-20.
17. Wang LJ, Li JM, Chang TH, Hao LY, Wang YP, Zhang KY, et al. Effects of Pd-Ia on delayed outward potassium current in single ventricular myocyte of guinea pig. Chin J Pharmacol Toxicol 1995; 9: 192-5.
18. Chang TH, Liu XY, Zhang XH. Effects of dl-praeruptorin A on interleukin-6 level and Fas, bax, bcl-2 protein expression in ischemia-reperfusion myocardium. Acta Pharmacol Sin 2002; 23: 769-74.
19. Perry WLM. Pharmacological experiments on isolated preparation. Edinburgh London and New York: Churchill Livingstone; 1970. p116-9.
20. Guo PK, Li YL, Wu SG. Sandwich ELISA assay of NF-κB. Chin Pharmacol Bull 2000; 16: 227-8.
21. Chang TH, Adachi H, Mori N, Saito I, Okuyama T. Effects of a pyrano-coumarin compound isolated from a Chinese medicinal plant, on ischemic myocardial dysfunction in anesthetized dogs. Eur J Pharmacol 1994; 258: 77-84.
22. Tomoo K, Kiyoshi S, Masaatsu U. Calcium antagonistic action of a coumarin isolated from "Qian-Hu", a Chinese traditional medicine. J Pharm Pharmacol 1981; 33: 317-20.
23. Li CF, William B, Race LK. Early activation of transcription factor NF-κB during ischemia in perfused rat heart. Am J Physiol 1999; 276 (2 Pt 2): H543-52.
24. Bysani C, John ES, James TC, Gregory LF. Inhibition of nuclear factor κB attenuates proinflammatory cytokine and inducible nitric-oxide synthase expression in postischemic myocardium. Biochim Biophys Acta 1998; 1406: 91-106.
25. Goline P, Ragni M, Cirillo P. Effects of tissue factor induced by oxygen free radicals on coronary flow during reperfusion. Nat Med 1996; 2: 35-40.