IRFI 042, a novel dual vitamin E-like antioxidant, inhibits activation of nuclear factor-κB and reduces the inflammatory response in myocardial ischemia-reperfusion injury

Cardiovascular Research

Volumn 47, Issue 3, 2000, Pages 515-528

  Altavilla, Domenica ^a   Deodato, Barbara ^a   Campo, Giuseppe M ^a   Arlotta, Mariarita ^a   Miano, Maria ^a   Squadrito, Giovanni ^a   Saitta, Antonino ^a   Cucinotta, Domenico ^a   Ceccarelli, Stefano ^b   Ferlito, Marcella ^a   Tringali, Michelangelo ^a   Minutoli, Letteria ^a   Caputi, Achille P ^a   Squadrito, Francesco ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b Biomedica Foscama Research Center   (Italy)

Author keywords

Free radicals; Hemodynamics; Infection inflammation; Ischaemia; Necrosis; Reperfusion

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ELASTASE; FREE RADICAL; HYDROXYL RADICAL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; IRFI 042; MALONALDEHYDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEMODYNAMICS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIPID PEROXIDATION; MALE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; BENZOFURANS; CYTOPLASM; HYDROXYL RADICAL; I-KAPPA B PROTEINS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; LIPID PEROXIDATION; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NF-KAPPA B; OXIDATIVE STRESS; PANCREATIC ELASTASE; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SUPEROXIDE DISMUTASE; VITAMIN E;

EID: 0034683028     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(00)00124-3     Document Type: Article

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