Contribution of changes in ubiquitin and myelin basic protein to age-related cognitive decline

Neuroscience Research

Volumn 48, Issue 1, 2004, Pages 93-100

  Wang, Deng Shun ^a   Bennett, David A ^b   Mufson, Elliott J ^b   Mattila, Petri ^a   Cochran, Elizabeth ^b   Dickson, Dennis W ^a  

^a MAYO CLINIC   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Aging; Alzheimer's disease; Mild cognitive impairment; Myelin basic protein; Ubiquitin

Indexed keywords

MYELIN BASIC PROTEIN; UBIQUITIN;

AGE DETERMINATION; AGED; AGING; ALZHEIMER DISEASE; ARTICLE; CADAVER; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FRONTAL CORTEX; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MALE; NEUROPHYSIOLOGY; PRIORITY JOURNAL; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; WHITE MATTER;

EID: 0346995403     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2003.10.002     Document Type: Article

References (38)

1. Ansari K.A., Loch J. Decreased myelin basic protein content of the aged human brain. Neurology. 25:1975;1045-1050.
2. Bennett D.A., Shannon K.M., Beckett L.A., Goetz C.G., Wilson R.S. Metric properties of nurses' ratings of parkinsonian signs with a modified unified Parkinson's disease rating scale. Neurology. 49:1997;1580-1587.
3. Bennett D.A., Wilson R.S., Schneider J.A., Evans D.A., Beckett L.A., Bach J. Natural history of mild cognitive impairment in older persons. Neurology. 59:2002;198-205.
4. Berlet H.H., Volk B. Studies of human myelin proteins during old age. Mech. Ageing Dev. 14:1980;211-222.
5. Brun A., Englund E. A white matter disorder in dementia of the Alzheimer type: a pathoanatomical study. Ann. Neurol. 19:1986;253-262.
6. Ciechanover A., Orian A., Schwartz A.L. The ubiquitin-mediated proteolytic pathway: modes of action and clinical implications. J. Cell Biochem. Suppl. 34:2000;40-51.
7. DeKosky S.T., Ikonomovic M.D., Styren S.D., Beckett L., Wisniewski S., Bennett D.A., Cochran E.J., Kordower J.H., Mufson E.J. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann. Neurol. 51:2002;145-155.
8. Dickson D.W., Wertkin A., Kress Y., Ksiezak-Reding H., Yen S.H. Ubiquitin-immunoreactive structures in normal brains: distribution and development aspects. Lab. Invest. 63:1990;87-99.
9. Folstein M.F., Folstein S.E., McHugh P.R. "Mini-mental state": a practical method for grading the mental state of patients for the clinician. J. Psychiatric Res. 12:1975;189-198.
10. Givogri M., Bongarzone E., Campagnoni A. New insights on the biology of myelin basic protein genes: the neural-immune connection. J. Neurosci. Res. 59:2000;153-159.
11. Goto S., Takahashi R., Kumiyama A., Radák Z., Hayashi T., Takenouchi M., Abe R. Implications of protein degradation in aging. Ann. N.Y. Acad. Sci. 928:2001;54-64.
12. Han, X., M Holtzman, D., McKeel Jr., D.W., Kelley, J., Morris, J.C., 2002. Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis. J. Neurochem. 82:809-18.
13. Kamholz J., Ferra F., Puckett C., Lazzarini R. Identification of three forms of human myelin basic protein by cDNA cloning. Proc. Natl. Acad. Sci. U.S.A. 83:1986;4962-4966.
14. Kordower J.H., Chu Y., Stebbins G.T., DeKosky S.T., Cochran E.J., Bennett D., Mufson E.J. Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment. Ann. Neurol. 49:2001;202-213.
15. Lowe J., Blanchard A., Morrell K., Lennox G., Reynolds L., Billett M., Landon M., Mayer R.J. Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and Mallory bodies in alcoholic liver disease. J. Pathol. 155:1988;9-15.
16. McKhann G., Drachmann D., Folstein M., Katzman R., Price D., Stadlan E. Clinical diagnosis of Alzheimer's disease. Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 34:1984;939-944.
17. Mirra S.S., Heyman A., McKeel D., Sumi S.M., Crain B.J., Brownlee L.M., Vogel F.S., Hughes J.P., van Belle G., Berg L. The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 41:1991;479-486.
18. Mitchell T.W., Nissanov J., Han L.Y., Mufson E.J., Schneider J.A., Cochran E.J., Bennett D.A., Lee V.M., Trojanowski J.Q., Arnold S.E. Novel method to quantify neuropil threads in brains from elders with or without cognitive impairment. J. Histochem. Cytochem. 48:2000;1627-1638.
19. Mitchell T.W., Nissanov J., Han L.Y., Mufson E.J., Schneider J.A., Cochran E.J., Bennett D.A., Lee V.M., Trojanowski J.Q., Arnold S.E. Parahippocampal tau pathology in healthy aging. Ann. Neurol. 51:2002;182-189.
20. Mori H., Kondo J., Ihara Y. Ubiquitin is a component of paired helical filaments in Alzheimer's disease. Science. 235:1987;1641-1644.
21. Mufson E.J., Chen E.Y., Cochran E.J., Beckett L.A., Bennett D.A., Kordower J.H. Entorhinal cortex beta amyloid load in individuals with mild cognitive impairment. Exp. Neurol. 158:1999;469-490.
22. Mufson E.J., Ma S.Y., Cochran E.J., Bennett D.A., Beckett L.A., Jaffar S., Saragovi H.U., Kordower J.H. Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease. J. Comp. Neurol. 427:2000;19-30.
23. Pappolla M.R., Omar R., Saran B. The "normal" brain. "Abnormal" ubiquitinilated deposits highlight an age-related protein change. Am. J. Pathol. 135:1989;585-591.
24. Rees S. A quantitative electron microscopic study of the aging human cerebral cortex. Acta Neuropathol. 36:1976;347-355.
25. Salthouse T.A. Aging and measures of processing speed. Biol. Psychol. 54:2000;35-54.
26. Shaw G., Chau V. Ubiquitin and microtubule-associated protein tau immunoreactivity each define distinct structures with differing distributions and solubility properties in Alzheimer brain. Proc. Natl. Acad. Sci. U.S.A. 85:1988;2854-2858.
27. Sparkes R.S., Mohandas T., Heinzmann C., Roth H.J., Klisak I., Campagnoni A.T. Assignment of the myelin basic protein gene to human chromosome 18q22-qter. Hum. Genet. 75:1987;147-150.
28. Stadtman E. Protein oxidation and aging. Science. 257:1992;1220-1224.
29. Swerdlow P.S., Finley D., Varshavsky A. Enhancement of immunoblot sensitivity by heating of hydrated filters. Anal. Biochem. 156:1986;147-153.
30. Terry R.D., Gonatas N.K., Weiss M. Ultrastructural studies in Alzheimer's presenile dementia. Am. J. Pathol. 44:1964;269-297.
31. van de Lest C.H., Veerkamp J.H., van Kuppevelt T.H. ImageCalc: a microsoft Windows application for quantitative image analysis and comparison. Biotechniques. 18:1995;1050-1055.
32. Wang, D.S., Cochran, E., Bennett, D., Mufson, E., Eckman, C., Dickson, D.W., 2001a. Amyloid, PHF-tau, ubiquitin and synaptic markers in the progression of Alzheimer's disease: immunochemical analyses of frontal cortex from prospectively studied elderly humans. In: Iqbal, K., Sisodia, S.S., Winblad, B. (Eds.), Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics. Wiley, New York, pp. 166-180.
33. Wang D.S., Cochran E., Bennett D.A., Mufson E., Dickson D.W. Changes in myelin basic protein and ubiquitin may contribute to age-related declines in cognition (Abstract). J. Neuropathol. Exp. Neurol. 60:2001;545.
34. Wang G., Khatoon S., Iqbal K., Grundke-Iqbal I. Brain ubiquitin is markedly elevated in Alzheimer disease. Brain Res. 566:1991;146-151.
35. Wilson R.S., Beckett L.A., Barnes L.L., Schneider J.A., Bach J., Evans D.A., Bennett D.A. Individual differences in rates of change in cognitive abilities of older persons. Psychol. Aging. 17:2002a;179-193.
36. Wilson R.S., Mendes De Leon C.F., Barnes L.L., Schneider J.A., Bienias J.L., Evans D.A., Bennett D.A. Participating in cognitively stimulating activities and risk of incident Alzheimer's disease. JAMA. 287:2002;742-748.
37. Wilson R.S., Schneider J.A., Barnes L.L., Beckett L.A., Aggarwal N.T., Cochran E.J., Berry-Kravis E., Bach J., Fox J.H., Evans D.A., Bennett D.A. Effect of apolipoprotein E ε4 allele status on decline in different cognitive systems and development of Alzheimer's disease over a 6-year period. Arch. Neurol. 59:2002;1154-1160.
38. Ylikoski R., Ylikoski A., Erkinjuntti T., Sulkava R., Raininko R., Tilvis R. White matter changes in healthy elderly persons correlate with attention and speed of mental processing. Arch. Neurol. 50:1993;818-824.