Parathyroid hormone (PTH) secretion, PTH mRNA and calcium-sensing receptor mRNA expression in equine parathyroid cells, and effects of interleukin (IL)-1, IL-6, and tumor necrosis factor-α on equine parathyroid cell function

Journal of Molecular Endocrinology

Volumn 31, Issue 3, 2003, Pages 609-620

  Toribio, R E ^a   Kohn, C W ^a   Capen, C C ^a   Rosol, T J ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM SENSING RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PARATHYROID HORMONE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE OVEREXPRESSION; HORSE; IN VITRO STUDY; INHIBITION KINETICS; NONHUMAN; PARATHYROID CELL; PARATHYROID FUNCTION; PARATHYROID HORMONE RELEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE;

ANIMALS; CALCIUM; CELLS, CULTURED; HORSES; INTERLEUKIN-1; INTERLEUKIN-6; PARATHYROID GLANDS; PARATHYROID HORMONE; RECEPTORS, CALCIUM-SENSING; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0346728611     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0310609     Document Type: Article

References (53)

1. Aggarwal BB 2000 Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB. Annals of the Rheumatic Diseases 59 (Suppl 1) i6-16.
2. Aguilera-Tejero E, Sanchez J, Almaden Y, Mayer-Valor R, Rodriguez M & Felsenfeld AJ 1996 Hysteresis of the PTH-calcium curve during hypocalcemia in the dog: effect of the rate and linearity of calcium decrease and sequential episodes of hypocalcemia. Journal of Bone and Mineral Research 11 1226-1233.
3. Aguilera-Tejero E, Estepa JC, Lopez I, Bas S, Garfia B & Rodriguez M 2001 Plasma ionized calcium and parathyroid hormone concentrations in horses after endurance rides. Journal of the American Veterinary Medical Association 219 488-190.
4. Akira S, Taga T & Kishimoto T 1993 Interleukin-6 in biology and medicine. Advances in Immunology 54 1-78.
5. Barron MH, Bruce EH, Moore JN, Norton N, Anders B & Morris DD 1998 Effect of tumor necrosis factor antibody given to horses during early experimentally induced endotoxemia. American Journal of Veterinary Research 59 792-797.
6. Beyer MJ, Freestone JF, Reimer JM, Bernard WV & Rueve ER 1997 Idiopathic hypocalcemia ill foals. Journal of Veterinary Internal Medicine 11 356-360.
7. Breidenbach A, Schlumbohm C & Harmeyer J 1998 Peculiarities of vitamin D and of the calcium and phosphate homeostatic system in horses. Veterinary Research 29 173-186.
8. Brent GA, LeBoff MS, Seely EW, Conlin PR & Brown EM 1988 Relationship beween the concentration and rate of change of calcium and serum intact parathyroid hormone levels in normal humans. Journal of Clinical Endocrinology and Metabolism 67 944-950.
9. Brown AJ, Zhong M, Finch J, Ritter C, McCracken R, Morrissey J & Slatopolsky E 1996 Rat calcium-sensing receptor is regulated by vitamin D but not by calcium. American Journal of Physiology 270 F454-F460.
10. Brown EM 1983 Four-parameter model of the sigmoidal relationship between parathyroid hormone release and extracellular calcium concentration in normal and abnormal parathyroid tissue. Journal of Clinical Endocrinology and Metabolism 56 572-581.
11. Brown EM, Hurwitz S & Aurbach GD 1976 Preparation of viable isolated bovine parathyroid cells. Endocrinology 99 1582-1588.
12. Brown EM, Gamba G, Riccardi D, Lombardi M, Butters R, Kifor O, Sun A, Hediger MA, Lytton J & Hebert SC 1993 Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid. Nature 366 575-580.
13. Bueno AC, Seahorn TL, Cornick-Seahorn J, Horohov DW & Moore RM 1999 Plasma and urine nitric oxide concentrations in horses given below a low dose of endotoxin. American Journal of Veterinary Research 60 969-976.
14. Canaff L & Hendy GN 2002 NF-kappaB mediates transcriptional up-regulation of the human calcium-sensing receptor gene by interleukin-1 beta and tumor necrosis factor-alpha. Journal of Bone and Mineral Research 17 S494.
15. Carlstedt F, Lind L, Rastad J, Stjernstrom H, Wide L & Ljunghall S 1998 Parathyroid hormone and ionized calcium levels are related to the severity of illness and survival in critically ill patients. European Journal of Clinical Investigation 28 898-903.
16. Carlstedt E, Ridefelt P, Lind L & Rastad J 1999 Interleukin-6 induced suppression of bovine parathyroid hormone secretion. Bioscience Reports 19 35-42.
17. Couetil LL, Sojka JF & Nachreiner RF 1998 Primary hypoparathyroidism in a horse. Journal of Veterinary Internal Medicine 12 45-49.
18. Dinarello CA 2000 Proinflammatory cytokines. Chest 118 503-508.
19. Elfers RS, Bayly WM, Brobst DF, Reed SM, Liggitt HD, Hawker CD & Baylink DJ 1986 Alterations in calcium, phosphorus, and C-terminal parathyroid hormone levels in equine acute renal disease. Cornell Veterinarian 76 317-329.
20. Espevik T & Nissen-Meyer J 1986 A highly sensitive cell line, WEHI clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. Journal of Immunological Methods 95 99-105.
21. Farnebo F, Hoog A, Sandelin K, Larsson C & Farnebo LO 1998 Decreased expression of calcium-sensing receptor messenger ribonucleic acids in parathyroid adenomas. Surgery 124 1094-1098.
22. Fasciotto BH, Gorr SU, DeFranco DJ, Levine MA & Cohn DV 1989 Pancreastatin, a presumed product of chromogranin-A (secretory protein-I) processing, inhibits secretion from porcine parathyroid cells in culture. Endocrinology 125 1617-1622.
23. Fasciotto BH, Denny JC, Greeley GH Jr & Cohn DV 2000 Processing of chromogranin A in the parathyroid: generation of parastatin-related peptides. Peptides 21 1389-1401.
24. Felsenfeld AJ & Llach F 1993 Parathyroid gland function in chronic renal failure. Kidney International 43 771-789.
25. Fisher LD & Van Belle G 1993 Biostatistics: a Methodology for the Health Science. New York: John Wiley & Sons Inc.
26. Frank N, Hawkins JF, Couetil LL & Raymond JT 1998 Primary hyperparathyroidism with osteodystrophia fibrosa of the facial bones in a pony. Journal of the American Veterinary Medical Association 212 84-86.
27. Frean SP, Gettinby G, May SA & Lees P 2000 Influence of interleukin-1 beta and hyaluronan on proteoglycan release from equine navicular hyaline cartilage and fibrocartilage. Journal of Veterinay Pharmacology and Therapeutics 23 67-72.
28. Fujii Y, Moreira JE, Orlando C, Maggi M, Aurbach GD, Brandi ML & Sakaguchi K 1991 Endothelin as an autocrine factor in the regulation of parathyroid cells. PNAS 88 4235-4239.
29. Fujimi T, Baba H, Fukase M & Fujita T 1991 Direct inhibitory effect of amino-terminal parathyroid hormone fragment [PTH(1-34)] on PTH secretion front bovine parathyroid primary cultured cells in vitro. Biochemical and Biophysical Research Communication 178 953-958.
30. Harrington DD & Page EH 1983 Acute vitamin D3 toxicosis in horses: case reports and experimental studies of the comparative toxicity vitamins D2 and D3. Journal of the American Veterinary Medical Association 182 1358-1369.
31. Hjalm G, Murray E, Crumley G, Harazim W, Lundgren S, Onyango I, Ek B, Larsson M, Juhlin C, Hellman P, Davis H, Akerstrom G, Rask L & Morse B 1996 Cloning and sequencing of human gp330, a Ca(2+ -binding receptor with potential intracellular signaling properties. European Journal of Biochemistry 239 132-137.
32. Katz CL, Butters RR, Chen CJ & Brown EM 1992 Structure-function relationships for the effects of various aminoglycoside antibiotics on dispersed bovine parathyroid cells. Endocrinology 131 903-910.
33. Kifor O, Moore FD Jr, Wang P, Goldstein M, Vassilev P, Kifor I, Hebert SC & Brown EM 1996 Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism. Journal of Clinical Endocrinology and Metabolism 81 1598-1606.
34. Kilav R, Silver J & Naveh-Many T 1995 Parathyroid hormone gene expression in hypophosphatemic rats. Journal of Clinical Investigation 96 327-333.
35. Liu W, Ridefelt P, Akerstrom G & Hellman P 2001 Differentiation of human parathyroid cells in culture. Journal of Endocrinology 168 417-425.
36. Lundgren S, Hjalm G, Hellman P, Ek B, Juhlin C, Rastad J, Klareskog L, Akerstrom G & Rask L 1994 A protein involved in calcium sensing of the human parathyroid and placental cytotrophoblast cells belongs to the LDL-receptor protein superfamily. Experimental Cell Research 212 344-350.
37. Maenpaa PH, Koskinen T & Koskinen E 1988 Serum profiles of vitamins A, E and D in mares and foals during different seasons. Journal of Animal Science 66 1418-1423.
38. Marr CM, Love S & Pirie HM 1989 Clinical, ultrasonographic and pathological findings in a horse with splenic lymphosarcoma and pseudohyperparathyroidism. Equine Veterinary Journal 21 221-226.
39. Mayer GP & Hurst JG 1978 Sigmoidal relationship between parathyroid hormone secretion rate and plasma calcium concentration in calves. Endocrinology 102 1036-1042.
40. Mithal A, Kifor O, Kifor I, Vassilev P, Butters R, Krapcho K, Simin R, Fuller F, Hebert SG & Brown EM 1995 The reduced responsiveness of cultured bovine parathyroid cells to extracellular Ca2+ is associated with marked reduction in the expression of extracellular Ca(2+)-sensing receptor messenger ribonucleic acid and protein. Endocrinology 136 3087-3092.
41. Moallem E, Kilav R, Silver J & Navch-Many T 1998 RNA-Protein binding and post-transcriptional regulation of parathyroid hormone gene expression by calcium and phosphate. Journal of Biological Chemistry 273 5253-5259.
42. Nielsen PK, Feldt-Rasmussen U & Olgaard K 1996 A direct effect in vitro of phosphate on PTH release from bovine parathyroid tissue slices but not from dispersed parathyroid cells. Nephrology Dialysis Transplantation 11 1762-1768.
43. Nielsen PK, Rasmussen AK, Butters R, Feldt-Rasmussen U, Bendtzen K, Diaz R, Brown EM & Olgaard K 1997 Inhibition of PTH secretion by interleukin-1 beta in bovine parathyroid glands in vitro is associated with an up-regulation of the calcium-sensing receptor mRNA. Biochemical and Biophysical Research Communications 238 880-885.
44. Racke FK & Nemeth EF 1993 Cytosolic calcium homeostasis in bovine parathyroid cells and its modulation by protein kinase C. Journal of Physiology 468 141-162.
45. Richardson DW & Dodge GR 2000 Effects of interleukin-1 beta and tumor necrosis factor-alpha on expression of matrix-related genes by cultured equine articular chondrocytes. American Journal of Veterinary Research 61 624-630.
46. Ronen N, Van Heerden J & van Amstel SR 1992 Clinical and biochemistry findings, and parathyroid hormone concentrations in three horses with secondary hyperparathyroidism. Journal of the South African Veterinary Association 63 134-136.
47. Rosol TJ, Steinmeyer CL, McCauley LK, Grone A, DeWille JW & Capen CC 1995 Sequences of the cDNAs encoding canine parathyroid hormone-related protein and parathyroid hormone. Gene 160 241-243.
48. Sakaguchi K, Santora A, Zimering M, Curcio F, Aurbach GD & Brandi ML 1987 Functional epithelial cell line cloned from rat parathyroid glands. PNAS 84 3269-3273.
49. Schryver HF, Hintz HF & Lowe JE 1974 Calcium and phosphorus in the nutrition of the horse. Cornell Veterinarian 64 493-515.
50. Seethanathan P, Bottoms GD & Schafer K 1990 Characterization of release of tumor necrosis factor, interleukin-1, and superoxide anion from equine white blood cells in response to endotoxin. American Journal of Veterinary Research 51 1221-1225.
51. Slatopolsky E & Delmez JA 1996 Pathogenesis of secondary hyperparathyroidism. Nephrology, Dialysis, Transplantation 11 (Suppl 3) 130-135.
52. Toribio RE, Kohn CW, Chew DJ, Sams RA & Rosol TJ 2001 Comparison of serum parathyroid hormone and ionized calcium and magnesium concentrations and fractional urinary clearance of calcium and phosphorus in healthy horses and horses with enterocolitis. American Journal of Veterinary Research 62 938-947.
53. Toribio RE, Kohn CW, Sams RA, Capen CC & Rosol TJ 2003 Hysteresis and calcium set-point for the calcium parathyroid hormone relationship in healthy horses. General and Comparative Endocrinology 130 279-288.