Interleukin-6 induced suppression of bovine parathyroid hormone secretion

Bioscience Reports

Volumn 19, Issue 1, 1999, Pages 35-42

  Carlstedt, E ^a   Ridefelt, P ^a   Lind, L ^a   Rastad, J ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Hypocalcemia; Il 6; Parathyroid hormone; Proinflammatory cytokines; TNF

Indexed keywords

CALCIUM ION; INTERLEUKIN 6; PARATHYROID HORMONE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CALCIUM BLOOD LEVEL; CALCIUM CELL LEVEL; CONTROLLED STUDY; CRITICAL ILLNESS; CYTOKINE RELEASE; EXTRACELLULAR CALCIUM; HYPOCALCEMIA; NONHUMAN; PARATHYROID HORMONE RELEASE;

ANIMALS; CALCIUM; CATTLE; CELLS, CULTURED; HUMANS; INTERLEUKIN-6; PARATHYROID GLANDS; PARATHYROID HORMONE; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; BOVINAE;

EID: 0032993382     PISSN: 01448463     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020146023812     Document Type: Article

References (27)

1. Burchard, K. W., Gann, D. S., Colliton, J., and Forster, J. (1990) Ionized calcium, parathormone, and mortality in critically ill surgical patients. Ann. Surg. 212:543-9.
2. Zaloga, G. P. (1992) Hypocalcemia in critically ill patients. Crit. Care Med. 20:251-62.
3. McKay, C., Beastall, G. H., Imrie, C. W., and Baxter, J. N. (1994) Circulating intact parathyroid hormone levels in acute pancreatitis. Br. J. Surg 81:357-60.
4. Desai, T. K., Carlson, R. W., and Geheb, M. A. (1988) Prevalence and clinical implications of hypocalcemia in acutely ill patients in a medical intensive care setting. Am. J. Med. 84:209-14.
5. Henderson, S. A., Graham, H. K., and Mollan, R. A. (1992) Serum and other calcium fractions in patients after severe musculoskeletal trauma. Clin.Orthop. 275:306-311.
6. Forman, D. T. and Lorenzo, L. (1991) Ionized calcium: Its significance and clinical usefulness. Ann. Clin. Lab. Sci. 21:297-304.
7. Carlstedt, F., Lind, L., Wide, L., et al. (1997) Serum levels of parathyroid hormone are related to the mortality and severity of illness in patients in the emergency department [see comments]. Eur. J. Clin. Invest 27:977-981.
8. Zaloga, G. P. and Chernow, B. (1987) The multifactorial basis for hypocalcemia during sepsis. Studies of the parathyroid hormone-vitamin D axis. Ann. Intern. Med. 107:36-41.
9. Dettelbach, M. A., Deftos, L. J., and Stewart, A. F. (1990) Intraperitoneal free fatty acids induce severe hypocalcemia in rats: A model for the hypocalcemia of pancreatitis. J. Bone Miner. Res. 5:1249-55.
10. Bone, R. C. (1996) Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: What we do and do not know about cytokine regulation. Crit. Care Med. 24:163-72.
11. Modawer, L. L. (1994) Biology of proinflammatory cytokines and their antagonists. Crit. Care Med. 22:S3-S7.
12. Hotchkiss, R. S. and Karl, I. E. (1996) Calcium: A regulator of the inflammatory response in endotoxemia and sepsis. New Horiz. 4:58-71.
13. Damas, P., Ledoux, D., Nys, M. et al. (1992) Cytokine serum level during severe sepsis in human IL-6 as a marker of severity. Ann. Surg. 215:356-62.
14. Carlstedt, F., Lind, L., and Lindahl, B. (1997) Proinflammatory cytokines, measured in a mixed population on arrival in the emergency department, are relaled to mortality and severity of disease. J. Intern. Med. 242:361-5.
15. 2+ oscillations in parathyroid cells. Biochem. Biophys. Res. Commun 215:903-909.
16. Jüppner, H., Rosenblatt, M., Segre, G., and Hesch, R. (1983) Discrimination between intact and mid-C regional PTH using selective radioimmunoassay systems. Acta Endocrinol 102:543-548.
17. 2+ indicators with greatly improved fluoroseence properties. J. Biol. Chem. 260:3440-3450.
18. Hirano, T. (1998) Interleukin 6 and its receptor: Ten years later. Int. Rev. Immunol. 16:249-284.
19. Ershler, W., Harman, S., and Keller, E. (1997) Immunologic aspects of osteoporosis. Dev. Comp. Immunol. 21:487-499.
20. Gray, A., Mitnick, M., Shapses, S., Ellison, A., Gundberg, C., and Insogna, K. (1996) Circulating levels of interleukin-6 and tumor necrosis factor-alpha are elevated in primary hyperparathyroidism and correlate with markers of bone resorption-a clinical research study. J. Clin. Endocrinol. Metab. 81:3450-3454.
21. Silverberg, S. and Bilezikian, J. (1996) Cytokines in primary hyperparathyroidism-factors that matter. J. Clin. Endocrinol. Metab. 81:3448-3449.
22. af Ekenstam, E., Benson, L., Hallgren, R., Wide, L., and Ljunghall, S. (1990) Impaired secretion of parathyroid hormone in patients with rheumatoid arthritis: Relationship to inflammatory activity. Clin. Endocrinol. Oxf. 32:323-8.
23. Brown, E. M. (1991) Extracellular Ca2+ sensing, regulation of parathyroid cell function, and role of Ca2+ and other ions as extracellular (first) messengers. Phys. Rev. 71:371-411.
24. Vandenabeele, P., Declerq, W., Beyaert, R., and Fiers, W. (1995) Two tumour necrosis factor receptors: Structure and function. Trends Cell Biol. 5:392-399.
25. Masumoto, N., Tasaka, K., Kasahara, K., Miyake, A., and Tanizawa, O. (1991) Purification of gonadotropes and intracellular free calcium oscillation. Effects of gonadotropin-releasing hormone and interleukin-6. J. Biol. Chem. 266:6485-6488.
26. Nielsen, P., Rasmussen, A., Butters, R. et al. (1997) Inhibition of PTH secretion by interleukin-1 beta in bovine parathyroid glands in vitro is associated with an up-regulation of the calcium-sensing receptor mRNA. Biochem. Biophys. Res. Commun. 238:880-885.
27. Weber, M., Michl, P., Auernhammer, C., and Engelhardt, D. (1997) Interleukin-3 and interleukin-6 stimulate cortisol secretion from adult human adrenocortical cells. Endocrinology 138:2207-2210.