The use of c-src knockout mice for the identification of the main toxic signaling pathway of TCDD to induce wasting syndrome

Journal of Biochemical and Molecular Toxicology

Volumn 17, Issue 6, 2003, Pages 305-315

  Vogel, Christoph F A ^a   Zhao, Yeuchao ^a   Wong, Patrick ^a   Young, Naomi F ^a   Matsumura, Fumio ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

c Src; EGFR; mRNA expression; PDGFAA; RT PCR; TCDD; TGF

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CCAAT ENHANCER BINDING PROTEIN BETA; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR A; PROTEIN KINASE P60; RAS PROTEIN; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; INJECTION; KNOCKOUT MOUSE; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION; WASTING SYNDROME;

ACYLTRANSFERASES; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CYTOCHROME P-450 CYP1A1; ENZYME INDUCTION; GENES, SRC; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; SIGNAL TRANSDUCTION; TETRACHLORODIBENZODIOXIN; TRANSFORMING GROWTH FACTOR ALPHA; WASTING SYNDROME;

EID: 0346656772     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbt.10096     Document Type: Article

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