Cardiac L-type calcium channel α1-subunit is increased by cyclic adenosine monophosphate: Messenger RNA and protein expression in intact bone

Journal of Bone and Mineral Research

Volumn 15, Issue 7, 2000, Pages 1275-1285

  Wang, Xi Tao ^a   Nagaba, Shizuka ^a   Nagaba, Yasushi ^a   Leung, Steven W ^a   Wang, Jinsong ^a   Qiu, Weiping ^a   Zhao, Pei Lin ^a   Guggino, Sandra E ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b 929 Ross Building ^*  (United States)

Author keywords

Cartilage; Cyclic adenosine; L type calcium channel; Monosphate; Osteoblast; Osteocalcin

Indexed keywords

CALCITRIOL; CALCIUM CHANNEL; CALCIUM ION; CYCLIC AMP; FURA 2; MESSENGER RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONFOCAL MICROSCOPY; IMMUNOHISTOCHEMISTRY; NONHUMAN; NORTHERN BLOTTING; OSTEOBLAST; OSTEOSARCOMA CELL; PATCH CLAMP; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 0034088273     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2000.15.7.1275     Document Type: Article

References (31)

1. Berridge MJ 1998 Calcium: A life and death signal. Nature 395:645-648.
2. Yamaguchi DT, Hahn TJ, Iida-Klein, Kleeman CR, Muallem S 1987 Parathyroid hormone-activated calcium channels in an osleoblast-like clonal osteosarcoma cell line. cAMP-dependent and cAMP-independent calcium channels. J Biol Chem 262: 7711-7718.
3. 3 metabolites on cytosolic free calcium in confluent mouse osteoblasts. J Biol Chem 262:13168-13173.
4. 3 metabolites dihydropyridine-sensitive calcium currents in clonal rat osteosarcoma cells. J Biol Chem 264:20265-20274.
5. 3 analogs stimulate calcium currents in rat osteosarcoma cells. J Biol Chem 269:23889-23893.
6. 3 and testosterone potentiation of calcium channels in osteosarcoma cells. J Biol Chem 271: 33335-33343.
7. Kumagi H, Sakamoto H, Guggino S, Filburn CR, Sacktor B 1989 Neurotransmitter regulation of cytosolic calcium in osteoblast-like bone cells. Calcif Tissue Int 45:251-254.
8. 3 increases synthesis of the vitamin K-dependent bone protein by osteosarcoma cells. J Biol Chem 255:11660-11663.
9. Noda M, Yoon K, Rodan GA 1988 Cyclic AMP-mediated stabilization of osteocalcin mRNA in rat osteoblast-like cells treated with parathyroid hormone. J Biol Chem 263:18574-18577.
10. Guggino SE, Lajeunesse D, Wagner J, Snyder SH 1989 Bone remodeling signaled by a dihydropyridine and phenylalkylamine-sensitive calcium channel. Proc Natl Acad Sci U S A 86:2957-2960.
11. Perez-Reyes E, Schneider T 1995 Molecular biology of calcium channels. Kidney Int 48:1111-1124.
12. Henry PD 1981 Comparative pharmacology of calcium antagonists: Nifedipine, verapamil and diltiazem. Am J Cardiol 46:1047-1058.
13. Catterall WA 1995 Structure and function of voltage-gated ion channels. Ann Rev Biochem 64:493-531.
14. 1D isoform by parathyroid hormone. Proc Natl Acad Sci USA 92:10914-10918.
15. Loza J, Carpio L, Lawless G, Marzec N, Dziak RD 1995 Role of extracellular calcium influx in EGF-induced osteoblastic cell proliferation. Bone 16:341S-347S.
16. Diebold RJ, Koch WJ, Wllinor PT, Wang JJ, Muthuchamy M, Wieczorek DF, Schwartz A 1992 Mutually exclusive exon splicing of the cardiac calcium channel alpha 1 subunit gene generates developmentally regulated isoforms in the rat heart. Proc Natl Acad Sci USA 89:1497-1501.
17. Malouf NN, McMahon DK, Hainsworth CN, Kay BK 1992 A two-motif form of the major calcium channel subunit in skeletal muscle. Neuron 8:899-906.
18. Celeste AJ, Rosen V, Buecker JL, Kriz R, Wang EA, Wozney JM 1986 Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones. EMBO J 8:1885-1890.
19. Snutch TP, Tomlinsom WJ, Leonard JP, Gilbert MM 1991 Distinct calcium channels are generated by alternate splicing and are differentially expressed in the mammalian CNS. Neuron 7:45-57.
20. Ma Y, Kobrinsky E, Marks AR 1995 Cloning and expression of a novel truncated calcium channel from non-excitable cells. J Biol Chem 270:483-493.
21. Zhang JF, Ellinor PT, Aldrich RW, Tsien RW 1994 Molecular determinants of voltage-dependent inactivation in calcium channels. Nature 372:97-100.
22. 2+ channel splice variants. J Biol Chem 270:10540-10543.
23. Peterson BZ, Johnson BD, Hockerman GH, Acheson M, Scheuer T, Catterall WA 1997 Analysis of the dihydropyridine receptor site of L-type calcium channels by alanine-scanning mutagenesis. J Biol Chem 272:18752-18758.
24. Hockerman GH, Johnson BD, Abbott MR, Scheuer T Catterall WA 1997 Molecular determinants of high affinity phenylalkyIamine block of L-type calcium channels in transmembrane segment IIIS6 and the pore region of the a, subunit. J Biol Chem 272:18759-18765
25. Dirksen RT, Nakai J, Gonzalez A, Imoto K, Beam KG 1997 The S-S6 linker of repeat I is a critical determinant of L-type Ca2+ channel conductance. Biophys J 73:1402-1409.
26. Tang S Mikala G, Bahinski A, Yatani A, Varadi G Schwart A 1993 Molecular localization of ion selectivity sites within the pore of a human L-type cardiac calcium channel. J Biol Chem 268:13026-13029.
27. Garcia J, Nakai J, Imoto K, Beam KG 1997 Role of S4 segments and the leucine haptad motif in the activation of an L-type calcium channel. Biophys J 72:2515-2523.
28. 3. J Biol Chem 271:32981-32985.
29. 2+ and Pi prior to matrix mineralization. J Cell Biochem 57:218-237.
30. Iannotti JP, Naidu S, Noguchi Y, Hunt RM, Brighton CT 1994 Growth plate matrix vesicle biogenesis. The role of intracellular calcium. Clin Orthop 306:222-229.
31. Zimmermann B, Lange K, Mertens P, Bernimoulin JP 1994 Inhibition of chondrogenesis and endochondral mineralization in vitro by different calcium channel blockers. Eur J Cell Biol 63:114-121.