Influence of zearalenone on reproductive system cell proliferation in gilts

Polish Journal of Veterinary Sciences

Volumn 6, Issue 4, 2003, Pages 239-245

  Obremski, K ^a   Gajecki M ^a   Zwierzchowski, W ^a   Zielonka, L ^a   Otrocka Domagala I ^a   Rotkiewicz, T ^a   Mikolajczyk A ^a   Gajecka M ^a   Polak, M ^a  

^a UNIVERSITY OF WARMIA AND MAZURY IN OLSZTYN   (Poland)

Author keywords

Pigs; Proliferation; Reproductive system; Zearalenone

Indexed keywords

ALPHA ZEARALENOL; ZEARALENONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD ANALYSIS; BLOOD LEVEL; CELL PROLIFERATION; CONTROLLED STUDY; ENTEROHEPATIC CIRCULATION; GENITAL SYSTEM; GRANULE CELL; HISTOPATHOLOGY; MONITORING; NONHUMAN; OVARY FOLLICLE; OVARY FOLLICLE ATRESIA; OVIDUCT; SEXUAL MATURATION; UTERUS;

ANIMALS; ANIMALS, NEWBORN; CELL DIVISION; ESTROGENS, NON-STEROIDAL; FEMALE; OVIDUCTS; SWINE; UTERUS; ZEARALENONE; ZERANOL;

ANIMALIA; ZEA;

EID: 0346340790     PISSN: 15051773     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Biehl ML, Prelusky DB, Koritz GD., Hartin KE, Buck WB, Trenholm HL (1993) Biliary excretion and enterohepatic cycling of zearalenone in immature pigs. Toxicol Appl Pharmacol 121:152-159.
2. Blaney BJ, Bloofield RC, Moore C J (1984) Zearalenone intoxication of pig. Aust Vet J 61: 64-68.
3. Basergo R (1991) Growth regulation of the PCNA gene. J Cell Sci 98: 443-436.
4. Bravo R, Frank R, Blundal PA, Mac Donald-Bravo H (1981) Cyclin/PCNA is the auxilliary proteins of DNA polymerase. Nature 326: 515-517.
5. Braw-Tal R (2002) The initiation of follicle growth: the oocyte or the somatic cells? Mol Cell Endocrinol 187: 11-18.
6. Coffey DS (2001) Similarities of prostate and breast cancer: evolution, diet and estrogens. Urology 57 (Suppl 4 A): 31-38.
7. Curtui VG, Gareis M, Usleber E, Martlabauer E (2001) Survey of Romanian slaughtered pigs for the occurrence of mycotoxins ochratoxins A and B, and zearalenone. Food Addit Contam 18: 730-738.
8. Dziuk PJ (1977) Reproduction in pigs. In: Reproduction in domestic animals. Eds: H. H. Cole and P.T. Cupps. Academic Press, New York, pp 455-474.
9. 2) on estrus activity and reproduction in gilts. J Animal Sci 55: 1-10.
10. Farnsworth NR, Bingel AS, Cordel GA, Crane FA, Fong HHS (1975) Potential value of plant as sources of new antifertility agents. J Pharm Sci 64: 535-598
11. Farnsworth ER, Trenholm HL (1981) The effect of acute administration of the mycotoxin zearalenone to female pigs. J Environ Sci Health B 16: 239-252.
12. Gajȩcka M, Jakimiuk E, Polak M, Otwocka-Domagała I, Janowski T, Gajçcki M (2003) The influence of zearalenone application per os on ultrastructure of chosen parts of dog female reproductive system. Proceedings of III International Science Conference - Veterinary Feed Hygiene "Fusarian Mycotoxicoses" - ISBN 83-912200-3-6, Olsztyn 08-09 May 2003, Poland, pp 82-93.
13. Gajçcki M (2002) Zearalenone - undesirable substances in feed. Pol J Vet Sci 5: 117-122.
14. Gajçcki M, Zielonka Ł, Obremski K, Malinowski R, Rotkiewicz T (1998) Niedoceniane - rodzime mikotoksyny w chowie świń. Magazyn Wet (Suppl) 44-47.
15. Gajçcki M, Obremski K, Zielonka Ł, Załuska G (1999) Zagrożenia wystçpowania w paszach zwia̧zków wywołuja̧cych hiperestogenizm u świń. Magazyn Wet (Suppl) 85-87.
16. Gajȩcki M, Obremski K, Zwierzchowski W, Jana B, Zielonka Ł, Gajȩcka M (2001) Mikotoksyny - substancje niepoża̧dane w środkach żywienia zwierza̧t. Życie Wet 77(2): 78-81.
17. Hidy PH, Baldwin RS, Greasham RL, Keithy CL, McMullen JR (1977) Zearalenone and some derivatives. Adv Appl Microbiol 22: 59-82.
18. Hoffmann B, Schuler G (2000) Receptor blockers - general aspects with respect to their use in domestic animal reproduction. Anim Reprod Sci 60-61: 295-312.
19. Inaba T, Namura T, Tani H, Matsuyama S, Torii R, Kawate N, Tamada H, Hatoya S, Kumagai D, Sugiura K, Sawada T (2002) Enhancement of aromatase gene expresion in the mediobasal hypothalamus during anestrus in the beagle bitch. Neurosci Lett 333: 107-110.
20. IARC (1993) IARC (International agency for research on cancer) monographs on the evaluation of the carcinogenic risk of chemicals to humans: some naturally occuring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. Lyon, France, Vol 56, pp 397-444.
21. Katzenellenbogen B (1996) Estrogen Receptors: Bioactivities and Interactions with Cell Signaling Pathways. Biol Rep 54: 287-293.
22. Kim JM, Boone DL, Auyeung A, Tsang BK (1998) Granulosa cell apoptosis induced at the penultimate stage of follicular development is associated with increased levels of Fas and Fas ligand in the rat ovary. Biol Reprod 58: 1170-1176.
23. Kouba M (2003) Quality of organic animal products. Livest Prod Sci 80: 33-40.
24. Krazeisen A, Breitling R, Möller G, Adamski J (2001) Phytoestrogens inhibit human 17β-hydroxysteroid dehydrogenase type 5. Moll Cell Endocrinol 171: 151-162.
25. Krzysiek J, Gregoraszczuk E, Milewicz T, Klimek R (1996) Kontrola wzrostu i atrezji pȩcherzyków jajnikowych. Gin Prakt 4: 39-41.
26. Nakahara K, Saito H, Saito T, Ito M, Ohta N, Takahashi T, Hiroi M (1997) The incidence of apoptotic bodies in membrane granulose can predict prognosis of ova from patients participating in vitro fertilization programs. Fertil Steril 68: 312-317.
27. Mc Nutt SH, Purwin P, Murray C (1928) Vulvovaginitis in swine. J Am Vet Med Assoc 73: 484-492.
28. Mirocha CJ, Christensen CM, (1974) Oestrogenic mycotoxins synthetized by Fusarium. In I.F.H. Purchase (ed) Mycotoxins. Elsevier Scientific Publishing Co, Amsterdam, pp 129-148.
29. Mueller SO (2002) Overviev of in vitro tools to assess the estrogenic and antiestrogenic activity of phytoestrogens. J Chromatogr B 777: 155-165.
30. Obremski K, Zielonka Ł, Załuska G, Zwierzchowski W, Pirus K, Gajçcki M (1999) The influence of low doses of zearalenone on liver enzyme activities in gilts. Proceedings of X Conference "Microscopi fungi - plant pathogens and their metabolites", Poznań, Poland, p 66.
31. Olsen M, Malmlfö H, Pettersson H, Sandholm K, Kiessling KH (1985) Plasma and urinary levels of zearalenone and α-zearalenol in a prepubertal gilt fed zearalenone. Acta Pharmacol Toxicol 56: 239-243.
32. Olsen ME, Malmlof K, Pettersson H, Grajewski J (1991) Influence of dietary fibre on plasma and urinary levels of zearalenone and metabolites in swine. Mycotoxin Res 7: 8-11.
33. Onclin K, Murphy B, Verstegen JP (2002) Comparisons of estradiol, LH and FSH patterns in pregnant and non-pregnant beagle bitches. Theriogenology 57: 1957-1972.
34. Pedersen LJ, Heiskanen T, Damm BI (2003) Sexual motivation in relation to social rank in pair-housed sows. Anim Reprod Sci 75: 39-53.
35. Porter DA, Harman RM, Cowan RG, Quirk SM (2001) Susceptibility of ovarian granulose cells to apoptosis differs in cells isolated before or after the preovulatory LH surge. Moll Cell Endocrinol 176: 13-20.
36. Price KR, Fenwick GR (1985) Naturally occurring oestrogens in foods - a review. Fd Add Contam 2: 73-106.
37. Rhind SM (2002) Endocrine disrupting compounds and farm animals: their properties, actions and routes of exposure. Domestic Animal Endocrinology 23: 179-187.
38. Roulillier P, Matton P, Dufour M, Sirard MA, Guilbault LA (1998) Steroid production, cell proliferation, and apoptosis in cultured bovine antral and mural granulose cells: development of an in vitro model to study estradiol production. Mol Reprod Dev 50: 170-177.
39. Słomczyńska M, Tabarowski Z (2001) Localization of androgen receptor and cytochrome P450 aromatase in the follicle and corpus luteum of the porcine ovary. Anim Reprod Sci 65: 127-134.
40. Sundlof SF, Strickland C (1986) Zearalenone and zeranol: Potential residue problems in livestock. Vet Hum Toxicol 28: 242-250.
41. Sweeney T (2002) Is exposure to endocrine disrupting compounds during fetal/post-natal development affecting the reproductive potential of farm animals? Domestic Animal Endocrinology 23: 203-209.
42. Sydenham EW, Thiel PG, Marasas WFO (1988) Occurrence and chemical determination of zearalenone and alternational monomethyl ether in sorghum - based mixed feeds associated hyperestrogenism in swine. J Agric Food Chem 36: 621-629.
43. Takekida S, Matsuo H, Maruo T (2003) GnRH agonist action on granulose cells at varying follicular stages. Moll Cell Endocrinol 202: 155-164.
44. Ueno Y, Yagasaki S (1975) Toxicological approaches to the metabolites of Fusaria. X. Accelerating effect of zearalenone on RNA and protein syntheses in the uterus of ovariectomized mice. Jpn J Exp Med 45: 199-205.
45. Vanyi A, Bata A, Glavits R, Kovacs F (1994) Perinatal oestrogen syndrome in swine. Acta Vet Hung 42: 433-446.
46. Zwierzchowski W (2002) Influence of a low dose of zearalenone on reproductive system in sexually immature gilts. Doctoral dissertation (in Polish). University of Warmia and Mazury in Olsztyn, Poland.