The incidence of apoptotic bodies in membrana granulosa can predict prognosis of ova from patients participating in in vitro fertilization programs

Fertility and Sterility

Volumn 68, Issue 2, 1997, Pages 312-317

  Nakahara, Kenji ^a   Ohta, Nobuhiko ^a   Saito, Hidekazu ^a   Takahashi, Toshifumi ^a   Saito, Takakazu ^a   Hiroi, Masahiko ^a   Ito, Mariko ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Apoptotic bodies; Cumulus cells; Granulosa cells; Human; In vitro fertilization; Intrafollicular steroid concentration

Indexed keywords

CHORIONIC GONADOTROPIN;

ADULT; APOPTOSIS; ARTICLE; CUMULUS OOPHORUS; EMBRYO; FEMALE; FERTILIZATION IN VITRO; FLUORESCENCE MICROSCOPY; GRANULOSA CELL; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; OVARY; OVARY FOLLICLE; OVARY HYPERSTIMULATION; OVULATION INDUCTION; PRIORITY JOURNAL; PROGNOSIS; RADIOIMMUNOASSAY;

EID: 0343924430     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(97)81521-X     Document Type: Article

References (20)

1. Tilly JL, Kowalski KIN, Johnson AL, Hsueh AD. Involvement of apoptosis in ovarian follicle atresia and postovulatory regression. Endocrinology 1991;129:2799-801.
2. Palumbo A, Yeh J. In situ localization of apoptosis in the rat ovary during follicle atresia. Biol Reprod 1994;51:888-95.
3. Grochowski D, Wolczynski S, Kuczynski W, Kulikowski M, Szamatowicz M. The results of an in vitro fertilization program: two regimens of superovulation. Gynecol Endocrinol 1995;9:59-62.
4. Billig H, Furuta I, Hsueh AJ. Gonadotropin-releasing hormone directly induces apoptotic cell death in the rat ovary: biochemical and in situ detection of deoxyribonucleic acid fragmentation in granulosa cells. Endocrinology 1994; 134:245-52.
5. Leoncini L, Del Vecchio MT, Megha T, Barbini P, Galieni P, Pileri S, et al. Correlation between apoptotic and proliferative indices in malignant non-Hodgkin's lymphoma. Am J Pathol 1993;142:755-63.
6. Wheeler TM, Rogers E, Aihara M, Scardino PT, Thompson TC. Apoptotic index as a biomarker in prostatic intraepithelial neoplasma (PIN) and prostatic cancer. J Cell Biol 1994; 19:202-7.
7. Nakahara K, Saito H, Saito T, Ohta N, Ito M, Tezuka N, et al. Incidence of apoptotic bodies in membrana granulosa of the patients participating in an in vitro fertilization. Fertil Steril 1997;67:302-8.
8. Tilly JL. Apoptosis and the ovary: a fashionable trend or food for thought? Fertil Steril 1997;67:226-8.
9. Tavmergen E, Tavmergen EN, Capanoglu R. Do analogues of gonadotropin releasing hormone influence follicular fluid steroid levels, oocyte maturity and fertilization rate? Hum Reprod 1992; 7:479-82.
10. Kamel MA, Zabel G, Bernart W, Neulen J, Breckwoldt M. Comparison between prolactin, gonadotrophins and steroid hormones in serum and follicular fluid after stimulation with gonadotrophin-releasing hormone agonists and human menopausal gonadotrophin for an in-vitro fertilization programme. Hum Reprod 1994;9:1803-6.
11. Quinn P, Warnes GM, Kerin JF, Kirby C. Culture factors affecting the success rate of in vitro fertilization and embryo transfer. Ann NY Acad Sci 1985;442:195-204.
12. Saito H, Hiroi H. Correlation between the follicular gonadotropin inhibitor and the maturity of the ovum-corona-cumulus complex. Fertil Steril 1986;46:66-72.
13. Saito H, Hirayama T, Koike K, Saito T, Nohara M, Hiroi M. Cumulus mass maintains embryo quality. Fertil Steril 1994;62:555-8.
14. Piquette GN, Tilly JL, Prichard L, Simon C, Polan ML. Detec-tion of apoptosis in human and rat ovarian follicles. J Soc Gynecol Invest 1994;1:297-301.
15. Chun SY, Billig H, Tilly JL, Furuta I, Tsafriri A, Hsueh AJ. Gonadotropin suppression of apoptosis in cultured preovulatory follicles: mediatory role of endogenous insulin-like growth factor I. Endocrinology 1994;135:1845-53.
16. Tilly JL, Kowalski KI, Schomberg DW, Hsueh AJ. Apoptosis in atretic ovarian follicles is associated with selective decreases in messenger ribonucleic acid transcripts for gonadotropin receptors and cytochrome P450 aromatase. Endocrinology 1992;131:1670-6.
17. Dirnfelt M, Goldman S, Gonen Y, Koifman M, Lissak A, Kraiem Z, et al. Functional differentiation in progesterone secretion by granulosa versus cumulus cells in the human preovulatory follicle and the effect of different induction of ovulation protocols. Fertil Steril 1993;60:1025-30.
18. Amsterdam A, Koch Y, Leiberman ME, Lindner HR. Distribution of binding sites for human chorionic gonadotropin in the preovulatory follicle of the rat. J Cell Biol 1975;67:894-900.
19. Lawrence TS, Deckel N, Beers WH. Binding of human chorionic gonadotropin by rat cumuli oophori and granulosa cells: a comparative study. Endocrinology 1980;106:1114-8.
20. Hirshfield AN. Rescue of atretic follicles in vitro and in vivo. Biol Reprod 1989;40:181-90.