A microdialysis model to examine nasal drug delivery and olfactory absorption in rats using lidocaine hydrochloride as a model drug

International Journal of Pharmaceutics

Volumn 269, Issue 2, 2004, Pages 311-322

  Bagger, Morten ^a   Bechgaard, Erik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Blood brain barrier integrity; Lidocaine; Microdialysis; Nasal drug delivery; Olfactory pathway; Pharmacokinetics; Rats

Indexed keywords

LIDOCAINE; PRILOCAINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; BLOOD; BLOOD BRAIN BARRIER; BRAIN REGION; CALCULATION; CALIBRATOR; CONTROLLED STUDY; CORPUS STRIATUM; DRAIN; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DELIVERY SYSTEM; DRUG STABILITY; DRUG TRANSPORT; IMPLANTATION; IN VIVO STUDY; MALE; MEASUREMENT; MECHANICAL PROBE; MICRODIALYSIS; NONHUMAN; NOSE CAVITY; OLFACTORY SYSTEM; PRIORITY JOURNAL; PROCESS MODEL; RAT; RAT STRAIN; SYSTEMIC CIRCULATION; TIME;

EID: 0346099212     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2003.09.017     Document Type: Article

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