Sonic Hedgehog (SHH) expression in developing and regenerating axolotl limbs

Journal of Experimental Zoology

Volumn 284, Issue 2, 1999, Pages 197-206

  Torok, Maureen A ^a,c   Gardiner, David M ^a   Izpisúa Belmonte, Juan Carlos ^b   Bryant, Susan V ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARABYSTOMA MEXICANUM; DEVELOPMENTAL GENETICS; GENE EXPRESSION; REGENERATION; RETINOIC ACID; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE GRAFT;

AMBYSTOMA; AMINO ACID SEQUENCE; AMPUTATION; ANIMALS; DNA PRIMERS; EMBRYONIC INDUCTION; EXTREMITIES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; MOLECULAR SEQUENCE DATA; PROTEINS; REGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY; TRANS-ACTIVATORS; TRETINOIN;

EID: 0033169081     PISSN: 0022104X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-010X(19990701)284:2<197::AID-JEZ9>3.0.CO;2-F     Document Type: Article

References (46)

1. Akimenko MA, Ekker M. 1995. Anterior duplication of the Sonic hedgehog expression pattern in the pectoral fin buds of zebrafish treated with retinoic acid. Dev Biol 170:243-247.
2. Anderson R, Reginelli AD, Li S, Van Way SM, Muneoka M. ZPA signaling and the regulation of Sonic hedgehog expression in the mouse and chick limb buds. Dev Biol, submitted.
3. Bordzilovskaya NP, Dettlaff TA, Duhon S, Malacinski GM. 1989. Developmental-stage series of axolotl embryos. In: Armstrong JB, Malacinsky GM, editors. Developmental biology of the axolotl. New York: Oxford University Press.
4. Bryant SV, Gardiner DM. 1992. Retinoic acid, local cell-cell interactions, and pattern formation in vertebrate limbs. Dev Biol 152:1-25.
5. Bryant SV, Iten L. 1974. The regulative ability of the limb regeneration blastema of Notophthalmus viridescens: experiments in situ. Wilhelm Roux' Archiv 174:90-101.
6. Bryant SV, Muneoka K. 1986. Views of limb development and regeneration. Trends Genet 2:153-159.
7. Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA. 1996. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383:407-413.
8. Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP. 1993. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75:1417-1430.
9. Eichele G, Tickle C, Alberts BM. 1985. Studies on the mechanism of retinoid-induced pattern duplications in the early chick limb bud: temporal and spatial aspects. J Cell Biol 101:1913-1920.
10. Ekker SC, Ungar AR, Greenstein P, von Kessler DP, Porter JA, Moon RT, Beachy PA. 1995. Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. Curr Biol 5:944-955.
11. Endo T, Yokoyama H, Tamura K, Ide H. 1997. Shh expression in developing and regenerating limb buds of Xenopus laevis. Dev Dyn 209:227-232.
12. Gardiner DM, Blumberg B, Komine Y, Bryant SV. 1995. Regulation of HoxA expression in developing and regenerating axolotl limbs. Development 121:1731-1741.
13. Harrison RG. 1925. The effect of reversing the mediolateral or transverse axis of the fore-limb bud in the salamander embryo (Amblystoma punctatum). Roux's Arch 106:469-502.
14. Harrison RG. 1969. Organization and development of the embryo. New Haven, CT: Yale University Press.
15. Hayamizu TF, Bryant SV. 1994. Reciprocal changes in Hox D13 and RAR-β2 expression in response to retinoic acid in chick limb buds. Dev Biol 166:123-132.
16. Honig LS, Summerbell D. 1985. Maps of strength of positional signalling activity in the developing chick wing bud. J Embryol Exp Morphol 87:163-174.
17. Imokawa Y, Yoshizato K. 1997. Expression of Sonic hedgehog gene in regenerating newt limb blastema recapitulates that in developing limb buds. Proc Natl Acad Sci USA 94:9159-9164.
18. Iten LE, Bryant SV. 1975. Interactions between blastema and stump in the establishment of the anterior-posterior and proximal-distal organization of the limb regenerate. Dev Biol 44:119-147.
19. Javois LC, Iten LE. 1986. The handedness and origin of supernumerary limb structures following 180° rotation of the chick wing bud on its stump. J Embryol Exp Morphol 91:135-152.
20. Krauss S, Concordet JP, Ingram PW. 1993. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75:1431-1444.
21. Laufer E, Nelson CE, Johnson RL, Morgan BA, Tabin C. 1994. Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79:993-1003.
22. López-Martínez A, Chang DT, Chiang C, Porter JA, Ros MA, Simandl BK, Beachy PA, Fallon JF. 1995. Limb patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage. Curr Biol 5:791-796.
23. Lu H-C, Revelli J-P, Goering L, Thaller C, Eichele G. 1997. Retinoid signalling is required for the establishment of a ZPA and for the expression of Hoxb-8, a mediator of ZPA formation. Development 124:1643-1651.
24. Mullen L, Torok MA, Bryant SV, Gardiner DM. 1996. Nerve dependency of regeneration: role of Dlx and FGF signaling in amphibian limb regeneration. Development 122:3487-3497.
25. Niswander L, Jeffrey S, Martin GR, Tickle C. 1994. A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371:609-612.
26. Noji S, Nohno T, Koyama E, Muto K, Ohyama K, Aoki Y, Tamura K, Ohsugi K, Ide H, Taniguchi S, Saito T. 1991. Retinoic acid induces polarizing activity but is unlikely to be a morphogen in the chick limb bud. Nature 350:83-86.
27. Noramly S, Pisenti J, Abbott U, Morgan B. 1996. Gene expression in the limbless mutant: polarized gene expression in the absence of Shh and the AER. Dev Biol 179:339-346.
28. Ohsugi K, Gardiner DM, Bryant SV. 1997. Cell cycle length affects gene expression and pattern formation in limbs. Dev Biol 189:13-21.
29. Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ, Moses K, Beachy PA. 1995. The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature 374:363-366.
30. Riddle RD, Johnson RL, Laufer E, Tabin C. 1993. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75:1401-1416.
31. Rodriguez C, Kos R, Macias D, Abbott UK, Izpisua-Belmonte JC. 1996. Shh, HoxD, Bmp-2, and Fgf-4 gene expression during development of the polydactylous talpid2, diplopodia1, and diplopodia4 mutant chick limb buds. Dev Genet 19:26-32.
32. Roelink H, Augsburger A, Heemskerk J, Korzh V, Norlin S, Ruiz i Altaba A, Tanabe Y, Placzek M, Edlund T, Jessell TM, Dodd J. 1994. Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76:761-775.
33. Ros MA, Lopez-Martinez A, Simandl BK, Rodriguez C, Izpisua-Belmonte JC, Dahn R, Fallon JF. 1996. The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions. Development 122:2319-2330.
34. Saunders JW Jr, Gasseling MT. 1968. Ectodermal-mesenchymal interactions in the origin of limb symmetry. In: Fleishmajer R, Billingham RE, editors. Epithelial-mesenchymal interactions. Baltimore: Williams & Wilkins. p 78-97.
35. Saunders JW Jr, Gasseling MT, Gfeller S. 1958. Interactions of ectoderm and mesoderm in the origin of axial relationships in the wing of the fowl. J Exp Zool 137:39-74.
36. Sessions SK, Wanek N, Bryant SV. 1989. Effects of localized application of retinoic acid on pattern in developing and regenerating salamander limbs. Am Zool 29:73A.
37. Shubin NH, Alberch P. 1986. A morphogenetic approach to the origin and basic organization of the tetrapod limb. Evol Biol 20:319-387.
38. Tamura K, Yokouchi Y, Kuroiwa A, Ide H. 1997. Retinoic acid changes the proximodistal developmental competence and affinity of distal cells in the developing chick limb bud. Dev Biol 188:224-234.
39. Tank PW, Carlson BM, Connelly TG. 1977. A scanning electron microscopic comparison of the development of embryonic and regenerating limbs in the axolotl. J Exp Zool 201:417-429.
40. Tickle C, Alberts B, Wolpert L, Lee J 1982. Local application of retinoic acid to the limb bond [sic] mimics the action of the polarizing region. Nature 296:564-566.
41. Tickle C, Lee J, Eichele G. 1985. A quantitative analysis of the effect of all-trans-retinoic acid on the pattern of chick wing development. Dev Biol 109:82-95.
42. Tickle C, Summerbell D, Wolpert L. 1975. Positional signalling and specification of digits in chick limb morphogenesis. Nature 254:199-202.
43. Torok M, Gardiner DM, Shubin N, Bryant SV. 1998. Expression of HoxD genes in developing and regenerating axolotl limbs. Dev Biol 1200:225-233.
44. Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ. 1996. Regulation of rate of cartilage differentiation by Indian Hedgehog and PTH-related protein. Science 273:613-622.
45. Wanek N, Gardiner DM, Muneoka K, Bryant SV. 1991. Conversion by retinoic acid of anterior cells into ZPA cells in the chick wing bud. Nature 350:81-83.
46. Yang Y, Drossopoulou G, Chuang PT, Duprez D, Marti E, Bumcrot D, Vargesson N, Clarke J, Niswander L, McMahon A, Tickle C. 1997. Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb. Development 124:4393-4404.