End-of-life care in geriatric psychiatry

Clinics in Geriatric Medicine

Volumn 19, Issue 4, 2003, Pages 841-856

  Goy, Elizabeth ^a   Ganzini, Linda ^a  

^a PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE;

ANXIETY DISORDER; CLINICAL TRIAL; DELIRIUM; DEMENTIA; DEPRESSION; GERONTOPSYCHIATRY; HUMAN; INCIDENCE; PALLIATIVE THERAPY; PREVALENCE; REVIEW;

EID: 0345707534     PISSN: 07490690     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0749-0690(03)00029-6     Document Type: Review

References (113)

1. World Health Organization. Cancer pain relief and palliative care. Technical Report Series 804. Geneva;1990.
2. Medicare Rights Center. A technical guide to the Medicare home health benefits: care for people with advanced illnesses. New York, NY: Medicare Rights Center; 1998.
3. National Hospice and Palliative Care Organization. Facts and figures on hospice care in America. Alexandria, VA: National Hospice and Palliative Care Organization; 2003.
4. Ganzini L, Nelson HD, Schmidt TA, Kraemer DF, Delorit MA, Lee MA. Physicians' experiences with the Oregon Death with Dignity Act. N Engl J Med 2000;342:557-63.
5. Ganzini L, Harvath TA, Jackson A, Goy ER, Miller LL, Delorit MA. Experiences of Oregon nurses and social workers with hospice patients who requested assistance with suicide. N Engl J Med 2002;347:582-8.
6. Chochinov HM, Hack T, Hassard T, Kristjanson LJ, McClement S, Harlos M. Dignity in the terminally ill: a cross-sectional, cohort study. Lancet 2002;360:2026-30.
7. Chochinov HM. Psychiatry and terminal illness. Can J Psychiatry 2000;45:143-50.
8. Werth JL, Gordon JR, Johnson Jr RR. Psychosocial issues near the end of life. Aging Ment Health 2002;6:402-12.
9. Clarke DM, Mackinnon AJ, Smith GC, McKenzie DP, Herrman HE. Dimensions of psychopathology in the medically ill. Psychosomatics 2000;41:418-25.
10. Betts Adams K. Depressive symptoms, depletion, or developmental change? Withdrawal, apathy, and lack of vigor in the Geriatric Depression Scale. Gerontologist 2001;41:768-77.
11. Lander M, Wilson K, Chochinov HM. Death and dying. Depression and the dying older patient. Clin Geriatr Med 2000;16:335-56.
12. Chochinov HM, Wilson KG, Enns M, Lander S. Prevalence of depression in the terminally ill: effects of diagnostic criteria and symptom threshold judgments. Am J Psychiatry 1994;151:537-40.
13. Lloyd-Williams M. Difficulties in diagnosing and treating depression in the terminally ill cancer patient. Postgrad Med J 2000;76:555-8.
14. NIH Consensus Development Panel on Depression in Late Life. Diagnosis and treatment of depression in late life. JAMA 1992;268:1018-24.
15. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, IV. Washington, DC: American Psychiatric Press; 1994.
16. Block SD. Assessing and managing depression in the terminally ill patient. Ann Intern Med 2000;132:209-18.
17. Lees N, Lloyd-Williams M. Assessing depression in palliative care patients using the visual analog scale: a pilot study. Eur J Cancer Care 1999;8:220-3.
18. Chochinov HM, Wilson KG, Enns M, Lander S. "Are you depressed? " Screening for depression in the terminally ill. Am J Psychiatry 1997;154:674-6.
19. Lloyd-Williams M. Screening for depression in palliative care patients: a review. Eur J Cancer Care 2001;10:31-5.
20. Kroenke K, Spitzer RL, Williams JBW. The PHQ-9. Validity of a brief depression severity measure. J Gen Intern Med 2001;16:606-13.
21. Zigmund AS, Snaith RP. The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand 1983;67:361-70.
22. Urch C, Chamberlain J, Field G. The drawback of the Hospital Anxiety and Depression Scale in the assessment of depression in hospice inpatients. Palliat Med 1998;12:395-6.
23. Beck AT. Beck depression inventory. San Antonio, TX: The Psychological Corporation; 1987.
24. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982;17:37-49.
25. Goodwin PJ, Leszcz M, Ennis M, Koopmans J, Vincent L, Guther H, et al. The effect of group psychosocial support on survival in metastatic breast cancer. N Engl J Med 2001;345:1719-26.
26. Turk DC, Feldman CS. A cognitive-behavioral approach to symptom management in palliative care. In: Chochinov HM, Breitbart W, editors. Handbook of psychiatry in palliative medicine. New York: Oxford University Press; 2000. p. 223-39.
27. Rodin G, Gillies LA. Individual psychotherapy for the patient with advanced disease. In: Chochinov HM, Breitbart W, editors. Handbook of psychiatry in palliative medicine. New York: Oxford University Press; 2000. p. 189-96.
28. Olin J, Masand P. Psychostimulants for depression in hospitalized cancer patients. Psychosomatics 1996;37:57-62.
29. Breitbart W, Strout D. Delirium in the terminally ill. Clin Geriatr Med 2000;16:357-72.
30. Payne DK, Massie MJ, Anxiety in palliative care. In: Chochinov HM, Breitbart W, editors. Handbook of psychiatry in palliative medicine. New York: Oxford University Press; 2000. p. 63-74.
31. Barraclough J. ABC of palliative care: depression, anxiety, and confusion. BMJ 1997;315:1365-8.
32. Mosenthal AC, Lee KF. Management of dyspnea at the end of life: relief for patients and surgeons. J Am Coll Surg 2002;194:377-86.
33. Jacobsen P, Bovberg D, Redd W. Anticipatory anxiety in women receiving chemotherapy for breast cancer. Health Psychol 1993;12:469-75.
34. Derogatis LR, Melisaratos N. The brief symptom inventory: an introductory report. Psychol Med 1983;13:595-605.
35. Inouye SK, Bogardus Jr ST, Charpentier PA, Leo-Summers L, Acapora D, Holford TR, et al. A multicomponent intervention to prevent delirium in hospitalized older patients. N Engl J Med 1999;340:669-76.
36. Lipowski ZJ. Delirium: acute confusional states. New York: Oxford University Press; 1990.
37. Practice Management Information Corporation. International classification of diseases, 9th revision, clinical modification. 5th edition. Los Angeles, CA; 1997.
38. Breitbart W, Chochinov HM, Passik S. Psychiatric aspects of palliative care. In: Doyle D, Hanks GWC, MacDonald N, editors. Oxford textbook of palliative medicine. 2nd edition. New York: Oxford University Press; 1998. p. 933-54.
39. American Psychiatric Association. Practice guideline for the treatment of patients with delirium. Am J Psychiatry Suppl 1999;156:1-20.
40. Farrell K, Ganzini L. Misdiagnosing delirium as depression in medically-ill elderly patients. Arch Intern Med 1995;155:2459-64.
41. Liptzin B, Levkoff SE. An empirical study of delirium subtypes. Br J Psychiatry 1992;161:843-5.
42. O'Keeffe ST, Lavan JN. Clinical significance of delirium subtypes in older people. Age Ageing 1999;28:115-9.
43. Meagher DJ, O'Hanlon D, O'Mahony E, Casey PR, Trzepacz PT. Relationship between symptoms and motoric subtype of delirium. J Neuropsychiatry Clin Neurosci 2000;12:51-6.
44. Casarett DJ, Inouye SK. Diagnosis and management of delirium near the end of life. Ann Intern Med 2001;135:32-40.
45. Folstein MF, Folstein SE, McHugh PR. Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-98.
46. Trzepacz PT, Baker RW, Greenhouse J. A symptom rating scale for delirium. Psychiatry Res 1988;23:89-97.
47. Breitbart W, Rosenfeld B, Roth A, Smith MJ, Cohen K, Passik S. The Memorial Delirium Assessment Scale. J Pain Symptom Manage 1997;13:128-37.
48. Inouye SK, van Dyck CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI. Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med 1990;113:941-8.
49. Smith MJ, Breitbart WS, Platt MM. A critique of instruments and methods to detect, diagnose, and rate delirium. J Pain Symptom Manage 1995;10:35-77.
50. Fann JR. The epidemiology of delirium: a review of studies and methodological issues. Semin Clin Neuropsychiatry 2000;5:64-74.
51. Gagnon P, Allard P, Masse B, DeSerres M. Delirium in terminal cancer: a prospective study using daily screening, early diagnosis and continuous monitoring. J Pain Symptom Manage 2000;19:412-26.
52. Bruera E, Miller L, McCallion J, Macmillan K, Krefting L, Hanson J. Cognitive failure in patients with terminal cancer: a prospective study. J Pain Symptom Manage 1992;7:192-5.
53. Lawlor PG, Gagnon B, Mancini IL, Pereira JL, Hanson J, Suarez-Almazor ME, et al. Occurrence, causes, and outcome of delirium in patients with advanced cancer: a prospective study. Arch Intern Med 2000;160:786-94.
54. Massie MJ, Holland J, Glass E. Delirium in terminally ill cancer patients. Am J Psychiatry 1983;140:1048-50.
55. Pereira J, Hanson J, Bruera E. The frequency and clinical course of cognitive impairment in patients with terminal cancer. Cancer 1997;79:835-42.
56. Minagawa H, Uchitomi Y, Yamawaki S, Ishitani K. Psychiatric morbidity in terminally ill cancer patients. A prospective study. Cancer 1996;78:1113-7.
57. Trzepacz PT. Delirium: advances in diagnosis, pathophysiology, and treatment. Psychiatr Clin N Am 1996;19:429-48.
58. Tune LE. Serum anticholinergic activity levels and delirium in the elderly. Semin Clin Neuropsychiatry 2000;5:149-53.
59. Francis J, Martin D, Kapoor WN. A prospective study of delirium in hospitalized elderly. JAMA 1990;263:1097-101.
60. Marcantonio ER, Juarez G, Goldman L, Mangione CM, Ludwig LE, Lind L, et al. The relationship of postoperative delirium with psychoactive medications. JAMA 1994;272:1518-22.
61. Fainsinger RL, Tapper M, Bruera E. A perspective on the management of delirium in terminally ill patients on a palliative care unit. J Palliat Care 1993;9:4-8.
62. Lynch EP, Lazor MA, Gellis JE, Orav J, Goldman L, Marcantonio ER. The impact of postoperative pain on the development of postoperative delirium. Anesth Analg 1998;86:781-5.
63. Brucra E, Fainsinger RL, Miller MJ, Kuehn N. The assessment of pain intensity in patients with cognitive failure: a preliminary report. J Pain Symptom Manage 1992;7:267-70.
64. Caraceni A, Nanni O, Maltoni M, Piva L, Indelli M, Arnoldi E, et al. Impact of delirium on the short term prognosis of advanced cancer patients. Cancer 2000;89:1145-9.
65. Morita T, Tsunoda J, Inoue S, Chihara S. The Palliative Prognostic Index: a scoring system for survival prediction of terminally ill cancer patients. Support Care Cancer 1999;7:128-33.
66. Metitieri T, Bianchetti A, Trabucchi M. Delirium as a predictor of survival in older patients with advanced cancer. Arch Intern Med 2000;160:2866-8.
67. Fainsinger RL, De Moissac D, Mancini I, Oneschuk D. Sedation for delirium and other symptoms in terminally ill patients in Edmonton. J Palliat Care 2000;16:5-10.
68. Fainsinger RL, Waller A, Bercovici M, Bengtson K, Landman W, Hosking M, et al. A multi-centre international study of sedation for uncontrolled symptoms in terminally ill patients. Palliat Med 2000;14:257-65.
69. Beauchamp TL, Childress JF. Principles of biomedical ethics. 4th edition. New York: Oxford University Press, Inc.; 1994.
70. Morrison RS, Siu AL. Survival in end-stage dementia following acute illness. JAMA 2000;284:47-52.
71. Volicer L. Alzheimer's disease and dementia: management of severe Alzheimer's disease and end-of-life issues. Clin Geriatr Med 2001;17:377-91.
72. Volicer L, Hurley A. Hospice care for patients with advanced progressive dementia. New York, NY: Springer Publishing Company, Inc.; 1998.
73. Luchins DJ, Hanrahan P, Murphy K. Criteria for enrolling dementia patients in hospice. J Am Geriatr Soc 1997;45:1054-9.
74. Reisberg B. Functional Assessment Staging (FAST). Psychopharmacol Bull 1988;24:653-9.
75. Stuart B, Herbst L, Kinbrunner B, et al. Medical Guidelines for Determining Prognosis in Selected Non-Cancer Diseases. Arlington, VA: National Hospice Organization; 1995.
76. Chen WT, Wang SJ, Lu SR, Fuh JL. Which level of care is preferred for end-stage dementia? Survey of Taiwanese caregivers. J Geriatr Psychiatry Neurol 2002;15:16-9.
77. Potkins D, Bradley S, Shrimanker J, O'Brien J, Swann A, Ballard C. End of life treatment decisions in people with dementia: caregivers' views and the factors which influence them. Int J Geriatr Psychiatry 2000;15:1005-8.
78. Luchins DJ, Hanrahan P. What is the appropriate level of health care for end-stage dementia patients? J Am Geriatr Soc 1993;41:25-30.
79. Hurley AC, Volicer L. Alzheimer disease: "It's okay, Mama, if you want to go, it's okay." JAMA 2002;288:2324-31.
80. Meier DE, Ahronheim JC, Morris J, Baskin-Lyons S, Morrison RS. High short-term mortality in hospitalized patients with advanced dementia: lack of benefit of tube feeding. Arch Intern Med 2001;161:594-9.
81. Mitchell SL, Kiely DK, Lipsitz LA. The risk factors and impact on survival of feeding tube placement in nursing home residents with severe cognitive impairment. Arch Intem Med 1997;157:327-32.
82. Peck A, Cohen CE, Mulvilhill MN. Long-term enteral feeding of aged demented nursing home patients. J Am Geriatr Soc 1990;38:1195-8.
83. Gillick MR. Rethinking the role of tube feeding in patients with advanced dementia. N Engl J Med 2000;342:206-10.
84. Frissoni GB, Franzoni S, Bellelli G, Morris J, Warden V. Overcoming eating difficulties in the severely demented. In: Volicer L, Hurley A, editors. Hospice care for patients with advanced progressive dementia. New York, NY: Springer Publishing Company, Inc.; 1998. p. 48-67.
85. Fabiszewski KJ, Volicer B, Volicer L. Effect of antibiotic treatment on outcome of fevers in institutionalized Alzheimer patients. JAMA 1990;263:3168-72.
86. Hanrahan P, Raymond M, McGowan E, Luchins DJ. Criteria for enrolling dementia patients in hospice: a replication. Am J Hosp Palliat Care 1999;16:395-400.
87. Van der Steen JT, Ooms ME, van der Wal G, Ribbe MW. Pneumonia: the demented patient's best friend? Discomfort after starting or withholding antibiotic treatment. J Am Geriatr Soc 2002;50:1681-8.
88. Shuster Jr JL. Palliative care for advanced dementia. Clin Geriatr Med 2000;16:373-86.
89. Jeste DV, Wragg RE, Salmon DP, Harris MJ, Thal LJ. Cognitive deficits of patients with Alzheimer's disease with and without delusions. Am J Psychiatry 1992;149:184-9,
90. Lyketsos CG, Steinberg M, Tschanz JT, Norton MC, Steffens DC, Breitner JCS. Mental and behavioral disturbances in dementia: findings from the Cache County study on memory and aging. Am J Psychiatry 2000;157:708-14.
91. Bums A, Jacoby R, Levy R. Psychiatric phenomena in Alzheimer's disease, I: disorders of thought content. Br J Psychiatry 1990;157:72-6.
92. Ballard CG, O'Brien J, James I, Swann A. Identification and measurement of behavioural and psychological symptoms in dementia. In: Ballard CG, O'Brien J, James I, Swann A, editors. Dementia: management of behavioral and psychological symptoms. New York: Oxford University Press; 2001. p. 3-15.
93. Geda YE, Rummans TA. Pain: cause of agitation in elderly individuals with dementia. Am J Psychiatry 1999;156:1662-3.
94. Alexopoulos GS, Silver JM, Kahn DA, Frances A, Carpenter D. Treatment of agitation in older persons with dementia. Postgraduate Medicine Special Report March 1998;286:1-80.
95. Sloane PD, Rader J, Barrick AL, et al. Bathing persons with dementia. Gerontologist 1995;35:672-8.
96. Kahn D, Gwyther LP, Frances A. Agitation in older persons with dementia: a guide for families and caregivers. Postgraduate Medicine Special Report 1998;286:81-8.
97. Lancôt KL, Best TS, Mittmann N, Liu BA, Oh PI, Einarson TR, et al. Efficacy and safety of neuroleptics in behavioral disorders associated with dementia. J Clin Psychiatry 1998;59:550-61.
98. Devanand DP, Marder K, Michaels KS, Sackeim HA, Bell K, Sullivan MA, et al. A randomized, placebo-controlled dose-comparison trial of haloperidol for psychosis and disruptive behaviors in Alzheimer's disease. Am J Psychiatry 1998;115:1512-20.
99. Katz IR, Jeste DV, Mintzer JE, Clyde C, Napolitano J, Brecher M. Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. J Clin Psychiatry 1999;60:107-15.
100. De Deyn PP, Rabheru K, Rasmussen A, Bocksberger JP, Dautzenberg PLJ, Eriksson S, et al. A randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementia. Neurology 1999;53:946-55.
101. Olin JT, Schneider LS, Katz IR, Meyers BS, Alexopoulos GS, Breitner JC, et al. Provisional diagnostic criteria for depression of Alzheimer disease. Am J Geriatr Psychiatry 2002;10:125-8.
102. Lyketsos CG, Breitner JCS, Rabins PV. An evidence-based proposal for the classification of neuropsychiatric disturbance in Alzheimer's disease. Int J Geriatr Psychiatry 2001;16:1037-42.
103. Lyketsos CG, Olin J. Depression in Alzheimer's disease: overview and treatment. Biol Psychiatry 2002;52:243-52.
104. Lyketsos CG, Sheppard JE, Steele CD, Kopunek S, Steinberg M, Baker AS, et al. Randomized, placebo-controlled, double-blind clinical trial of sertraline in the treatment of depression complicating Alzheimer's disease: initial results from the depression in Alzheimer's disease study. Am J Psychiatry 2000;157:1686-9.
105. Teri L, Logsdon RG, Peskind E, Raskind M, Weiner MF, Tractenberg RE, et al. Treatment of agitation in AD: a randomized, placebo-controlled clinical trial. Ncurology 2000;55:1271-8.
106. Zarit SH, Johansson L, Jarrott SE. Family caregiving: stresses, social programs, and clinical interventions. In: Nordhus IH, VandenBos GR, Bert S, Fromhold P, editors. Clinical geropsychology. Washington, DC: American Psychological Association; 1999. p. 345-60.
107. Kirchhoff KT, Walker L, Hutton A, Spuhler V, Cole BV, Clemmer T. The vortex: families' experiences with death in the intensive care unit. Am J Crit Care 2002;11:200-9.
108. Desbiens NA, Mueller-Rizner N, Vimig B, Lynn J. Stress in caregivers of hospitalized oldest-old patients. J Gerontol Med Sci 2001;56A:M231-5.
109. Seeman TE. Health promoting effects of friends and family on health outcomes in older adults. Am J Health Promot 2000;14:362-70.
110. Hepburn KW, Tomatore J, Center B, Ostwald SW. Dementia family caregiver training: affecting beliefs about caregiving and caregiver outcomes. J Am Geriatr Soc 2001;49:450-7.
111. Wadley V, Haley WE. Diagnostic attributions versus labeling: impact of Alzheimer's disease and major depression diagnoses on emotions, beliefs, and helping intentions of family members. J Gerontol Psychol Sci Soc Sci 2001;56B:244-52.
112. Reynolds CF, Miller MD, Pasternak RE, Frank E, Perel JM, Cornes C, et al. Treatment of bereavement-related major depressive episodes in later life: a controlled study of acute and continuation treatment with nortriptyline and interpersonal psychotherapy. Am J Psychiatry 1999;156:202-8.
113. Prigerson HG, Jacobs SC. Caring for bereaved patients: "All the doctors just suddenly go." JAMA 2001;286:1369-76.