Delirium in the terminally ill

Clinics in Geriatric Medicine

Volumn 16, Issue 2, 2000, Pages 357-372

  Breitbart, William ^a,b,c   Strout, David ^c  

^a Department of Veteran Affairs   (United States)

^b Pain and Palliative Care Service   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC AGENT; BENZODIAZEPINE; CHLORPROMAZINE; HALOPERIDOL; LEVOMEPROMAZINE; LORAZEPAM; MIDAZOLAM; MOLINDONE; NEUROLEPTIC AGENT; OLANZAPINE; PROPOFOL; RISPERIDONE; THIORIDAZINE;

CLINICAL FEATURE; DELIRIUM; DISEASE ASSOCIATION; GERIATRIC DISORDER; HUMAN; RATING SCALE; REVIEW; TERMINAL CARE; TERMINAL DISEASE;

EID: 0034036619     PISSN: 07490690     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0749-0690(05)70061-6     Document Type: Article

References (90)

1. F. Adams F. Fernandez B.S. Anderson Emergency pharmacotherapy of delirium in the critically ill cancer patient Psychosomatics 27 1986 33 37
2. F. Adams J.R. Wuesada J.U. Gutterman Neuropsychiatric manifestations of human leukocyte interferon therapy in patients with cancer JAMA 252 1984 938 941
3. T. Akechi Y. Uchitomi H. Okamura Usage of haloperidol for delirium in cancer patients Support Care Cancer 4 1996 390 392
4. M.S. Albert S.E. Levkoff C. Reilly The delirium symptom interview: An interview for the detection of delirium symptoms in hospitalized patients J Geriatr Psychiatry Neurol 5 1991 14 21
5. American Psychiatric Association Diagnostic and Statistical Manual of mental Disorders ed 4 1994 American Psychiatric Association Washington, DC 122 133
6. American Psychiatric Association Practice Guidelines for the Treatment of Patients with Delirium Am J Psychiatry 156 suppl 1999 1 20
7. R. Baldessarini F. Frankenburg Clozapine: A novel antipsychotic agent N Engl J Med 324 1991 746 752
8. Belzie L: Risperidone for AIDS-Associated dementia: A case series [abstract NR214]. In Programs and Abstracts of the 149th Annual Meeting of the American Psychiatric Association, New York, 1996, pp 1–126
9. K. Berman E.J. Eastham Psychogeriatric ascertainment and assessment for treatment in an acute medical ward setting Aging 3 1974 174 188
10. D.M. Bottomley G.W. Hanks Subcutaneous midazolam infusion in palliative care J Pain Symptom Manage 5 1990 259 261
11. W. Breitbart Psychiatric management of cancer pain Cancer 63 1989 2336 2342
12. W. Breitbart E. Bruera H. Chochinov Neuropsychiatric syndromes and psychological symptoms in patients with advanced cancer J Pain Symptom Manage 10 1995 131 141
13. W. Breitbart H.M. Chochinov S. Passik Psychiatric aspects of palliative care Doyle D. Hanks G.E.C. MacDonald Oxford Textbook of Palliative Medicine ed 2 1998 Oxford University Press New York 933 954
14. W. Breitbart R. Marotta M. Platt A double-blind trial of Haloperidol, Chlorpromazine, and Lorazepan in the treatment of delirium in hospitalized AIDS patients Am J Psychiatry 1996 231 237
15. W. Breitbart B. Rosenfeld A. Roth The memorial delirium assessment scale J Pain Symptom Manage 13 1997 128 137
16. W. Breitbart Psychiatric complications of cancer. In: Current Therapy in Hematology Oncology-3 Brain M.C. Carbone P.P. 1988 B.C. Decker Inc. Toronto and Philadelphia 268 274
17. E. Bruera Case report: Severe organic brain syndrome J Palliat Care 7 1991 36 38
18. E. Bruera R. Fainsinger M.J. Miller The assessment of pain intensity in patients with cognitive failure: A preliminary report J Pain Symptom Manage 7 1992 267 270
19. E. Bruera K. Macmillan J. Hanson The cognitive effects of the administration of narcotic analgesics in patients with cancer pain Pain 39 1989 13 16
20. E. Bruera M.J. Miller J. McCallion Cognitive failure in patients with terminal cancer: A prospective study J Pain Symptom Manage 7 1992 192 195
21. N. Coyle W. Breitbart S. Weaver Delirium as a contributing factor to “Crescendo” pain: Three case reports J Pain Symptom Manage 9 1994 44 47
22. De Sousa E. A. Jepson Midazolam in terminal care Lancet 1 1988 67 68
23. K.D. Denicoff D.R. Rubinow M.Z. Papa The neuropsychiatric effects of treatment with interleukin-w and lymphokine-activated killer cells Ann of Intern Med 107 1987 293 300
24. L.R. Derogatis M. Feldstein G. Morrow A survey of psychotropic drug prescriptions in an oncology population Cancer 44 1979 1919 1929
25. R. Fainsinger E. Bruera Treatment of delirium in a terminally ill patient J Pain Symptom Manage 7 1992 54 56
26. R. Fainsinger C. Young Cognitive failure in a terminally ill patient J Pain Symptom Manage 6 1991 492 494
27. R. Fainsinger T. MacEachern J. Hanson Symptom control during the last week of life in a palliative care unit J Palliat Care 7 1991 5 11
28. F. Fernandez V.F. Holmes F. Adams Treatment of severe refractory agitation with a Haldol drip J Clin Psychiatry 49 1988 239 241
29. F. Fernandez J.F. Levy P.W.A. Mansell Management of delirium in terminally ill AIDS patients Int J Psychiatry Med 19 1989 165 172
30. M.F. Folstein S.E. Folstein P.R. McHugh “Mini-mental status:” A practical method for grading the cognitive state of patients for clinicians J Psychiatr Res 12 1975 189 198
31. M.R. Gillick N.A. Serrel L.S. Gillick Adverse consequences of hospitalization in the elderly Soc Sci Med 16 1982 1033 1038
32. G. Goldberg V. Mor A survey of psychotropic use in terminal cancer patients Psychosomatics 26 1985 745 751
33. H.M. Hodkinson Mental impairment in the elderly J R Coll Physicians Lond 7 1973 305 317
34. Holland J.C. Fassanellows T. Ohnuma Psychiatric symptoms associated with L-asparaginase administration J Psychiatr Res 10 1974 165 179
35. Inouye B.K. Bogardus S.T. Jr P.A. Charpentier A multicomponent intervention to prevent delirium in hospitalized older patients N Engl J Med 1999 669 676
36. B.K. Inouye C.H. Vandyck C.A. Alessi Clarifying confusion: The confusion assessment method, a new method for detection of delirium Ann Inter Med 113 1990 941 948
37. J.C. Jacobs M.R. Bernhard A. Delgado Screening for organic mental syndromes in the medically ill Ann Intern Med 86 1977 40 46
38. H. Jaeger G. Morrow F. Brescia A survey of psychotropic drug utilization by patients with advanced neoplastic disease Gen Hosp Psychiatry 7 1985 353 360
39. R. Katzman T. Brown P. Fuld Validation of a short orientation-memory-concentration test of cognitive impairment Am J Psychiatry 140 1983 734 739
40. E.B. Knight M.F. Folstein Unsuspected emotional and cognitive disturbance in medical patients Ann Intern Med 87 1977 723 724
41. R. Leipzig H. Goodman G. Gray Reversible narcotic associated mental status impairment in patients with metastatic cancer Pharmacology 35 1987 47 54
42. P.M. Levine P. Silberfarb Z.J. Lipowski Mental disorders in cancer patients Cancer 42 1978 1385 1391
43. S. Levkoff B. Liptzin P. Cleary Review of research instruments and techniques used to detect delirium Int Psychogeriatr 3 1992 253 272
44. I. Lichter E. Hunt The last 24 Hours of life J Palliat Care 6 1990 7 15
45. Z.J. Lipowski Delirium: Acute brain failure in man 1980 Charles C Thomas Springfield, IL
46. Lipowski ZJ: Delirium: Acute confusional states. New York, Oxford, 1990
47. Z.J. Lipowski Transient cognitive disorders (delirium, acute confusional states) in the elderly Am J Psychiatry 140 1983 1426 1436
48. M.J. Massie J. Holland E. Glass Delirium in terminally ill cancer patients Am J Psychiatry 140 1983 1048 1050
49. M. Menza G. Murray V. Holmes Controlled study of extrapyramidal reactions in the management of delirious medically ill patients: Intravenous haloperidol versus intravenous haloperidol plus benzodiazepines Heart Lung 17 1988 238 241
50. S. Mercadante F. DeConno C. Ripamonti Propofol in terminal care J Pain Symptom Mange 10 1995 639 642
51. P.S. Miller J.S. Richardson I.A. Jyn Association of low serum anticholinergic levels and cognitive impairment in elderly presurgical patients Am J Psychiatry 145 1988 342 345
52. H. Minagawa Y. Uchitomi S. Yamawaki Psychiatric morbidity in terminally ill cancer patients: A prospective study Cancer 73 1996 1131 1137
53. J. Moyle The use of propofol in palliative medicine J Pain Symptom Manage 10 1995 643 646
54. G.B. Murray Confusion, delirium, and dementia Hackett T.P. Massachusetts General Hospital Handbook of General Hospital Psychiatry ed 2 1987 PSG Publishing Company Littleton, MS 84 115
55. D.J. Oliver The use of Methotrimeprazine in terminal care British Journal of Clinical Practice 39 1985 339 340
56. S.D. Passik M. Cooper Complicated delirium in a cancer patient successfully treated with olanzipine J Pain Symptom Manage 17 1999 219 223
57. J. Pereira J. Hanson E. Bruera The frequency and clinical course of cognitive impairment in patients with terminal cancer Cancer 1997 835 841
58. S.W. Perry Organic mental disorders caused by HIV: Update on early diagnosis and treatment Am J Psychiatry 147 1990 696 710
59. M. Platt W. Breitbart M. Smith Efficacy of neuroleptics for hypoactive delirium [letter] J Neuropsychiatry Clin Neurosci 6 1994 66 67
60. J.B. Posner Delirium and exogenous metabolic brain disease Beeson P.B. McDermott W. Wyngaarden J.B. Cecil Textbook of Medicine 1979 W.B. Saunders Philadelphia 644 651
61. J.H. Rosen Double-blind comparison of haloperidol and thioridazine in geriatric outpatients J Clin Psychiatry 40 1979 17 20
62. C.A. Ross C.E. Peyser I. Shapiro Delirium: Phenomenologic and etiologic subtypes Internal Psychogeriatrics 3 1991 135 147
63. C.A. Ross CNS arousal systems: possible role in delirium Int Psychogeriatr 3 1991 353 371
64. D.J. Seymour P.J. Henschke R.D.T. Cape Acute confusional states and dementia in the elderly: The role of dehydration/volume depletion, physical illness and age Aging 9 1980 137 146
65. P.M. Silberfarb Chemotherapy and cognitive defects in cancer patients Annu Rev Med 34 1983 35 46
66. Singh A: Safety of Risperidone in patients with HIV and AIDS [abstract NR212]. In Programs and Abstract of the 149th Annual meeting of the American Psychiatric Association, New York, 1996, pp 4–9
67. A. Sipahimalani P.S. Massand Olanzipine in the treatment of delirium Psychosomatics 39 1998 422 430
68. A. Sipahimalani R.M. Sime P.S. Masand Treatment of delirium with risperidone International Journal of Geriatric Psychopharmacology 1 1997 24 26
69. G.R. Smith C.W. Taylor P. Linkons Haloperidol versus thioridazine for the treatment of psychogeriatric patients: A double-blind clinical trial Psychosomatics 15 1974 134 138
70. M.J. Smith W.S. Breitbart M.M. Platt A critique of instruments and methods to detect, diagnose, and rate delirium J Pain Symptom Manage 10 1995 35 77
71. F. Stiefel E. Bruera Psychostimulants for hypoactive hypoalert delirium? J Palliat Care 3 1991 25 26
72. F. Stiefel J. Holland Delirium in cancer patients Int Psychogeriatr 3 1991 333 336
73. F. Stiefel W.S. Breitbart J.C. Holland Corticosteroids in cancer: Neuropsychiatric complications Cancer Invest 7 1989 479 491
74. F. Stiefel R. Fainsinger E. Bruera Acute confusional states in patients with advanced cancer J Pain Symptom Manage 7 1992 94 98
75. F. Steifel A. Kornblith J. Holland Changes in prescription patterns of psychotropic drugs for cancer patients during a 10-year period Cancer 1990 1048 1053
76. H. Thomas E. Schwartz R. Petrilli Droperidol versus haloperidol for chemical restraint of agitated and combative patients Ann Emerg Med 21 1992 407 413
77. P.T. Trzepacz R.W. Baker J. Greenhouse A symptom rating scale for delirium Psychiatric Research 1 1988 89 97
78. P.T. Trzepacz G.B. Teague Z.J. Lipowski Delirium and other organic mental disorders in a general hospital Gen Hosp Psychiatry 7 1985 101 106
79. M.M. Tsuang L.M. Lu B.A. Stotsky Haloperidol versus thioridazine for hospitalized psychogeriatrics patients: Double-blind study J Am Geriatr Soc 19 1971 593 600
80. R. Tuma L. DeAngelis Acute encephalopathy in patients with systemic cancer Ann Neurol 32 1992 288 331
81. L.E. Tune Post-operative delirium Int Psychogeriatr 3 1991 325 332
82. R.G. Twycross S.A. Lack Symptom control in far advanced cancer: Pain relief 1983 Pitman Brooks London
83. J. Varsamis T. Zuchowski K.K. Maini Survival rates and causes of death in geriatric psychiatric patients: A six year follow-up study Can Psychiatr Assoc J 17 1972 17 22
84. V. Ventafridda C. Ripamonti F. DeConno Symptom prevalence and control during cancer patients' last days of life J Palliat Care 6 1990 7 11
85. G.A. Warsaw J. Moore S.W. Friedman Functional disability in the hospitalized elderly JAMA 248 1982 847 850
86. W.W. Weddington Delirium and depression associated with amphotericin B Psychosomatics 23 1982 1076 1078
87. M.A. Williams Delirium/acute confusional states: Evaluation devices in nursing International Psychogeriatrics 3 1991 301 308
88. M.G. Wise G.T. Brandt Delirium Yudofsky S.C. Hales R.E. Textbook of Neuropsychiatry ed 2 1992 American Psychiatric Association Washington, DC
89. G. Wolber M. Romaniuk E. Eastman Validity of the short portable mental status questionnaire with elderly psychiatric patients J Consult Clin Psychol 52 1984 712 713
90. D.F. Young Neurological complications of cancer chemotherapy Silverstein A. Neurological Complications of Therapy: Selected Topics 1982 Futura Publishing New York 57 113