Synthesis, structure, and antibacterial activity of 4-imino-1,4-dihydrocinnoline-3-carboxylic acid and 4-oxo-1,4-dihydrocinnoline-3-carboxylic acid derivatives as isosteric analogues of quinolones

Archiv der Pharmazie

Volumn 336, Issue 1, 2003, Pages 18-30

  Stańczak, Andrzej ^a   Ochocki, Zbigniew ^a   Martynowski, Dariusz ^b   Główka, Marek ^b   Nawrot, Ewa ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Antibacterial activity; Cinnolones; Crystal data; DNA topoisomerase; Quinolones

Indexed keywords

1,4 DIHYDRO 4 IMINOQUINOLINE 3 CARBOXYLIC ACID HYDRAZIDE; 1,4 DIHYDRO 4 OXOQUINOLINE 3 CARBOXYLIC ACID HYDRAZIDE; 4 IMINO 1,4 DIHYDROQUINOLINE 3 CARBOXYLIC ACID DERIVATIVE; 4 OXO 1,4 DIHYDROQUINOLINE 3 CARBOXYLIC ACID DERIVATIVE; ANTIINFECTIVE AGENT; DNA TOPOISOMERASE; ETHYL 1,4 DIHYDRO 4 IMINOQUINOLINE 3 CARBOXYLIC ACID; ETHYL 1,4 DIHYDRO 4 OXOQUINOLINE 3 CARBOXYLIC ACID; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; INFRARED SPECTROSCOPY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY DIFFRACTION;

4-QUINOLONES; ANTI-BACTERIAL AGENTS; CARBOXYLIC ACIDS; DNA TOPOISOMERASES, TYPE I; MICROBIAL SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0345701502     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.200390000     Document Type: Article

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