Kinetic and docking studies of the interaction of quinones with the quinone reductase active site

Biochemistry

Volumn 42, Issue 7, 2003, Pages 1985-1994

  Zhou, Zhigang ^b   Fisher, Derek ^a   Spidel, Jared ^a   Greenfield, Jodi ^a   Patson, Brian ^a   Fazal, Aleem ^a   Wigal, Carl ^a   Moe, Owen A ^a   Madura, Jeffry D ^b  

^a LEBANON VALLEY COLLEGE   (United States)

^b DUQUESNE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CORRELATION METHODS; CYTOLOGY; ELECTRONS; REACTION KINETICS; REDUCTION;

BINDING AFFINITY;

ENZYMES;

QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ARTICLE; BINDING AFFINITY; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; ENERGY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME KINETICS; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN INTERACTION; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ANIMALS; ANTHRAQUINONES; BENZOQUINONES; BINDING SITES; FLAVINS; HUMANS; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; NAD(P)H DEHYDROGENASE (QUINONE); NAPHTHOQUINONES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TYROSINE;

EID: 0345270443     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026518s     Document Type: Article

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