Profound loss of T-cell receptor repertoire complexity in cutaneous T-cell lymphoma

Blood

Volumn 102, Issue 12, 2003, Pages 4059-4066

  Yawalkar, Nikhil ^a   Ferenczi, Katalin ^a   Jones, David A ^a   Yamanaka, Keiichi ^a   Suh, Ki Young ^a   Sadat, Sarah ^a   Kupper, Thomas S ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANTIHISTAMINIC AGENT; BEXAROTENE; CALCIPOTRIOL; DENILEUKIN DIFTITOX; DNA; METHOTREXATE; PREDNISONE; STEROID; T LYMPHOCYTE RECEPTOR; TACROLIMUS;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CUTANEOUS T CELL LYMPHOMA; DNA SEQUENCE; ERYTHRODERMA; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; LYMPHOCYTE COUNT; MALE; MYCOSIS FUNGOIDES; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; PSORIASIS; PUVA; SEZARY SYNDROME;

EID: 0345257351     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-04-1044     Document Type: Article

References (42)

1. Ferenczi K, Kupper TS. Cutaneous lymphoma. In: Sober H, ed. Atlas of Clinical Oncology. Hamilton-London: BC Decker; 2000:85-117.
2. Edelson RL. Cutaneous T cell lymphoma: the helping hand of dendritic cells. Ann N Y Acad Sci. 2001;941:1-11.
3. Russell-Jones R, Whittaker S. T-cell receptor gene analysis in the diagnosis of Sezary syndrome. J Am Acad Dermatol. 1999;41:254-249.
4. Rook AH, Gottlieb SL, Wolfe JT, et al. Pathogenesis of cutaneous T-cell lymphoma: implications for the use of recombinant cytokines and photopheresis. Clin Exp Immunol. 1997;107(suppl 1):16-20.
5. Bagot M, Nikolova M, Schirm-Chabanette F, Wechsler J, Boumsell L, Bensussan A. Crosstalk between tumor T lymphocytes and reactive T lymphocytes in cutaneous T cell lymphomas. Ann N Y Acad Sci. 2001;941:31-38.
6. Ferenczi K, Fuhlbrigge RC, Pinkus JL, Pinkus GS, Kupper TS. Increased CCR4 expression in cutaneous T cell lymphoma. J Invest Dermatol. 2002;119:1405-1410.
7. Kim YH, Jensen RA, Watanabe GL, Varghese A, Hoppe RT. Clinical stage IA (limited patch and plaque) mycosis fungoides. A long-term outcome analysis. Arch Dermatol. 1996;132:1309-1313.
8. Scarisbrick JJ, Whittaker S, Evans AV, et al. Prognostic significance of tumor burden in the blood of patients with erythrodermic primary cutaneous T-cell lymphoma. Blood. 2001;97:624-630.
9. Axelrod PI, Lorber B, Vonderheid EC. Infections complicating mycosis fungoides and Sezary syndrome. JAMA. 1992;267:1354-1358.
10. Rook AH, Heald P. The immunopathogenesis of cutaneous T-cell lymphoma. Hematol Oncol Clin North Am. 1995;9:997-1010.
11. Scarisbrick JJ, Child FJ, Evans AV, Fraser-Andrews EA, Spittle M, Russell-Jones R. Secondary malignant neoplasms in 71 patients with Sezary syndrome. Arch Dermatol. 1999;135:1381-1385.
12. Maslanka K, Piatek T, Gorski J, Yassai M. Molecular analysis of T cell repertoires. Spectratypes generated by multiplex polymerase chain reaction and evaluated by radioactivity or fluorescence. Hum Immunol. 1995;44:28-34.
13. Pannetier C, Even J, Kourilsky P. T-cell repertoire diversity and clonal expansions in normal and clinical samples. Immunol Today. 1995;16:176-181.
14. Raaphorst FM, Schelonka RL, Rusnak J, Infante AJ, Teate JM. TCRBV CDR3 diversity of CD4+ and CD8+ T-lymphocytes in HIV-infected individuals. Hum Immunol. 2002;63:51-60.
15. Rieux-Laucat F, Bahadoran P, Brousse N, et al. Highly restricted human T cell repertoire in peripheral blood and tissue-infiltrating lymphocytes in Omenn's syndrome. J Clin Invest. 1998;102:312-321.
16. Signorini S, Pirovano S, Fiorentini S, et al. Restriction of T-cell receptor repertoires in idiopathic CD4+ lymphocytopenia. Br J Haematol. 2000;110:434-437.
17. Wu CJ, Chillemi A, Alyea EP, et al. Reconstitution of T-cell receptor repertoire diversity following T-cell depleted allogeneic bone marrow transplantation is related to hematopoietic chimerism. Blood. 2000;95:352-359.
18. Choi YW, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A. 1989;86:8941-8945.
19. Genevee C, Diu A, Nierat J, et al. An experimentally validated panel of subfamily-specific oligonucleotide primers (V alpha 1-w29/V beta 1-w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction. EurJ Immunol. 1992;22:1261-1269.
20. Moss P, Charmley P, Mulvihill E, et al. The repertoire of T cell antigen receptor beta-chain variable regions associated with psoriasis vulgaris. J Invest Dermatol. 1997;109:14-19.
21. Hall BL, Finn OJ. PCR-based analysis of the T-cell receptor V beta multigene family: experimental parameters affecting its validity. Biotechniques. 1992;13:248-257.
22. Bragado R, Lauzurica P, Lopez D, Lopez de Castro JA. T cell receptor V beta gene usage in a human alloreactive response. Shared structural features among HLA-B27-specific T cell clones. J Exp Med. 1990;171:1189-1204.
23. Hand SL, Alter MD, Finn OJ. T cells receptor beta-chain repertoires are nonrandomly selected in responses to HLA-DR1. Transplantation. 1996;61:1084-1094.
24. Wei S, Charmley P, Robinson MA, Concannon P. The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics. 1994;40:27-36.
25. Pilch H, Hohn H, Freitag K, et al. Improved assessment of T-cell receptor (TCR) VB repertoire in clinical specimens: combination of TCR-CDR3 spectratyping with flow cytometry-based TCR VB frequency analysis. Clin Diagn Lab Immunol. 2002;9:257-266.
26. Beers MH, Berkow R. The Merck Manual of Diagnosis and Therapy. Whitehouse Station, NJ: Merck & Co; 1999:931-938.
27. Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature. 1998;396:643-649.
28. Vogelstein B, Kinzler KW. The multistep nature of cancer. Trends Genet. 1993;9:138-141.
29. Farace F, Orlanducci F, Dietrich PY, et al. T cell repertoire in patients with B chronic lymphocytic leukemia: evidence for multiple in vivo T cell clonal expansions. J Immunol. 1994;153:4281-4290.
30. Kluin-Nelemans JC, Kester MG, Melenhorst JJ, et al. Persistent clonal excess and skewed T-cell repertoire in T cells from patients with hairy cell leukemia. Blood. 1996;87:3795-3802.
31. Vega F, Luthra R, Medeiros LJ, et al. Clonal heterogeneity in mycosis fungoides and its relationship to clinical course. Blood. 1996;100:3369-3373.
32. Tan RS, Butterworth CM, McLaughlin H, Malka S, Samman PD. Mycosis fungoides-a disease of antigen persistence. Br J Dermatol. 1974;91:607-616.
33. Valdimarsson H, Baker BS, Jonsdottir I, Powles A, Fry L. Psoriasis: a T-cell-mediated autoimmune disease induced by streptococcal superantigens? Immunol Today. 1995;16:145-149.
34. Schwab R, Szabo P, Manavalan JS, et al. Expanded CD4+ and CD8+ T cell clones in elderly humans. J Immunol. 1997;158:4493-4499.
35. Posnett DN, Sinha R, Kabak S, Russo C. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammopathy." J Exp Med. 1994;179:609-618.
36. Wack A, Cossarizza A, Heltai S, et al. Age-related modifications of the human alphabeta T cell repertoire due to different clonal expansions in the CD4+ and CD8+ subsets. Int Immunol. 1998;10:1281-1288.
37. Jameson SC. Maintaining the norm: T-cell homeostasis. Nat Rev Immunol. 2002;2:547-556.
38. Hatzakis A, Touloumi G, Karanicolas R, et al. Effect of recent thymic emigrants on progression of HIV-1 disease. Lancet. 2000;355:599-604.
39. McCormack JE, Callahan JE, Kappler J, Marrack PC. Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen. J Immunol. 1993;150:3785-3792.
40. Jackow CM, Cather JC, Hearne V, Asano AT, Musser JM, Duvic M. Association of erythrodermic cutaneous T-cell lymphoma, superantigen-positive Staphylococcus aureus, and oligoclonal T-cell receptor V beta gene expansion. Blood. 1997;89:32-40.
41. Pancake BA, Zucker-Franklin D, Coutavas EE. The cutaneous T cell lymphoma, mycosis fungoides, is a human T cell lymphotropic virus-associated disease: a study of 50 patients. J Clin Invest. 1995;95:547-554.
42. Bazarbachi A, Soriano V, Pawson R, et al. Mycosis fungoides and Sezary syndrome are not associated with HTLV-I infection: an international study. Br J Haematol. 1997;98:927-933.