Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-Chemokine Receptor 3 antagonists

American Journal of Respiratory and Critical Care Medicine

Volumn 165, Issue 12, 2002, Pages 1602-1609

  Bryan, Shannon A ^a,b   Jose, Peter J ^a,b   Topping, Joanna R ^a,b   Wilhelm, Robert ^a,b   Soderberg, Carol ^a,b   Kertesz, Denis ^a,b   Barnes, Peter J ^a,b   Williams, Timothy J ^a,b   Hansel, Trevor T ^a,b   Sabroe, Ian ^a,b,c  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b ROCHE BIOSCIENCE   (United States)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Antagonist; Basophil; Chemokine; Eosinophil

Indexed keywords

CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR3 ANTAGONIST; EOTAXIN; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 4; RO 116 4875 608; RO 116 9132 238; RO 320 2947 001; RO 330 0802 001; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; ASTHMA; EOSINOPHIL; GRANULOCYTE; HUMAN; HUMAN CELL; INFLAMMATION; INTERNALIZATION; LEUKOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING;

CHEMOKINES, CC; CHEMOTAXIS, LEUKOCYTE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION; DUFFY BLOOD-GROUP SYSTEM; EOSINOPHILS; HUMANS; LEUKOCYTES; RECEPTORS, CHEMOKINE; REFERENCE VALUES; UP-REGULATION;

EID: 0037097992     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200111-059OC     Document Type: Article

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