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Volumn 144, Issue 12, 2003, Pages 5293-5299

Dual Effects of Pituitary Adenylate Cyclase-Activating Polypeptide and Isoproterenol on Lipid Metabolism and Signaling in Primary Rat Adipocytes

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; INSULIN; ISOPRENALINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N CYCLOHEXYL 4 (1,2 DIHYDRO 2 OXO 6 QUINOLYLOXY) N (2 HYDROXYETHYL)BUTYRAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHODIESTERASE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE INHIBITOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 0344825828     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0364     Document Type: Article
Times cited : (31)

References (45)
  • 1
    • 0034511574 scopus 로고    scopus 로고
    • The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily
    • Sherwood NM, Krueckl SL, McRory JE 2000 The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily. Endocr Rev 21:619-670
    • (2000) Endocr Rev , vol.21 , pp. 619-670
    • Sherwood, N.M.1    Krueckl, S.L.2    McRory, J.E.3
  • 3
    • 0025075727 scopus 로고
    • Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase-activating polypeptide with 38 residues (PACAP38)
    • Miyata A, Jiang L, Dahl RD, Kitada C, Kubo K, Fujino M, Minamino N, Arimura A 1990 Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase-activating polypeptide with 38 residues (PACAP38). Biochem Biophys Res Commun 170:643-648
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 643-648
    • Miyata, A.1    Jiang, L.2    Dahl, R.D.3    Kitada, C.4    Kubo, K.5    Fujino, M.6    Minamino, N.7    Arimura, A.8
  • 5
    • 0034048147 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide and its receptors: From structure to functions
    • Vaudry D, Gonzalez BJ, Basille M, Yon L, Fournier A, Vaudry H 2000 Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions. Pharmacol Rev 52:269-324
    • (2000) Pharmacol Rev , vol.52 , pp. 269-324
    • Vaudry, D.1    Gonzalez, B.J.2    Basille, M.3    Yon, L.4    Fournier, A.5    Vaudry, H.6
  • 6
    • 0032143876 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) a gut hormone of potential interest in the treatment of diabetes
    • Ahrén B 1998 Glucagon-like peptide-1 (GLP-1) a gut hormone of potential interest in the treatment of diabetes. Bioessays 20:642-651
    • (1998) Bioessays , vol.20 , pp. 642-651
    • Ahrén, B.1
  • 7
    • 0035461315 scopus 로고    scopus 로고
    • The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function
    • Filipsson K, Kvist-Reimer M, Ahrén B 2001 The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function. Diabetes 50:1959-1969
    • (2001) Diabetes , vol.50 , pp. 1959-1969
    • Filipsson, K.1    Kvist-Reimer, M.2    Ahrén, B.3
  • 8
    • 0026718852 scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP): Occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse
    • Fridolf T, Sundler F, Ahrén B 1992 Pituitary adenylate cyclase-activating polypeptide (PACAP): occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse. Cell Tissue Res 269:275-279
    • (1992) Cell Tissue Res , vol.269 , pp. 275-279
    • Fridolf, T.1    Sundler, F.2    Ahrén, B.3
  • 9
    • 0031837626 scopus 로고    scopus 로고
    • PACAP and PACAP receptors in insulin producing tissues: Localization and effects
    • Filipsson K, Sundler F, Hannibal J, Ahrén B 1998 PACAP and PACAP receptors in insulin producing tissues: localization and effects. Regul Pept 74:167-175
    • (1998) Regul Pept , vol.74 , pp. 167-175
    • Filipsson, K.1    Sundler, F.2    Hannibal, J.3    Ahrén, B.4
  • 10
    • 0030800506 scopus 로고    scopus 로고
    • PACAP(1-38) as neurotransmitter in pig pancreas: Receptor activation revealed by the antagonist PACAP-(6-38)
    • Tornoe K, Hannibal J, Fahrenkrug J, Holst JJ 1997 PACAP(1-38) as neurotransmitter in pig pancreas: receptor activation revealed by the antagonist PACAP-(6-38). Am J Physiol 273:G436-G446
    • (1997) Am J Physiol , vol.273
    • Tornoe, K.1    Hannibal, J.2    Fahrenkrug, J.3    Holst, J.J.4
  • 12
    • 0344908216 scopus 로고    scopus 로고
    • Signaling mechanisms underlying the insulinotropic effect of pituitary adenylate cyclase-activating polypeptide in HIT-T15 cells
    • Klinteberg KA, Karlsson S, Ahrén B 1996 Signaling mechanisms underlying the insulinotropic effect of pituitary adenylate cyclase-activating polypeptide in HIT-T15 cells. Endocrinology 137:2791-2798
    • (1996) Endocrinology , vol.137 , pp. 2791-2798
    • Klinteberg, K.A.1    Karlsson, S.2    Ahrén, B.3
  • 13
    • 0032484208 scopus 로고    scopus 로고
    • + to the insulinotropic action of PACAP 38 in HIT-T15 cells
    • + to the insulinotropic action of PACAP 38 in HIT-T15 cells. J Biol Chem 273:32602-32607
    • (1998) J Biol Chem , vol.273 , pp. 32602-32607
    • Filipsson, K.1    Karlsson, S.2    Ahrén, B.3
  • 14
    • 0034791010 scopus 로고    scopus 로고
    • Targeted disruption of the pituitary adenylate cyclase-activating polypeptide gene results in early postnatal death associated with dysfunction of lipid and carbohydrate metabolism
    • Gray SL, Cummings KJ, Jirik FR, Sherwood NM 2001 Targeted disruption of the pituitary adenylate cyclase-activating polypeptide gene results in early postnatal death associated with dysfunction of lipid and carbohydrate metabolism. Mol Endocrinol 15:1739-1747
    • (2001) Mol Endocrinol , vol.15 , pp. 1739-1747
    • Gray, S.L.1    Cummings, K.J.2    Jirik, F.R.3    Sherwood, N.M.4
  • 15
    • 0032822995 scopus 로고    scopus 로고
    • Insulinotropin PACAP potentiates insulin-stimulated glucose uptake in 3T3-L1 cells
    • Nakata M, Shioda S, Oka Y, Maruyama I, Yada T 1999 Insulinotropin PACAP potentiates insulin-stimulated glucose uptake in 3T3-L1 cells. Peptides 20:943-948
    • (1999) Peptides , vol.20 , pp. 943-948
    • Nakata, M.1    Shioda, S.2    Oka, Y.3    Maruyama, I.4    Yada, T.5
  • 17
    • 0028033522 scopus 로고
    • Glycogenolytic activity of pituitary adenylate-cyclase activating polypeptide (PACAP) in vivo and in vitro
    • Sekiguchi Y, Kasai K, Hasegawa K, Suzuki Y, Shimoda S 1994 Glycogenolytic activity of pituitary adenylate-cyclase activating polypeptide (PACAP) in vivo and in vitro. Life Sci 55:1219-1228
    • (1994) Life Sci , vol.55 , pp. 1219-1228
    • Sekiguchi, Y.1    Kasai, K.2    Hasegawa, K.3    Suzuki, Y.4    Shimoda, S.5
  • 19
    • 0022340107 scopus 로고
    • cAMP-dependent protein kinase and lipolysis in rat adipocytes
    • Honnor RC, Dhillon GS, Londos C 1985 cAMP-dependent protein kinase and lipolysis in rat adipocytes. J Biol Chem 260:15130-15138
    • (1985) J Biol Chem , vol.260 , pp. 15130-15138
    • Honnor, R.C.1    Dhillon, G.S.2    Londos, C.3
  • 20
    • 0022337919 scopus 로고
    • cAMP-dependent protein kinase and lipolysis in rat adipocytes
    • Londos C, Honnor RC, Dhillon GS 1985 cAMP-dependent protein kinase and lipolysis in rat adipocytes. J Biol Chem 260:15139-15145
    • (1985) J Biol Chem , vol.260 , pp. 15139-15145
    • Londos, C.1    Honnor, R.C.2    Dhillon, G.S.3
  • 21
    • 0030957594 scopus 로고    scopus 로고
    • Structure, localization and regulation of cGMP-inhibited phosphodiesterase (PDE3)
    • Degerman E, Belfrage P, Manganiello V 1997 Structure, localization and regulation of cGMP-inhibited phosphodiesterase (PDE3). J Biol Chem 272:6823-6826
    • (1997) J Biol Chem , vol.272 , pp. 6823-6826
    • Degerman, E.1    Belfrage, P.2    Manganiello, V.3
  • 23
    • 0028018097 scopus 로고
    • Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes. Studies using the selective inhibitor wortmannin
    • Rahn T, Ridderstråle M, Tornqvist H, Manganiello V, Fredriksson G, Belfrage P, Degerman E 1994 Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes. Studies using the selective inhibitor wortmannin. FEBS Lett 350:314-318
    • (1994) FEBS Lett , vol.350 , pp. 314-318
    • Rahn, T.1    Ridderstråle, M.2    Tornqvist, H.3    Manganiello, V.4    Fredriksson, G.5    Belfrage, P.6    Degerman, E.7
  • 24
    • 85011468695 scopus 로고    scopus 로고
    • Insulin-induced phosphorylation and activation of phosphodiesterase 3B in rat adipocytes: Possible role for protein kinase B but not mitogen-activated protein kinase or p70 S6 kinase
    • Wijkander J, Rahn Landström T, Manganiello V, Belfrage P, Degerman E 1998 Insulin-induced phosphorylation and activation of phosphodiesterase 3B in rat adipocytes: possible role for protein kinase B but not mitogen-activated protein kinase or p70 S6 kinase. Endocrinology 139:219-227
    • (1998) Endocrinology , vol.139 , pp. 219-227
    • Wijkander, J.1    Rahn Landström, T.2    Manganiello, V.3    Belfrage, P.4    Degerman, E.5
  • 26
    • 0034192086 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells
    • Ahmad F, Cong L, Stenson Holst L, Wang L, Rahn Landström T, Pierce JH, Quon MJ, Degerman E, Manganiello VC 2000 Cyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells. J Immunol 164:4678-4688
    • (2000) J Immunol , vol.164 , pp. 4678-4688
    • Ahmad, F.1    Cong, L.2    Stenson Holst, L.3    Wang, L.4    Rahn Landström, T.5    Pierce, J.H.6    Quon, M.J.7    Degerman, E.8    Manganiello, V.C.9
  • 27
    • 0030187992 scopus 로고    scopus 로고
    • Distribution of GLP-1 and PACAP receptors in human tissues
    • Wei Y, Mojsov S 1996 Distribution of GLP-1 and PACAP receptors in human tissues. Acta Physiol Scand 157:355-357
    • (1996) Acta Physiol Scand , vol.157 , pp. 355-357
    • Wei, Y.1    Mojsov, S.2
  • 28
    • 0022366558 scopus 로고
    • cAMP-dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation, and predictability in behavior
    • Honnor RC, Dhillon GS, Londos CJ 1985 cAMP-dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation, and predictability in behavior. J Biol Chem 260:15122-15129
    • (1985) J Biol Chem , vol.260 , pp. 15122-15129
    • Honnor, R.C.1    Dhillon, G.S.2    Londos, C.J.3
  • 29
    • 4344639664 scopus 로고
    • Microdetermination of long-chain fatty acids in plasma and tissues
    • Dole V, Neinertz H 1960 Microdetermination of long-chain fatty acids in plasma and tissues. J Biol Chem 235:2595-2599
    • (1960) J Biol Chem , vol.235 , pp. 2595-2599
    • Dole, V.1    Neinertz, H.2
  • 31
    • 0021822478 scopus 로고
    • Antilipolytic action of insulin: Role of cAMP phosphodiesterase activation
    • Elks ML, Manganiello V 1985 Antilipolytic action of insulin: Role of cAMP phosphodiesterase activation. Endocrinology 116:2119-2121
    • (1985) Endocrinology , vol.116 , pp. 2119-2121
    • Elks, M.L.1    Manganiello, V.2
  • 33
    • 0034130748 scopus 로고    scopus 로고
    • Synergism between insulin and low concentrations of isoproterenol in the stimulation of leptin release by cultured human adipose tissue
    • Fain JN, Cowan Jr GS, Buffington C, Li J, Pouncey L, Bahouth SW 2000 Synergism between insulin and low concentrations of isoproterenol in the stimulation of leptin release by cultured human adipose tissue. Metabolism 49:804-809
    • (2000) Metabolism , vol.49 , pp. 804-809
    • Fain, J.N.1    Cowan Jr., G.S.2    Buffington, C.3    Li, J.4    Pouncey, L.5    Bahouth, S.W.6
  • 34
    • 0027930436 scopus 로고
    • PI-3-kinase inhibitor wortmannin blocks the insulin-like effects of growth hormone in isolated rat adipocytes
    • Ridderstråle M, Tornqvist H 1994 PI-3-kinase inhibitor wortmannin blocks the insulin-like effects of growth hormone in isolated rat adipocytes. Biochem Biophys Res Commun 203:306-310
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 306-310
    • Ridderstråle, M.1    Tornqvist, H.2
  • 35
    • 0034464742 scopus 로고    scopus 로고
    • Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
    • Gether U 2000 Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr Rev 21:90-113
    • (2000) Endocr Rev , vol.21 , pp. 90-113
    • Gether, U.1
  • 37
    • 0035920122 scopus 로고    scopus 로고
    • β-Adrenergic activation of p38 MAP kinase in adipocytes
    • Cao W, Mededev AV, Daniel KW, Collins S 2001 β-Adrenergic activation of p38 MAP kinase in adipocytes. J Biol Chem 276:27077-27082
    • (2001) J Biol Chem , vol.276 , pp. 27077-27082
    • Cao, W.1    Mededev, A.V.2    Daniel, K.W.3    Collins, S.4
  • 39
    • 0026560834 scopus 로고
    • Lipolytic action of glucagon-like peptides in isolated rat adipocytes
    • Ruiz-Grande C, Alarcon C, Merida E, Valverde I 1992 Lipolytic action of glucagon-like peptides in isolated rat adipocytes. Peptides 13:13-16
    • (1992) Peptides , vol.13 , pp. 13-16
    • Ruiz-Grande, C.1    Alarcon, C.2    Merida, E.3    Valverde, I.4
  • 41
    • 0035044628 scopus 로고    scopus 로고
    • Action of glucagon and glucagon-like peptide-1-(7-36) amide on lipolysis in human subcutaneous adipose tissue and skeletal muscle in vivo
    • Bertin E, Arner P, Bolinder J, Hagström-Toft E 2001 Action of glucagon and glucagon-like peptide-1-(7-36) amide on lipolysis in human subcutaneous adipose tissue and skeletal muscle in vivo. J Clin Endocrinol Metab 86:1229-1234
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1229-1234
    • Bertin, E.1    Arner, P.2    Bolinder, J.3    Hagström-Toft, E.4
  • 42
    • 0030884317 scopus 로고    scopus 로고
    • Novel signal transduction and peptide specificity of glucagon-like peptide receptor in 3T3-L1 adipocytes
    • Montrose-Rafizadeh C, Yang H, Wang Y, Roth J, Montrose MH, Adams LG 1997 Novel signal transduction and peptide specificity of glucagon-like peptide receptor in 3T3-L1 adipocytes. J Cell Physiol 172:275-283
    • (1997) J Cell Physiol , vol.172 , pp. 275-283
    • Montrose-Rafizadeh, C.1    Yang, H.2    Wang, Y.3    Roth, J.4    Montrose, M.H.5    Adams, L.G.6
  • 44
    • 0033520869 scopus 로고    scopus 로고
    • GIP biology and fat metabolism
    • Yip RGC, Wolfe MM 2000 GIP biology and fat metabolism. Life Sci 66:91-103
    • (2000) Life Sci , vol.66 , pp. 91-103
    • Yip, R.G.C.1    Wolfe, M.M.2
  • 45
    • 0030953398 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans
    • Filipsson K, Tornoe K, Holst JJ, Ahrén B 1997 Pituitary adenylate cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans. J Clin Endocrinol Metab 82:3093-3098
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3093-3098
    • Filipsson, K.1    Tornoe, K.2    Holst, J.J.3    Ahrén, B.4


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