메뉴 건너뛰기




Volumn 20, Issue 8, 1999, Pages 943-948

Insulinotropin PACAP potentiates insulin-stimulated glucose uptake in 3T3 L1 cells

Author keywords

3T3 L1; Adipocyte; Glucose uptake; Insulin; PAC1 receptor; PACAP; PI 3 kinase; Tyrosine phosphorylation

Indexed keywords

DEOXYGLUCOSE; GLUCOSE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 0032822995     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(99)00085-6     Document Type: Article
Times cited : (30)

References (28)
  • 1
    • 0028905951 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: Neuroendocrine and endocrine interactions
    • Arimura A., Shioda S. pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors neuroendocrine and endocrine interactions . Front Neuroendocrinol. 16:1995;53-88.
    • (1995) Front Neuroendocrinol , vol.16 , pp. 53-88
    • Arimura, A.1    Shioda, S.2
  • 2
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
    • Cheatham B., Vlahos C.J., Cheatham L., Wang L., Blenis J., Kahn C.R. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol. 14:1994;4902-4911.
    • (1994) Mol Cell Biol , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 3
    • 0028077525 scopus 로고
    • Glucagon-like peptide-1(7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: One of several potential extrapancreatic sites of GLP-1 action
    • Egan J.M., Monterose-Rafizadeh C., Wang Y., Bernier M., Roth J. Glucagon-like peptide-1(7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes one of several potential extrapancreatic sites of GLP-1 action . Endocrinology. 135:1994;2070-2075.
    • (1994) Endocrinology , vol.135 , pp. 2070-2075
    • Egan, J.M.1    Monterose-Rafizadeh, C.2    Wang, Y.3    Bernier, M.4    Roth, J.5
  • 4
    • 0031832016 scopus 로고    scopus 로고
    • PACAP stimulates insulin secretion but inhibits insulin sensitivity in mice
    • Filipsson K., Pacini G., Scheurink A.J.W., Ahren B. PACAP stimulates insulin secretion but inhibits insulin sensitivity in mice. Am J Physiol. 274:1998;E834-E842.
    • (1998) Am J Physiol , vol.274
    • Filipsson, K.1    Pacini, G.2    Scheurink, A.J.W.3    Ahren, B.4
  • 5
    • 0031837626 scopus 로고    scopus 로고
    • PACAP and PACAP receptors in insulin producing tissues: Localization and effects
    • Filipsson K., Sundler F., Hannibal J., Ahren B. PACAP and PACAP receptors in insulin producing tissues localization and effects . Regul Pept. 74:1998;167-175.
    • (1998) Regul Pept , vol.74 , pp. 167-175
    • Filipsson, K.1    Sundler, F.2    Hannibal, J.3    Ahren, B.4
  • 6
    • 0026718852 scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP): Occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse
    • Fridolf T., Sundler F., Ahren B. Pituitary adenylate cyclase-activating polypeptide (PACAP) occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse . Cell Tissue Res. 269:1992;275-279.
    • (1992) Cell Tissue Res , vol.269 , pp. 275-279
    • Fridolf, T.1    Sundler, F.2    Ahren, B.3
  • 7
    • 0026596851 scopus 로고
    • Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus
    • Gutniak M., Orskov C., Holst J.J., Ahren B., Efendic S. Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus. N Engl J Med. 326:1992;1316-1322.
    • (1992) N Engl J Med , vol.326 , pp. 1316-1322
    • Gutniak, M.1    Orskov, C.2    Holst, J.J.3    Ahren, B.4    Efendic, S.5
  • 9
    • 0028351892 scopus 로고
    • Cloning and functional characterization of a third pituitary adenylate cyclase-activating polypeptide receptor subtype expressed in insulin-secreting cells
    • Inagaki N., Yoshida H., Mizuta M., Mizuno N., Fujii Y., Gonoi T., Miyazaki J., Seino S. Cloning and functional characterization of a third pituitary adenylate cyclase-activating polypeptide receptor subtype expressed in insulin-secreting cells. Proc Natl Acad Sci USA. 91:1994;2679-2683.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2679-2683
    • Inagaki, N.1    Yoshida, H.2    Mizuta, M.3    Mizuno, N.4    Fujii, Y.5    Gonoi, T.6    Miyazaki, J.7    Seino, S.8
  • 10
    • 0026511295 scopus 로고
    • Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide
    • Ishihara T., Shigemoto R., Mori K., Takahashi K., Nagata S. Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide. Neuron. 8:1992;811-819.
    • (1992) Neuron , vol.8 , pp. 811-819
    • Ishihara, T.1    Shigemoto, R.2    Mori, K.3    Takahashi, K.4    Nagata, S.5
  • 11
    • 0026542016 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide stimulates insulin release from isolated perfused rat pancreas
    • Kawai K., Ohse C., Watanabe Y., Suzuki S., Yamashita K., Ohashi S. Pituitary adenylate cyclase activating polypeptide stimulates insulin release from isolated perfused rat pancreas. Life Sciences. 50:1992;257-261.
    • (1992) Life Sciences , vol.50 , pp. 257-261
    • Kawai, K.1    Ohse, C.2    Watanabe, Y.3    Suzuki, S.4    Yamashita, K.5    Ohashi, S.6
  • 12
    • 0344908216 scopus 로고    scopus 로고
    • Signaling mechanisms underlying the insulinotropic effect of pituitary adenylate cyclase-activating polypeptide in HIT-T15 cells
    • Klinteberg K., Karlsson S., Ahren B. Signaling mechanisms underlying the insulinotropic effect of pituitary adenylate cyclase-activating polypeptide in HIT-T15 cells. Endocrinology. 137:1996;2791-2798.
    • (1996) Endocrinology , vol.137 , pp. 2791-2798
    • Klinteberg, K.1    Karlsson, S.2    Ahren, B.3
  • 13
    • 0030869757 scopus 로고    scopus 로고
    • Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110 beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide
    • Kurosu H., Maehama T., Okada T., Yamamoto T., Hoshino S., Fukui Y., Ui M., Hazeki O., Katada T. Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110 beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide. J Biol Chem. 272:1997;24252-24256.
    • (1997) J Biol Chem , vol.272 , pp. 24252-24256
    • Kurosu, H.1    Maehama, T.2    Okada, T.3    Yamamoto, T.4    Hoshino, S.5    Fukui, Y.6    Ui, M.7    Hazeki, O.8    Katada, T.9
  • 14
    • 0031417185 scopus 로고    scopus 로고
    • Specific antibody recognition of rat pituitary adenylate cyclase activating polypeptide receptors
    • Li M., Shioda S., Somogyvari, Vigh A., Onda H., Arimura A. Specific antibody recognition of rat pituitary adenylate cyclase activating polypeptide receptors. Endocrine. 7:1997;183-190.
    • (1997) Endocrine , vol.7 , pp. 183-190
    • Li, M.1    Shioda, S.2    Somogyvari3    Vigh, A.4    Onda, H.5    Arimura, A.6
  • 15
    • 0027332401 scopus 로고
    • The VIP2 receptor: Molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide
    • Lutz E.M., Sheward W.J., West K.M., Morrow J.A., Flnk G., Harmer A.J. The VIP2 receptor molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide . FEBS Lett. 334:1993;3-8.
    • (1993) FEBS Lett , vol.334 , pp. 3-8
    • Lutz, E.M.1    Sheward, W.J.2    West, K.M.3    Morrow, J.A.4    Flnk, G.5    Harmer, A.J.6
  • 17
    • 0030025047 scopus 로고    scopus 로고
    • Insulin action impaired by deficiency of the G-protein subunit Gi alpha2
    • Moxham C.M., Malbon C.C. Insulin action impaired by deficiency of the G-protein subunit Gi alpha2. Nature (London). 379:1996;840-844.
    • (1996) Nature (London) , vol.379 , pp. 840-844
    • Moxham, C.M.1    Malbon, C.C.2
  • 18
    • 0030035099 scopus 로고    scopus 로고
    • Synergistic activation of PtdIns 3-kinase by tyrosine-phosphorylated peptide and beta γ-subunits of GTP-binding proteins
    • Okada T., Hazeki O., Ui M., Katada T. Synergistic activation of PtdIns 3-kinase by tyrosine-phosphorylated peptide and beta γ-subunits of GTP-binding proteins. Biochem J. 317:1996;475-480.
    • (1996) Biochem J , vol.317 , pp. 475-480
    • Okada, T.1    Hazeki, O.2    Ui, M.3    Katada, T.4
  • 19
    • 0030789699 scopus 로고    scopus 로고
    • Localization and gene expression of the receptor for pituitary adenylate cyclase-activating polypeptide in the rat brain
    • Shioda S., Shuto Y., Somogyvari Vigh A., Legradi G., Onda H., Coy D.H., Nakajo S., Arimura A. Localization and gene expression of the receptor for pituitary adenylate cyclase-activating polypeptide in the rat brain. Neurosci Res. 28:1997;345-354.
    • (1997) Neurosci Res , vol.28 , pp. 345-354
    • Shioda, S.1    Shuto, Y.2    Somogyvari Vigh, A.3    Legradi, G.4    Onda, H.5    Coy, D.H.6    Nakajo, S.7    Arimura, A.8
  • 22
    • 0030030660 scopus 로고    scopus 로고
    • A wortmannin-sensitive signal transduction pathway is involved in the stimulation of insulin release by vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide
    • Straub S.G., Sharp G.W.G. A wortmannin-sensitive signal transduction pathway is involved in the stimulation of insulin release by vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide. J Biol Chem. 271:1996;1660-1668.
    • (1996) J Biol Chem , vol.271 , pp. 1660-1668
    • Straub, S.G.1    Sharp, G.W.G.2
  • 24
    • 0028054862 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet β-cells
    • Yada T., Sakurada M., Ihida K., Nakata M., Murata F., Arimura A., Kikuchi M. Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet β-cells. J Biol Chem. 269:1994;1290-1293.
    • (1994) J Biol Chem , vol.269 , pp. 1290-1293
    • Yada, T.1    Sakurada, M.2    Ihida, K.3    Nakata, M.4    Murata, F.5    Arimura, A.6    Kikuchi, M.7
  • 25
    • 0031449347 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats
    • Yada T., Sakurada M., Ishihara H., Nakata M., Shioda S., Yaekura K., Hamakawa N., Yanagida K., Kikuchi M., Oka Y. Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats. J Physiol (London). 505:1997;319-328.
    • (1997) J Physiol (London) , vol.505 , pp. 319-328
    • Yada, T.1    Sakurada, M.2    Ishihara, H.3    Nakata, M.4    Shioda, S.5    Yaekura, K.6    Hamakawa, N.7    Yanagida, K.8    Kikuchi, M.9    Oka, Y.10
  • 26
    • 0032431082 scopus 로고    scopus 로고
    • Autocrine action of PACAP in islets augments glucose-induced insulin secretion
    • Yada T., Sakurada M., Nakata M., Shioda S., Yaekura K., Kikuchi M. Autocrine action of PACAP in islets augments glucose-induced insulin secretion. Ann NY Acad Sci. 865:1998;451-457.
    • (1998) Ann NY Acad Sci , vol.865 , pp. 451-457
    • Yada, T.1    Sakurada, M.2    Nakata, M.3    Shioda, S.4    Yaekura, K.5    Kikuchi, M.6
  • 27
    • 0030479243 scopus 로고    scopus 로고
    • Current status of PACAP as a regulator of insulin secretion in pancreatic islets
    • Yada T., Sakurada M., Nakata M., Yaekura K., Kikuchi M. Current status of PACAP as a regulator of insulin secretion in pancreatic islets. Ann NY Acad Sci. 805:1996;329-342.
    • (1996) Ann NY Acad Sci , vol.805 , pp. 329-342
    • Yada, T.1    Sakurada, M.2    Nakata, M.3    Yaekura, K.4    Kikuchi, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.