PACAP and PACAP receptors in insulin producing tissues: Localization and effects

Regulatory Peptides

Volumn 74, Issue 2-3, 1998, Pages 167-175

  Filipsson, K ^a   Sundler, F ^b   Hannibal, J ^c   Ahren B ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c BISPEBJERG HOSPITAL   (Denmark)

Author keywords

HIT T15 cells; Insulin secretion; Mouse Pancreas; Rat pancreas; RINm5F cells

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOCRINE CELL; FEMALE; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR OCCUPANCY;

ANIMALS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; IN SITU HYBRIDIZATION; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; NEUROPEPTIDES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I; RECEPTORS, PITUITARY HORMONE; TUMOR CELLS, CULTURED;

EID: 0031837626     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(98)00037-8     Document Type: Article

References (44)

1. Malaisse W.J., Malaisse-Lagae F. The role of cyclic AMP in insulin release. Experentia. 40:1984;1068-1075.
2. Pipeleers DG, Schuit FC, IntVeld PA, Maes E, EL, H-P, Van De Winkel M, Gepts W. Interplay of nutrients and hormones in the regulation of insulin release. Endocrinology 1985;117:824-33.
3. Schuit F.C., Pipeleers D.G. Regulation of adenosine 3′,5′-monophosphate levels in the pancreatic B cell. Endocrinology. 117:1985;834-840.
4. Eizirik D.L., Sandler S., Welsh N., Hellerström C. Preferential reduction of insulin production in mouse pancreatic islets maintained in culture after streptozotocin exposure. Endocrinology. 122:1988;1242-1249.
5. Abdel-Halim S.M., Guenifi A., Khan A., Larsson O., Berggren P.O., Östenson C.G., Efendic S. Impaired coupling of glucose signal to the exocytotic machinery in diabetic GK rats. A defect ameliorated by cAMP. Diabetes. 45:1996;934-940.
6. Schuit F.C. Factors determining the glucose sensitivity and glucose responsiveness of pancreatic beta cells. Hormone Res. 46:1996;99-106.
7. Gutniak M., Ørskov C., Holst J., Ahrén B., Efendic S. Antidiabetogenic effect of glucagon-like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus. N Engl J Med. 326:1992;1316-1322.
8. Ahrén B, Östensson C-G, Efendic S. Other islet peptides. In: Samols E, editor. The Endocrine Pancreas. New York: Raven Press, 1991:153-73.
9. Ahrén B., Taborsky G.J.J., Porte D.J. Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion. Diabetologia. 29:1986;827-836.
10. Sundler F, Böttcher G. Islet innervation, with special reference to neuropeptides. In: Samols E, editor. The Endocrine Pancreas. New York: Raven Press, 1991:29-52.
11. Fridolf T., Sundler F., Ahrén B. Pituitary adenylate cyclase activating polypeptide (PACAP): occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse. Cell Tissue Res. 269:1992;275-279.
12. af Klinteberg K., Karlsson S., Ahrén B. Signaling mechanisms underlying the insulinotropic effect of pituitary adenylate cyclase-activating polypeptide in HIT-T15 cells. Endocrinology. 137:1996;2791-2798.
13. Miyata A., Arimura A., Dalil R.R., Minamino N., Uehara A., Jiang L., Culler M.D., Coy D.H. Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem Biophys Res Commun. 164:1989;567-574.
14. Miyata A., Jiang L., Dahl R.R., Kitada C., Kubo K., Fujino M., Minamino N., Arimura A. Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38). Biochem Biophys Res Commun. 170:1990;643-648.
15. Köves K., Arimura A., Somogyvári-Vigh A., Vigh S., Miller J. Immunohistochemical demonstration of a novel hypothalamic peptide, pituitary adenylate cyclase activating-polypeptide. Endocrinology. 127:1990;264-271.
16. Hannibal J., Mikkelsen J.D., Claisen H., Holst J.J., Wulff B.S., Fahrenkrug J. Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus. Regul Pept. 55:1995;133-148.
17. Arimura A., Somogyvári-Vigh A., Miyata A., Mizuno K., Coy D.H., Kitada C. Tissue distribution of PACAP as determined by RIA: Highly abundant in the rat brain and testes. Endocrinology. 129:1991;2787-2789.
18. Sundler F., Ekblad E., Absood A., Håkanson R., Köves K., Arimura A. Pituitary adenylate cyclase activating peptide: a novel vasoactive intestinal peptide-like neuropeptide in the gut. Neuroscience. 46:1992;439-454.
19. Uddman R., Luts A., Arimura A., Sundler F. Pituitary adenylate cyclase-activating polypeptide (PACAP), a new vasoactive intestinal peptide (VIP)-like peptide in the respiratory tract. Cell Tissue Res. 265:1991;197-201.
20. Shioda S., Legradi G., Leung W.C., Nakajo S., Nakaya K., Arimura A. Localization of pituitary adenylate cyclase-activating polypeptide and its messenger ribonucleic acid in the rat testis by light and electronic microscopic immunocytochemistry and in situ hybridization. Endocrinology. 135:1995;818-825.
21. Graf A.H., Schielchl A., Hacker G.W., Hauser-Kronberger C., Steiner H., Arimura A., Sundler F., Standach A., Dietze O. Helospectin and pituitary adenylate cyclase activating polypeptide in the human vagina. Regul Pept. 55:1995;277-286.
22. Yada T., Sakurada M., Ihida K., Nakata M., Murata F., Arimura A., Kikuchi M. Pituitary adenylate cyclase-activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet β-cells. J Biol Chem. 269:1994;1290-1293.
23. Yada T., Sakurada M., Ishihara H., Nakata M., Yaekura K., Kikuchi M., Oka Y. PACAP as an intra-islet amplifier of glucose-induced insulin secretion. Diabetologia. 40(suppl. 1):1997;A112.
24. Rawlings S.R., Hezareh M. Pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP/vasoactive intestinal polypeptide receptors: actions on the anterior pituitary gland. Endocr Rev. 17:1996;4-29.
25. Arimura A., Shioda S. Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: neuroendocrine and endocrine interaction. Front Neuroendocrinol. 16:1995;53-88.
26. Wei Y., Mojsov S. Tissue specific expression of different human receptor types for pituitary adenylate cyclase activating polypeptide and vasoactive intestinal polypeptide: implications for their role in human physiology. J Neuroendocrinol. 8:1996;811-818.
27. Waschek J.A., Richards M.L., Bravo D.T. Differential expression of VIP/PACAP receptor genes in breast, intestinal, and pancreatic cell lines. Cancer Lett. 92:1995;143-149.
28. Usdin T.B., Bonner T.I., Mezey E. Two receptors for vasoactive intestinal polypeptide with similar specificity and complementary distributions. Endocrinology. 135:1994;2662-2680.
29. Straub S.G., Sharp G.W. A wortmannin-sensitive signal transduction pathway is involved in the stimulation of insulin release by vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide. J Biol Chem. 271:1996;1660-1668.
30. Yokota C., Kawai K., Ohashi S., Watanabe Y., Suzuki S., Yamashita K. Stimulatory effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on insulin and glucagon release from the isolated perfused rat pancreas. Acta Endocrinol. 129:1993;473-479.
31. Bertrand G., Puech R., Maissonnasse Y., Bockaert J., Loubatières-Mariani M.M. Comparative effects of PACAP and VIP on pancreatic endocrine secretions and vascular resistance in rat. Br J Pharmacol. 117:1996;764-770.
32. Kawai K., Ohse C., Watanabe Y., Suzuki S., Yamashita K., Ohashi S. Pituitary adenylate cyclase activating polypeptide stimulates insulin release from the isolated perfused rat pancreas. Life Sci. 50:1992;257-261.
33. Kitamura D., Roes J., Kuhn R., Rajewsky K. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene. Nature. 350:1991;423-426.
34. Elsås T., Uddman R., Mulder H., Sundler F. Pituitary adenylate cyclase activating polypeptide and nitric oxide are expressed in the rat ciliary ganglion. Br J Ophthalmol. 81:1997;223-227.
35. Mulder H., Uddman R., Moller K., Zhang Y.Z., Ekblad E., Alumets J., Sundler F. Pituitary adenylate cyclase activating polypeptide expression in sensory neurons. Neuroscience. 63:1994;307-312.
36. Moller K., Sundler F. Expression of pituitary adenylate cyclase activating peptide (PACAP) and PACAP type I receptors in the rat adrenal medulla. Regul Pept. 63:1996;129-139.
37. af Klinteberg K., Karisson S., Moller K., Sundler F., Ahrén B. Pituitary adenylate cyclase-activating polypeptide (PACAP) and insulin secretion: effects and mechanisms. New York Ann Sci. 805:1996;543-548.
38. Ishihara T., Shigemoto R., Mon K., Takahashi K., Nagata S. Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide. Neuron. 8:1992;811-819.
39. 2 receptor: molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide. FEBS Lett. 334:1993;3-8.
40. Mulder H., Lindh A.C., Sundler F. Islet amyloid polypeptide is expressed in the endocrine pancreas of the rat: a combined in situ hybridization and immunocytochemical study. Cell Tissue Res. 274:1993;467-474.
41. Kimura C., Ohkubo S., Ogi K., Hosoya M., Itoh Y., Onda H., Miyata A., Jiang L., Dahl R.R., Stibbs H.H., Arimura A., Fujino M. A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs. Biochem Biophys Res Commun. 166:1990;81-89.
42. Inagaki N., Yoshida H., Mizuta M., Mizuno M., Fujii Y., Gonoi T., Miyazaki J., Seino S. Cloning and functional characterization of a third pituitary adenylate cyclase-activating polypeptide receptor subtype expressed in insulin-secreting cells. Proc Natl Acad Sci USA. 91:1994;2679-2683.
43. Kashimura J., Shimosegawa T., Kikuchi Y., Koizumi M., Toyota T. The effect of PACAP38 on amylase release and cAMP production in dispersed rat pancreatic acini - a comparison with VIP. Biomed Res. 13:1992;347-351.
44. af Klinteberg K., Al-Amin A.N., Hannibal J., Sundler F., Ahrén B. Effects and localization of the neuropeptide PACAP and PACAP receptor expression in insulin-producing tissues. Diabetologia. 39(suppl. 1):1996;A71.