Evidence for a significant role of a Gs-triggered mechanism unrelated to the activation of adenylyl cyclase in the cyclic AMP-independent relaxant response of guinea-pig tracheal smooth muscle

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 368, Issue 5, 2003, Pages 437-441

  Tanaka, Yoshio ^a   Yamashita, Yoko ^a   Yamaki, Fumiko ^a   Horinouchi, Takahiro ^a   Shigenobu, Koki ^a   Koike, Katsuo ^a  

^a TOHO UNIVERSITY   (Japan)

Author keywords

Adenylyl cyclase; Airway smooth muscle; Cholera toxin (CTX); Cyclic AMP; SQ 22,536

Indexed keywords

9 (TETRAHYDRO 2 FURYL)ADENINE; ADENYLATE CYCLASE; ADENYLATE CYCLASE INHIBITOR; CHOLERA TOXIN; CYCLIC AMP; ENZYME INHIBITOR; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; ENZYME ACTIVATION; FEMALE; GUINEA PIG; MALE; NONHUMAN; SMOOTH MUSCLE RELAXATION; TISSUE LEVEL; TRACHEA MUSCLE;

ADENYLATE CYCLASE; ANIMALS; CHOLERA TOXIN; CYCLIC AMP; ENZYME ACTIVATION; FEMALE; FORSKOLIN; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GUINEA PIGS; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH; TIME FACTORS; TRACHEA;

EID: 0344676404     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-003-0809-1     Document Type: Article

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