Dissociation between β-adrenoceptor-mediated cyclic AMP accumulation and inhibition of histamine-stimulated phosphoinositide metabolism in airways smooth muscle

Biochemical Pharmacology

Volumn 53, Issue 10, 1997, Pages 1565-1568

  Chilvers, Edwin R ^a   Lynch, Barbara J ^b   Challiss, R A John ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b NONE

Author keywords

2 adrenoceptors; Airways smooth muscle; Cyclic AMP; H1 histamine receptors; Inositol phosphates; Salbutamol; Salmeterol

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; HISTAMINE; HISTAMINE H1 RECEPTOR; INOSITOL PHOSPHATE; ISOBUTYLMETHYLXANTHINE; PHOSPHODIESTERASE INHIBITOR; SALBUTAMOL; SALMETEROL; TRITIUM;

AIRWAY OBSTRUCTION; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHODILATATION; CATTLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE TONE; TRACHEA MUSCLE;

1-METHYL-3-ISOBUTYLXANTHINE; ADRENERGIC BETA-AGONISTS; ALBUTEROL; ANIMALS; BRONCHODILATOR AGENTS; CATTLE; CULTURE TECHNIQUES; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE; MUSCLE, SMOOTH; PHOSPHATIDYLINOSITOLS; PHOSPHODIESTERASE INHIBITORS; RECEPTORS, ADRENERGIC, BETA; RESPIRATORY SYSTEM;

EID: 0030738235     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00069-5     Document Type: Article

References (9)

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