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Volumn 81, Issue 1-2, 1999, Pages 89-101

In vivo functional analysis of Drosophila Gap1: Involvement of Ca2+ and IP4 regulation

Author keywords

C2 domain; Gap1; GTPase activating protein; PH domain; Phospholipase C

Indexed keywords

CALCIUM ION; GLUTAMINE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; INOSITOL 1,3,4,5 TETRAKISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE; ISOENZYME; ISOPROTEIN; PHOSPHOLIPASE C; PROTEIN TYROSINE KINASE;

EID: 0344572794     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(98)00230-5     Document Type: Article
Times cited : (9)

References (53)
  • 1
    • 0028796087 scopus 로고
    • The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination
    • Begemann G., Michon A.M., v. d. Voorn L., Wepf R., Mlodzik M. The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination. Development. 121:1995;225-235.
    • (1995) Development , vol.121 , pp. 225-235
    • Begemann, G.1    Michon, A.M.2    V. D. Voorn, L.3    Wepf, R.4    Mlodzik, M.5
  • 2
    • 0027397544 scopus 로고
    • 2+ signalling
    • 2+ signalling. Nature. 361:1993;315-325.
    • (1993) Nature , vol.361 , pp. 315-325
    • Berridge, M.J.1
  • 3
    • 0024380498 scopus 로고
    • Regulation of the complex pattern of sevenless expression in the developing Drosophila eye
    • Bowtell D.D., Kimmel B.E., Simon M.A., Rubin G.M. Regulation of the complex pattern of sevenless expression in the developing Drosophila eye. Proc. Natl. Acad. Sci. USA. 86:1989;6245-6249.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 6245-6249
    • Bowtell, D.D.1    Kimmel, B.E.2    Simon, M.A.3    Rubin, G.M.4
  • 4
    • 0024026320 scopus 로고
    • Nucleotide sequence and structure of the sevenless gene of Drosophila melanogaster
    • Bowtell D.D., Simon M.A., Rubin G.M. Nucleotide sequence and structure of the sevenless gene of Drosophila melanogaster. Genes Dev. 2:1988;620-634.
    • (1988) Genes Dev. , vol.2 , pp. 620-634
    • Bowtell, D.D.1    Simon, M.A.2    Rubin, G.M.3
  • 5
    • 0344643517 scopus 로고    scopus 로고
    • Linking the cell surface with Ras: Son of sevenless guanine nucleotide exchange factors
    • Bowtell D.D.L. Linking the cell surface with Ras: son of sevenless guanine nucleotide exchange factors. Curr. Opin. Endocrinol. Diabetes. 3:1996;388-396.
    • (1996) Curr. Opin. Endocrinol. Diabetes , vol.3 , pp. 388-396
    • Bowtell, D.D.L.1
  • 6
    • 0029883564 scopus 로고    scopus 로고
    • N-terminal sequences contained in the Src homology 2 and 3 domains of p120 GTPase-activating protein are required for full catalytic activity toward Ras
    • Bryant S.S., Mitchell A.L., Collins F., Miao W., Marshall M., Jove R. N-terminal sequences contained in the Src homology 2 and 3 domains of p120 GTPase-activating protein are required for full catalytic activity toward Ras. J. Biol. Chem. 271:1996;5195-5199.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5195-5199
    • Bryant, S.S.1    Mitchell, A.L.2    Collins, F.3    Miao, W.4    Marshall, M.5    Jove, R.6
  • 7
    • 0026643441 scopus 로고
    • Mip causes hyperinnervation of a retinotopic map in Drosophila by excessive recruitment of R7 photoreceptor cells
    • Buckles G.R., Smith Z.D., Katz F.N. mip causes hyperinnervation of a retinotopic map in Drosophila by excessive recruitment of R7 photoreceptor cells. Neuron. 8:1992;1015-1029.
    • (1992) Neuron , vol.8 , pp. 1015-1029
    • Buckles, G.R.1    Smith, Z.D.2    Katz, F.N.3
  • 8
    • 0024377179 scopus 로고
    • The emergence of order in the Drosophila pupal retina
    • Cagan R.L., Ready D.F. The emergence of order in the Drosophila pupal retina. Dev. Biol. 136:1989;346-362.
    • (1989) Dev. Biol. , vol.136 , pp. 346-362
    • Cagan, R.L.1    Ready, D.F.2
  • 10
    • 0029930117 scopus 로고    scopus 로고
    • Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK
    • Cleghon V., Gayko U., Copeland T.D., Perkins L.A., Perrimon N., Morrison D.K. Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK. Genes Dev. 10:1996;566-577.
    • (1996) Genes Dev. , vol.10 , pp. 566-577
    • Cleghon, V.1    Gayko, U.2    Copeland, T.D.3    Perkins, L.A.4    Perrimon, N.5    Morrison, D.K.6
  • 13
    • 0026320247 scopus 로고
    • Suppression of src transformation by overexpression of full-length GTPase-activating protein (GAP) or of the GAP C terminus
    • DeClue J.E., Zhang K., Redford P., Vass W.C., Lowy D.R. Suppression of src transformation by overexpression of full-length GTPase-activating protein (GAP) or of the GAP C terminus. Mol. Cell. Biol. 11:1991;2819-2825.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 2819-2825
    • Declue, J.E.1    Zhang, K.2    Redford, P.3    Vass, W.C.4    Lowy, D.R.5
  • 14
    • 0026528368 scopus 로고
    • Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis
    • DeClue J.E., Papageorge A.G., Fletcher J.A., Diehl S.R., Ratner N., Vass W.C., Lowy D.R. Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis. Cell. 69:1992;265-273.
    • (1992) Cell , vol.69 , pp. 265-273
    • Declue, J.E.1    Papageorge, A.G.2    Fletcher, J.A.3    Diehl, S.R.4    Ratner, N.5    Vass, W.C.6    Lowy, D.R.7
  • 15
    • 0027515798 scopus 로고
    • Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein
    • Ellis M.C., O'Neill E.M., Rubin G.M. Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein. Development. 119:1993;855-865.
    • (1993) Development , vol.119 , pp. 855-865
    • Ellis, M.C.1    O'Neill, E.M.2    Rubin, G.M.3
  • 16
    • 0028168521 scopus 로고
    • Drosophila phospholipase C-γ expressed predominantly in blastoderm cells at cellularization and in endodermal cells during later embryonic stages
    • Emori Y., Sugaya R., Akimaru H., Higashijima S., Shishido E., Saigo K., Homma Y. Drosophila phospholipase C-γ expressed predominantly in blastoderm cells at cellularization and in endodermal cells during later embryonic stages. J. Biol. Chem. 269:1994;19474-19479.
    • (1994) J. Biol. Chem. , vol.269 , pp. 19474-19479
    • Emori, Y.1    Sugaya, R.2    Akimaru, H.3    Higashijima, S.4    Shishido, E.5    Saigo, K.6    Homma, Y.7
  • 17
    • 0026575220 scopus 로고
    • Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation
    • Fortini M.E., Simon M.A., Rubin G.M. Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation. Nature. 355:1992;559-561.
    • (1992) Nature , vol.355 , pp. 559-561
    • Fortini, M.E.1    Simon, M.A.2    Rubin, G.M.3
  • 18
    • 0029748612 scopus 로고    scopus 로고
    • m. Determination of the inositol 1,3,4,5-tetrakisphosphate-binding domain
    • m. Determination of the inositol 1,3,4,5-tetrakisphosphate-binding domain. J. Biol. Chem. 271:1996;18838-18842.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18838-18842
    • Fukuda, M.1    Mikoshiba, K.2
  • 19
    • 0030895606 scopus 로고    scopus 로고
    • Regulation by bivalent cations of phospholipid binding to the C2A domain of synaptotagmin III
    • Fukuda M., Kojima T., Mikoshiba K. Regulation by bivalent cations of phospholipid binding to the C2A domain of synaptotagmin III. Biochem. J. 323:1997;421-425.
    • (1997) Biochem. J. , vol.323 , pp. 421-425
    • Fukuda, M.1    Kojima, T.2    Mikoshiba, K.3
  • 20
    • 0026588783 scopus 로고
    • A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase
    • Gaul U., Mardon G., Rubin G.M. A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase. Cell. 68:1992;1007-1019.
    • (1992) Cell , vol.68 , pp. 1007-1019
    • Gaul, U.1    Mardon, G.2    Rubin, G.M.3
  • 21
    • 0026711081 scopus 로고
    • Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: The C-terminal domain of GAP is not sufficient for full activity
    • Gideon P., John J., Frech M., Lautwein A., Clark R., Scheffler J.E., Wittinghofer A. Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity. Mol. Cell. Biol. 12:1992;2050-2056.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2050-2056
    • Gideon, P.1    John, J.2    Frech, M.3    Lautwein, A.4    Clark, R.5    Scheffler, J.E.6    Wittinghofer, A.7
  • 22
    • 0031455262 scopus 로고    scopus 로고
    • Different levels of Ras activity can specify distinct transcriptional and morphological consequences in early Drosophila embryos
    • Greenwood S., Struhl G. Different levels of Ras activity can specify distinct transcriptional and morphological consequences in early Drosophila embryos. Development. 124:1997;4879-4886.
    • (1997) Development , vol.124 , pp. 4879-4886
    • Greenwood, S.1    Struhl, G.2
  • 23
    • 0028141705 scopus 로고
    • Expression of baculovirus p35 prevents cell death in Drosophila
    • Hay B.A., Wolff T., Rubin G.M. Expression of baculovirus p35 prevents cell death in Drosophila. Development. 120:1994;2121-2129.
    • (1994) Development , vol.120 , pp. 2121-2129
    • Hay, B.A.1    Wolff, T.2    Rubin, G.M.3
  • 24
    • 0028947685 scopus 로고
    • The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway
    • Hou X.S., Chou T.B., Melnick M.B., Perrimon N. The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway. Cell. 81:1995;63-71.
    • (1995) Cell , vol.81 , pp. 63-71
    • Hou, X.S.1    Chou, T.B.2    Melnick, M.B.3    Perrimon, N.4
  • 25
    • 0029826308 scopus 로고    scopus 로고
    • Undifferentiated cells in the developing Drosophila eye influence facet assembly and require the Fat facets ubiquitin-specific protease
    • Huang Y., Fischer-Vize J. Undifferentiated cells in the developing Drosophila eye influence facet assembly and require the Fat facets ubiquitin-specific protease. Development. 122:1996;3207-3216.
    • (1996) Development , vol.122 , pp. 3207-3216
    • Huang, Y.1    Fischer-Vize, J.2
  • 26
    • 0039710379 scopus 로고    scopus 로고
    • Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: Molecular explanations for X-linked agammaglobulinaemia
    • Hyvönen M., Saraste M. Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia. EMBO J. 16:1997;3396-3404.
    • (1997) EMBO J. , vol.16 , pp. 3396-3404
    • Hyvönen, M.1    Saraste, M.2
  • 28
    • 85033005344 scopus 로고
    • Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and in grasshopper embryos
    • Jan L.Y., Jan Y.N. Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and in grasshopper embryos. Proc. Natl. Acad. Sci. USA. 89:1982;1919-1923.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1919-1923
    • Jan, L.Y.1    Jan, Y.N.2
  • 29
    • 0025252220 scopus 로고
    • PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex
    • Kaplan D.R., Morrison D.K., Wong G., McCormick F., Williams L.T. PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex. Cell. 61:1990;125-133.
    • (1990) Cell , vol.61 , pp. 125-133
    • Kaplan, D.R.1    Morrison, D.K.2    Wong, G.3    McCormick, F.4    Williams, L.T.5
  • 30
    • 0021473294 scopus 로고
    • Analysis of P transposable element functions in Drosophila
    • Karess R.E., Rubin G.M. Analysis of P transposable element functions in Drosophila. Cell. 38:1984;135-146.
    • (1984) Cell , vol.38 , pp. 135-146
    • Karess, R.E.1    Rubin, G.M.2
  • 32
    • 0025274965 scopus 로고
    • Binding of GAP to activated PDGF receptors
    • Kazlauskas A., Ellis C., Pawson T., Cooper J.A. Binding of GAP to activated PDGF receptors. Science. 247:1990;1578-1581.
    • (1990) Science , vol.247 , pp. 1578-1581
    • Kazlauskas, A.1    Ellis, C.2    Pawson, T.3    Cooper, J.A.4
  • 33
    • 0025276935 scopus 로고
    • The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype
    • Kimmel B.E., Heberlein U., Rubin G.M. The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype. Genes Dev. 4:1990;712-727.
    • (1990) Genes Dev. , vol.4 , pp. 712-727
    • Kimmel, B.E.1    Heberlein, U.2    Rubin, G.M.3
  • 34
    • 0028999815 scopus 로고
    • Cell fate control in the Drosophila retina by the orphan receptor seven-up: Its role in the decisions mediated by the ras signaling pathway
    • Kramer S., West S.R., Hiromi Y. Cell fate control in the Drosophila retina by the orphan receptor seven-up: its role in the decisions mediated by the ras signaling pathway. Development. 121:1995;1361-1372.
    • (1995) Development , vol.121 , pp. 1361-1372
    • Kramer, S.1    West, S.R.2    Hiromi, Y.3
  • 35
    • 0026723089 scopus 로고
    • Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein
    • Lai Z.C., Rubin G.M. Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein. Cell. 70:1992;609-620.
    • (1992) Cell , vol.70 , pp. 609-620
    • Lai, Z.C.1    Rubin, G.M.2
  • 38
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall C.J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell. 80:1995;179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 42
    • 0028971813 scopus 로고
    • Phosphoinositide-specific phospholipase C and mitogenic signaling
    • Noh D.Y., Shin S.H., Rhee S.G. Phosphoinositide-specific phospholipase C and mitogenic signaling. Biochim. Biophys. Acta. 1242:1995;99-113.
    • (1995) Biochim. Biophys. Acta , vol.1242 , pp. 99-113
    • Noh, D.Y.1    Shin, S.H.2    Rhee, S.G.3
  • 43
    • 0027261514 scopus 로고
    • The torso receptor protein-tyrosine kinase signaling pathway: An endless story
    • Perrimon N. The torso receptor protein-tyrosine kinase signaling pathway: an endless story. Cell. 74:1993;219-222.
    • (1993) Cell , vol.74 , pp. 219-222
    • Perrimon, N.1
  • 44
    • 0026625667 scopus 로고
    • Neuronal development in the Drosophila retina: The sextra gene defines an inhibitory component in the developmental pathway of R7 photoreceptor cells
    • Rogge R., Cagan R., Majumdar A., Dulaney T., Banerjee U. Neuronal development in the Drosophila retina: the sextra gene defines an inhibitory component in the developmental pathway of R7 photoreceptor cells. Proc. Natl. Acad. Sci. USA. 89:1992;5271-5275.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5271-5275
    • Rogge, R.1    Cagan, R.2    Majumdar, A.3    Dulaney, T.4    Banerjee, U.5
  • 45
    • 0029861146 scopus 로고    scopus 로고
    • A modular misexpression screen in Drosophila detecting tissue-specific phenotypes
    • Rørth P. A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. Proc. Natl. Acad. Sci. USA. 93:1996;12418-12422.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12418-12422
    • Rørth, P.1
  • 47
    • 0023057627 scopus 로고
    • Alternative 5′ exons and tissue-specific expression of the Drosophila EGF receptor homolog transcripts
    • Schejter E.D., Segal D., Glazer L., Shilo B.Z. Alternative 5′ exons and tissue-specific expression of the Drosophila EGF receptor homolog transcripts. Cell. 46:1986;1091-1101.
    • (1986) Cell , vol.46 , pp. 1091-1101
    • Schejter, E.D.1    Segal, D.2    Glazer, L.3    Shilo, B.Z.4
  • 49
    • 0032415833 scopus 로고    scopus 로고
    • Small wing encodes a phospholipase C-γ that acts as a negative regulator of R7 development in Drosophila
    • Thackeray J.R., Gaines P.C.W., Ebert P., Carlson J.R. small wing encodes a phospholipase C-γ that acts as a negative regulator of R7 development in Drosophila. Development. 125:1998;5033-5042.
    • (1998) Development , vol.125 , pp. 5033-5042
    • Thackeray, J.R.1    Gaines, P.C.W.2    Ebert, P.3    Carlson, J.R.4
  • 50
    • 0023649258 scopus 로고
    • Localization of the Sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila
    • Tomlinson A., Bowtell D.D.L., Hafen E., Rubin G.M. Localization of the Sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila. Cell. 51:1987;143-150.
    • (1987) Cell , vol.51 , pp. 143-150
    • Tomlinson, A.1    Bowtell, D.D.L.2    Hafen, E.3    Rubin, G.M.4
  • 51
    • 0030899808 scopus 로고    scopus 로고
    • Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap
    • van der Geer P., Henkemeyer M., Jacks T., Pawson T. Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap. Mol. Cell. Biol. 17:1997;1840-1847.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1840-1847
    • Van Der Geer, P.1    Henkemeyer, M.2    Jacks, T.3    Pawson, T.4
  • 52
    • 0027941128 scopus 로고
    • Tec homology (TH) adjacent to the PH domain
    • Vihinen M., Nilsson L., Smith C.I. Tec homology (TH) adjacent to the PH domain. FEBS Lett. 350:1994;263-265.
    • (1994) FEBS Lett. , vol.350 , pp. 263-265
    • Vihinen, M.1    Nilsson, L.2    Smith, C.I.3
  • 53
    • 0025244911 scopus 로고
    • The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae
    • Xu G.F., Lin B., Tanaka K., Dunn D., Wood D., Gesteland R., White R., Weiss R., Tamanoi F. The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae. Cell. 63:1990;835-841.
    • (1990) Cell , vol.63 , pp. 835-841
    • Xu, G.F.1    Lin, B.2    Tanaka, K.3    Dunn, D.4    Wood, D.5    Gesteland, R.6    White, R.7    Weiss, R.8    Tamanoi, F.9


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