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Volumn 15, Issue 6, 2003, Pages 684-690

Cytokinesis: Progress on all fronts

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; KINESIN; METHENAMINE; MICROTUBULE ASSOCIATED PROTEIN; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RNA;

EID: 0344413429     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ceb.2003.10.003     Document Type: Review
Times cited : (38)

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    • The mammalian passenger protein TD-60 is an RCC1 family member with an essential role in prometaphase to metaphase progression
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    • Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis
    • This paper reports that Plk1 phosphorylates the kinesin-like protein MKLP2 thereby generating a docking site for Plk1 in the central spindle
    • Neef R., Preisinger C., Sutcliffe J., Kopajtich R., Nigg E.A., Mayer T.U., Barr F.A. Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J. Cell Biol. 162:2003;863-875 This paper reports that Plk1 phosphorylates the kinesin-like protein MKLP2 thereby generating a docking site for Plk1 in the central spindle.
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    • Microtubules are the only structural constituent of the spindle apparatus required for induction of cell cleavage
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    • Alsop G.B., Zhang D. Microtubules are the only structural constituent of the spindle apparatus required for induction of cell cleavage. J. Cell Biol. 162:2003;383-390 This paper provides further evidence that microtubule bundles are sufficient to induce cleavage furrows; asters and chromosome can be simultaneously removed without preventing furrow formation.
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    • The mouse formin mDia1 is a potent actin nucleation factor regulated by autoinhibition
    • The most recent demonstration of actin nucleation by formins also reports that the amino terminus of mDia inhibits the nucleation activity of the carboxyl terminus and that RhoA regulates this inhibition
    • Li F., Higgs H.N. The mouse formin mDia1 is a potent actin nucleation factor regulated by autoinhibition. Curr. Biol. 13:2003;1335-1340 The most recent demonstration of actin nucleation by formins also reports that the amino terminus of mDia inhibits the nucleation activity of the carboxyl terminus and that RhoA regulates this inhibition.
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    • Li, F.1    Higgs, H.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.