메뉴 건너뛰기




Volumn 46, Issue 9, 1997, Pages 1400-1405

Role of the glucagon receptor COOH-terminal domain in glucagon-mediated signaling and receptor internalization

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLIC AMP; GLUCAGON RECEPTOR;

EID: 0030840615     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.9.1400     Document Type: Article
Times cited : (28)

References (33)
  • 1
    • 0017905093 scopus 로고
    • Insulin, glucagon, and somatostatin secretion in the regulation of metabolism
    • Unger RH, Dobbs RE, Orci L: Insulin, glucagon, and somatostatin secretion in the regulation of metabolism. Annu Rev Physiol 40:307-343, 1978
    • (1978) Annu Rev Physiol , vol.40 , pp. 307-343
    • Unger, R.H.1    Dobbs, R.E.2    Orci, L.3
  • 3
    • 0004188835 scopus 로고
    • Philadelphia, Saunders
    • DeGroot LJ (Ed.): Endocrinology. Philadelphia, Saunders, 1989, p. 1333-1345
    • (1989) Endocrinology , pp. 1333-1345
    • DeGroot, L.J.1
  • 4
    • 0025372837 scopus 로고
    • The genes of hepatic glucose metabolism
    • Granner D, Pilkis S: The genes of hepatic glucose metabolism. J Biol Chem 265:10173-10176, 1990
    • (1990) J Biol Chem , vol.265 , pp. 10173-10176
    • Granner, D.1    Pilkis, S.2
  • 5
    • 0023041534 scopus 로고
    • Activation of two signal-transduction systems in hepatocytes by glucagon
    • Wakelam MJ, Murphy GJ, Hruby VJ, Houslay MD: Activation of two signal-transduction systems in hepatocytes by glucagon. Nature 323:68-71, 1986
    • (1986) Nature , vol.323 , pp. 68-71
    • Wakelam, M.J.1    Murphy, G.J.2    Hruby, V.J.3    Houslay, M.D.4
  • 6
    • 0029054042 scopus 로고
    • Glucagon receptors: From genetic structure and expression to effector coupling and biological responses
    • Christophe J: Glucagon receptors: from genetic structure and expression to effector coupling and biological responses. Biochim Biophys Acta 1241:45-57, 1995
    • (1995) Biochim Biophys Acta , vol.1241 , pp. 45-57
    • Christophe, J.1
  • 11
    • 0028987130 scopus 로고
    • Glucagon/glucagon-like peptide I receptor chimeras reveal domains that determine specificity of glucagon binding
    • Buggy JJ, Livingston JN, Rabin DU, Yoo-Warren H: Glucagon/glucagon-like peptide I receptor chimeras reveal domains that determine specificity of glucagon binding. J Biol Chem 270:7474-7478, 1995
    • (1995) J Biol Chem , vol.270 , pp. 7474-7478
    • Buggy, J.J.1    Livingston, J.N.2    Rabin, D.U.3    Yoo-Warren, H.4
  • 12
    • 0028046153 scopus 로고
    • Synthesis and expression of a gene for the rat glucagon receptor: Replacement of an aspartic acid in the extracellular domain prevents glucagon binding
    • Carruthers CJ, Unson CG, Kim HN, Sakmar TP: Synthesis and expression of a gene for the rat glucagon receptor: replacement of an aspartic acid in the extracellular domain prevents glucagon binding. J Biol Chem 269:29321-29328, 1994
    • (1994) J Biol Chem , vol.269 , pp. 29321-29328
    • Carruthers, C.J.1    Unson, C.G.2    Kim, H.N.3    Sakmar, T.P.4
  • 13
    • 0028889191 scopus 로고
    • Stable expression of a truncated AT1a receptor in CHO-K1 cells: The carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization
    • Thomas WG, Thekkumkara TJ, Motel TJ, Baker KM: Stable expression of a truncated AT1A receptor in CHO-K1 cells: the carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization. J Biol Chem 270:207-213, 1995
    • (1995) J Biol Chem , vol.270 , pp. 207-213
    • Thomas, W.G.1    Thekkumkara, T.J.2    Motel, T.J.3    Baker, K.M.4
  • 15
    • 0028840145 scopus 로고
    • The cytoplasmic tail of the G-protein-coupled receptor for parathyroid hormone and parathyroid hormone-related protein contains positive and negative signals for endocytosis
    • Huang Z, Chen Y, Nissenson RA: The cytoplasmic tail of the G-protein-coupled receptor for parathyroid hormone and parathyroid hormone-related protein contains positive and negative signals for endocytosis. J Biol Chem 270:151-156, 1995
    • (1995) J Biol Chem , vol.270 , pp. 151-156
    • Huang, Z.1    Chen, Y.2    Nissenson, R.A.3
  • 16
    • 0028788229 scopus 로고
    • Characterization of deletion and truncation mutants of the rat glucagon receptor: Seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding
    • Unson CG, Cypess AM, Kim HN, Goldsmith PK, Carruthers CJ, Merrifield RB, Sakmar TP: Characterization of deletion and truncation mutants of the rat glucagon receptor: seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding. J Biol Chem 270:27720-27727, 1995
    • (1995) J Biol Chem , vol.270 , pp. 27720-27727
    • Unson, C.G.1    Cypess, A.M.2    Kim, H.N.3    Goldsmith, P.K.4    Carruthers, C.J.5    Merrifield, R.B.6    Sakmar, T.P.7
  • 17
    • 0027936264 scopus 로고
    • Protein kinase A induces phosphorylation of the human 5-HT1A receptor and augments its desensitization by protein kinase C in CHO-K1 cells
    • Raymond JR, Olsen CL: Protein kinase A induces phosphorylation of the human 5-HT1A receptor and augments its desensitization by protein kinase C in CHO-K1 cells. Biochemistry 33:11264-11269, 1994
    • (1994) Biochemistry , vol.33 , pp. 11264-11269
    • Raymond, J.R.1    Olsen, C.L.2
  • 18
    • 0025223081 scopus 로고
    • Turning off the signal: Desensitization of beta-adrenergic receptor function
    • Hausdorff WP, Caron MG, Lefkowitz RJ: Turning off the signal: desensitization of beta-adrenergic receptor function. FASEB J 4:2881-2889, 1990
    • (1990) FASEB J , vol.4 , pp. 2881-2889
    • Hausdorff, W.P.1    Caron, M.G.2    Lefkowitz, R.J.3
  • 19
    • 0029903146 scopus 로고    scopus 로고
    • Glucagon induces a rapid and sustained phosphorylation of the human glucagon receptor in Chinese hamster ovary cells
    • Heurich RO, Buggy JJ, Vandenberg MT, Rossomando AJ: Glucagon induces a rapid and sustained phosphorylation of the human glucagon receptor in Chinese hamster ovary cells. Biochem Biophys Res Commun 220:905-910, 1996
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 905-910
    • Heurich, R.O.1    Buggy, J.J.2    Vandenberg, M.T.3    Rossomando, A.J.4
  • 20
    • 0005261734 scopus 로고
    • Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro
    • Ray LB, Sturgill TW: Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro. Proc Natl Acad Sci USA 84:1502-1506, 1987
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1502-1506
    • Ray, L.B.1    Sturgill, T.W.2
  • 21
    • 0025905209 scopus 로고
    • Very early detection of changes associated with cellular activation using a modified flow cytometer
    • Kelley KA: Very early detection of changes associated with cellular activation using a modified flow cytometer. Cytometry 12:464-468, 1991
    • (1991) Cytometry , vol.12 , pp. 464-468
    • Kelley, K.A.1
  • 22
    • 0022976869 scopus 로고
    • Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon: Modulation by cAMP and phorbol myristate acetate
    • Blackmore PF, Exton JH: Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon: modulation by cAMP and phorbol myristate acetate. J Biol Chem 261:11056-11063, 1986
    • (1986) J Biol Chem , vol.261 , pp. 11056-11063
    • Blackmore, P.F.1    Exton, J.H.2
  • 23
    • 0021895138 scopus 로고
    • 2+ indicators with greatly improved fluorescence properties
    • 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450, 1985
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 24
    • 0022472020 scopus 로고
    • Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3: Simultaneous use of INDO-1 and immunofluorescence with flow cytometry
    • Rabinovitch PS, June CH, Grossmann A, Ledbetter JA: Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3: simultaneous use of INDO-1 and immunofluorescence with flow cytometry. J Immunol 137:952-961, 1986
    • (1986) J Immunol , vol.137 , pp. 952-961
    • Rabinovitch, P.S.1    June, C.H.2    Grossmann, A.3    Ledbetter, J.A.4
  • 25
    • 0025940262 scopus 로고
    • Degradation of glucagon in isolated liver endosomes: ATP-dependence and partial characterization of degradation products
    • Authier F, Desbuquois B: Degradation of glucagon in isolated liver endosomes: ATP-dependence and partial characterization of degradation products. Biochem J 280:211-218, 1991
    • (1991) Biochem J , vol.280 , pp. 211-218
    • Authier, F.1    Desbuquois, B.2
  • 26
    • 0026725249 scopus 로고
    • Ligand-mediated internalization of glucagon receptors in intact rat liver
    • Authier F, Desbuquois B, De Galle B: Ligand-mediated internalization of glucagon receptors in intact rat liver. Endocrinology 131:447-457, 1992
    • (1992) Endocrinology , vol.131 , pp. 447-457
    • Authier, F.1    Desbuquois, B.2    De Galle, B.3
  • 27
    • 0025661999 scopus 로고
    • Fate of injected glucagon taken up by rat liver in vivo: Degradation of internalized ligand in the endosomal compartment
    • Authier F, Janicot M, Lederer F, Desbuquois B: Fate of injected glucagon taken up by rat liver in vivo: degradation of internalized ligand in the endosomal compartment. Biochem J 272:703-712, 1990
    • (1990) Biochem J , vol.272 , pp. 703-712
    • Authier, F.1    Janicot, M.2    Lederer, F.3    Desbuquois, B.4
  • 28
    • 0028998783 scopus 로고
    • Proteolysis of glucagon within hepatic endosomes by membrane-associated cathepsins B and D
    • Authier F, Mort JS, Bell AW, Posner BI, Bergeron JJ: Proteolysis of glucagon within hepatic endosomes by membrane-associated cathepsins B and D. J Biol Chem 270:15798-15807, 1995
    • (1995) J Biol Chem , vol.270 , pp. 15798-15807
    • Authier, F.1    Mort, J.S.2    Bell, A.W.3    Posner, B.I.4    Bergeron, J.J.5
  • 29
    • 0023897940 scopus 로고
    • Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization
    • Bouvier M, Hausdorff WP, De Blasi A, O'Dowd BF, Kobilka BK, Caron MG, Lefkowitz RJ: Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization. Nature 333:370-373, 1988
    • (1988) Nature , vol.333 , pp. 370-373
    • Bouvier, M.1    Hausdorff, W.P.2    De Blasi, A.3    O'Dowd, B.F.4    Kobilka, B.K.5    Caron, M.G.6    Lefkowitz, R.J.7
  • 30
    • 0029810617 scopus 로고    scopus 로고
    • Heterologous desensitization of the glucagon-like peptide-1 receptor by phorbol esters requires phosphorylation of the cytoplasmic tail at four different sites
    • Widmann C, Dolci W, Thorens B: Heterologous desensitization of the glucagon-like peptide-1 receptor by phorbol esters requires phosphorylation of the cytoplasmic tail at four different sites. J Biol Chem 271:19957-19963, 1996
    • (1996) J Biol Chem , vol.271 , pp. 19957-19963
    • Widmann, C.1    Dolci, W.2    Thorens, B.3
  • 32
    • 0030593035 scopus 로고    scopus 로고
    • Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
    • Ferguson SS, Downey WE, Colapietro AM, Barak LS, Menard L, Caron MG: Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 271:363-366, 1996
    • (1996) Science , vol.271 , pp. 363-366
    • Ferguson, S.S.1    Downey, W.E.2    Colapietro, A.M.3    Barak, L.S.4    Menard, L.5    Caron, M.G.6
  • 33
    • 0028949133 scopus 로고
    • Adenylyl cyclases and the interaction between calcium and cAMP signalling
    • Cooper DM, Mons N, Karpen JW: Adenylyl cyclases and the interaction between calcium and cAMP signalling. Nature 374:421-124, 1995
    • (1995) Nature , vol.374 , pp. 421-1124
    • Cooper, D.M.1    Mons, N.2    Karpen, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.