Peroxynitrite, the breakdown product of nitric oxide, is beneficial in blood cardioplegia but injurious in crystalloid cardioplegia

Circulation

Volumn 100, Issue 19 SUPPL., 1999, Pages

  Ronson, Russell S ^a   Thourani, Vinod H ^a   Ma, Xin Liang ^a   Katzmark, Sara L ^a   Han, David ^a   Zhao, Zhi Qing ^a   Nakamura, Masanori ^a   Guyton, Robert A ^a   Vinten Johansen, Jakob ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Carlyle Fraser Heart Center   (United States)

Author keywords

Cardioplegia; Cardiopulmonary bypass; Nitric oxide; Peroxynitrite; Superoxide

Indexed keywords

NITRIC OXIDE; PEROXYNITRITE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOPLEGIA; CARDIOPULMONARY BYPASS; CRYSTALLOID; DOG; FEMALE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE BIOPSY; HEART MUSCLE REPERFUSION; HEMODYNAMIC PARAMETERS; MALE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CARDIOPULMONARY BYPASS; DOGS; HEART ARREST, INDUCED; MYOCARDIAL REPERFUSION INJURY; NITRATES; NITRIC OXIDE; OXIDANTS;

EID: 0344339187     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Lefer DJ, Nakanishi K, Johnston WE, Feelisch M, Vinten-Johansen J. Anti-neutrophil and myocardial protecting actions of SPM-5185, a novel nitric oxide (NO) donor, following acute myocardial ischemia and reperfusion in dogs. Biol Nitric Oxide. 1992;188-190.
2. Sato H, Zhao Z-Q, McGee DS, Williams MW, Hammon JW Jr, Vinten-Johansen J. Supplemental L-arginine during cardioplegic arrest and reperfusion avoids regional postischemic injury. J Thorac Cardiovasc Surg. 1995;110:302-314.
3. Beresewicz A, Karwatowska-Prokopczuk E, Lewartowski B, Cedro-Ceremuzynska K. Stunning: a protective role of nitric oxide in isolated ischaemic reperfused rat heart. Cardiovasc Res. 1995;30:1001-1008.
4. Moncada S, Higgs EA. Endogenous nitric oxide: physiology, pathology and clinical relevance. J Clin Invest. 1991;21:361-374.
5. Pabla R, Buda AJ, Flynn DM, Blesse SA, Shin AM, Curtis MJ, Lefer DJ. Nitric oxide attenuates neutrophil-mediated myocardial contractile dysfunction after ischemia and reperfusion. Circ Res. 1996;78:65-72.
6. Ma X-L, Lopez BL, Liu G-L, Christopher TA, Ischiropoulos H. Peroxynitrite aggravates myocardial reperfusion injury in the isolated perfused rat heart. Cardiovasc Res. 1997;36:195-204.
7. Lopez BL, Liu G-L, Christopher TA, Ma X-L. Peroxynitrite, the product of nitric oxide and superoxide, causes myocardial injury in the isolated perfused rat heart. Coron Artery Dis. 1997;8:149-153.
8. Beckman JS. Oxidative damage and tyrosine nitration from peroxynitrite. Chem Res Toxicol. 1996;9:836-844.
9. Xia Y, Dawson VL, Dawson TM, Snyder SH, Zweier JL. Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. Proc Natl Acad Sci U S A. 1996;93:6770-6774.
10. Lopez BL, Christopher TA, Ma X-L. The effects of peroxynitrite on the myocardium during ischemia-reperfusion are dependent upon the biological environment. Endothelium. 1995;3:76. Abstract.
11. Nakanishi K, Zhao Z-Q, Vinten-Johansen J, Lewis JC, McGee DS, Hammon JWJ. Coronary artery endothelial dysfunction after ischemia, blood cardioplegia, and reperfusion. Ann Thorac Surg. 1994;58:191-199.
12. Sydzyik RT, Stammers AH, Zavadil DP, Deptula JJ, Christensen KA. Evaluation of a new generation cardioplegia administration system. J Extra-Corporeal Tech. 1997;29:145.
13. Tanaka S, Choe N, Hemenway DR, Zhu S, Mathalon S, Kagan E. Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the rat. J Clin Invest. 1998;102: 445-454.
14. Kono A, Maughan WL, Sunagawa K, Hamilton K, Sagawa K, Weisfeldt ML. The use of left ventricular end-ejection pressure and peak pressure in the estimation of the end-systolic pressure-volume relationship. Circulation. 1984;70:1057-1065.
15. Mullane KM, Kraemer R, Smith B. Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J Pharmacol Methods. 1985;14:157-167.
16. Yasmin W, Strynadka KD, Schulz R. Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts. Cardiovasc Res. 1997;33:422-432.
17. Wu M, Pritchard KA Jr, Kaminski PM, Fayngersh RP, Hintze TH, Wolin MS. Involvement of nitric oxide and nitrosothiols in relaxation of pulmonary arteries to peroxynitrite. Am J Physiol. 1994;266: H2108-H2113.
18. Davidson CA, Kaminski PM, Wolin MS. NO elicits prolonged relaxation of bovine pulmonary arteries via endogenous peroxynitrite generation. Am J Physiol. 1997;273:L437-L444.
19. Mayer B, Schrammel A, Klatt P, Koesling D, Schmidt K. Peroxynitrite-induced accumulation of cyclic GMP in endothelial cells and stimulation of purified soluble guanylyl cyclase: dependence on glutathione and possible role of S-nitrosation. J Biol Chem. 1995;270:17355-17360.
20. Wandschneider W, Winter S, Thalmann M, Howanietz N, Deutsch M. Crystalloid versus blood cardioplegia in coronary by-pass surgery: a prospective, randomized, controlled study in 100 consecutive adults. J Cardiovasc Surg. 1994;35:85-89.
21. Vinten-Johansen J, Edgerton TA, Hansen KJ, Carroll P, Mills SA, Cordell AR. Surgical revascularization of acute (1 hour) coronary occlusion: blood versus crystalloid cardioplegia. Ann Thorac Surg. 1986;42: 247-254.
22. Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys. 1991;288:481-487.
23. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci U S A. 1990;87:1620-1624.
24. Kelm M, Schrader J. Control of coronary vascular tone by nitric oxide. Circ Res. 1990;66:1561-1575.
25. Lefer DJ, Nakanishi K, Vinten-Johansen J. Endothelial and myocardial cell protection by a cysteine-containing nitric oxide donor after myocardial ischemia and reperfusion. J Cardiovasc Pharmacol. 1993;22: S34-S43.
26. Ridger VC, Greenacre SAB, Handy RLC, Halliwell B, Moore PK, Whiteman M, Brain SD. Effect of peroxynitrite on plasma extravasation, microvascular blood flow and nociception in the rat. Br J Pharmacol. 1997;122:1083-1088.
27. Davidson CA, Kaminski PM, Wu M, Wolin MS. Nitrogen dioxide causes pulmonary arterial relaxation via thiol nitrosation and NO formation. Am J Physiol. 1996;H1038-H1043.
28. Lefer DJ, Scalia R, Campbell B, Nossuli TO, Hayward R, Salamon M, Grayson J, Lefer AM. Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats. J Clin Invest. 1997;99:684-691.
29. Nossuli TO, Hayward R, Jensen D, Scalia R, Lefer AM. Mechanisms of cardioprotection by peroxynitrite in myocardial ischemia and reperfusion injury. Am J Physiol. 1998:275:H509-H519.
30. Engelman DT, Watanabe M, Maulik N, Engelman RM, Rousou JA, Flack JE III, Deaton DW, Das DK. Critical timing of nitric oxide supplementation in cardioplegic arrest and reperfusion. Circulation. 1996;94(suppl II):II-407-II-411.