Molecular cloning of testican-2: Defining a novel calcium-binding proteoglycan family expressed in brain

Journal of Neurochemistry

Volumn 73, Issue 1, 1999, Pages 12-20

  Vannahme, Christian ^a   Schübel, Sabine ^a   Herud, Marcus ^a   Gösling, Silke ^a   Hülsmann, Hanni ^a   Paulsson, Mats ^a   Hartmann, Ursula ^a   Maurer, Patrik ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Calcium; Central nervous system; Follistatin; Modular protein; Proteoglycan; Testican

Indexed keywords

BRAIN PROTEIN; CALCIUM BINDING PROTEIN; FOLLISTATIN; MESSENGER RNA; TESTICAN 2; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM TRANSPORT; CONFORMATIONAL TRANSITION; FETUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEOGLYCAN SYNTHESIS; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BRAIN CHEMISTRY; CALCIUM; CLONING, MOLECULAR; DNA, COMPLEMENTARY; FETUS; HUMANS; IN SITU HYBRIDIZATION; LUNG; MALE; MICE; MOLECULAR SEQUENCE DATA; PROTEOGLYCANS; RNA, MESSENGER; TESTICULAR HORMONES; TESTIS; TISSUE DISTRIBUTION;

EID: 0344326341     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0730012.x     Document Type: Article

References (50)

1. Alliel P. M., Perin J. P., Jolles P., and Bonnet F. J. (1993) Testican, a multidomain testicular proteoglycan resembling modulators of cell social behavior. Eur. J. Biochem. 214, 347-350.
2. Antanitus D. S. (1998) A theory of cortical neuron-astrocyte interaction. Neuroscience 4, 154-159.
3. Boguski M. S. (1995) The turning point in genome research. Trends Biochem. Sci. 20, 295-296.
4. Bonnet F., Perin J. P., Maillet P., Jolles P., and Alliel P. M. (1992) Characterization of a human seminal plasma glycosaminoglycan-bearing polypeptide. Biochem. J. 288, 565-569.
5. Bonnet F., Perin J. P., Charbonnier F., Camuzat A., Roussel G., Nussbaum J. L., and Alliel P. M. (1996) Structure and cellular distribution of mouse brain testican. Association with the postsynaptic area of hippocampus pyramidal cells. J. Biol. Chem. 271, 4373-4380.
6. Casado F. J., Pouponnot C., Jeanny J. C., Lecoq O., Calothy G., and Pierani A. (1996) QR1, a retina-specific gene, encodes an extracellular matrix protein exclusively expressed during neural retina differentiation. Mech. Dev. 54, 237-250.
7. Chaib H., Place C., Salem N., Dode C., Chardenoux S., Weissenbach J., el Zir E., Loiselet J., and Petit C. (1996) Mapping of DFNB12, a gene for a non-syndromal autosomal recessive deafness, to chromosome 10q21-22. Hum. Mol. Genet. 5, 1061-1064.
8. Charbonnier F., Perin J. P., Mattei M. G., Camuzat A., Bonnet F., Gressin L., and Alliel P. M. (1998) Genomic organization of the human SPOCK gene and its chromosomal localization to 5q31. Genomics 48, 377-380.
9. Chomczynski P., and Sacchi N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
10. Cohen N. A., Kaufmann W. E., Worley P. F., and Rupp F. (1997) Expression of agrin in the developing and adult rat brain. Neuroscience 76, 581-596.
11. Darland D. C., Link B. A., and Nishi R. (1995) Activin A and follistatin expression in developing targets of ciliary ganglion neurons suggests a role in regulating neurotransmitter phenotype. Neuron 15, 857-866.
12. Drake S. K., Zimmer M. A., Kundrot C., and Falke J. F. (1997) Molecular tuning of an EF-hand-like calcium binding loop. Contributions of the coordinating side chain at loop position 3. J. Gen. Physiol. 110, 173-184.
13. Eib D. W., and Martens G. J. (1996) A novel transmembrane protein with epidermal growth factor and follistatin domains expressed in the hypothalamo-hypophysial axis of Xenopus laevis. J. Neurochem. 67, 1047-1055.
14. Gautam M., Noakes P. G., Moscoso L., Rupp F., Scheller R. H., Merlie J. P., and Sanes J. (1996) Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Cell 85, 525-535.
15. Grumet M., Friedlander D. R., and Sakurai T. (1996) Functions of brain chondroitin sulfate proteoglycans during developments: interactions with adhesion molecules. Perspect. Dev. Neurobiol. 3, 319-330.
16. Hemmati-Brivanlou A. and Melton D. A. (1994) Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell 77, 273-281.
17. Hemmati-Brivanlou A., Kelly O. G., and Melton D. A. (1994) Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-295.
18. 2+-binding module in BM-40. Nat. Struct. Biol. 3, 67-73.
19. Hohenester E., Maurer P., and Timpl R. (1997) Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40. EMBO J. 16, 3778-3786.
20. Iemura S. I., Yamamoto T. S., Takagi C., Uchiyama H., Natsume T., Shimasaki S., Sugino H., and Ueno N. (1998) Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo. Proc. Natl. Acad. Sci. USA 95, 9337-9342.
21. Iozzo R. V. (1997) The family of the small leucine-rich proteoglycans: key regulators of matrix assembly and cellular growth. Crit. Rev. Biochem. Mol. Biol. 32, 141-174.
22. Iozzo R. V. and Murdoch A. D. (1996) Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function. FASEB J, 10, 598-614.
23. Jefferys J. G. R. (1995) Nonsynaptic modulation of neuronal activity in the brain: electric currents and extracellular ions. Physiol. Rev. 75, 689-723.
24. Kohfeldt E., Maurer P., Vannahme C., and Timpl R. (1997) Properties of the extracellular calcium binding module of the proteoglycan testican. FEBS Lett. 414, 557-561.
25. Kozak M. (1996) Interpreting cDNA sequences: some insights from studies on translation. Mamm. Genome 7, 563-574.
26. Lander A. D. (1993) Proteoglycans in the nervous system. Curr. Opin. Neurobiol. 3, 716-723.
27. Lane T. F. and Sage E. H. (1994) The biology of SPARC, a protein that modulates cell-matrix interactions. FASEB J. 8, 163-173.
28. Lankat-Buttgereit B., Mann K., Deutzmann R., Timpl R., and Krieg T. (1988) Cloning and complete amino acid sequence of human and murine basement membrane protein BM-40 (SPARC, osteonectin). FEBS Lett. 236, 352-356.
29. Margolis R. K. and Margolis R. U. (1993) Nervous tissue proteoglycans. Experientia 49, 429-446.
30. Margolis R. U. and Margolis R. K. (1997) Chondroitin sulfate proteoglycans as mediators of axon growth and path finding. Cell Tissue Res. 290, 343-348.
31. Mather J. P., Moore A., and Li R. H. (1997) Activins, inhibins, and follistatins: further thoughts on a growing family of regulators. Proc. Soc. Exp. Biol. Med. 215, 209-222.
32. Maurer P., Hohenadl C., Hohenester E., Göhring W., Timpl R., and Engel J. (1995) The C-terminal portion of BM-40 (SPARC/osteonectin) is an autonomously folding and crystallisable domain that binds calcium and collagen IV. J. Mol. Biol. 253, 347-357.
33. Maurer P., Hohenester E., and Engel J. (1996) Extracellular calcium-binding proteins. Curr. Opin. Cell Biol. 8, 609-617,
34. McKinnon P. J. and Margolskee R. F. (1996) SC1: a marker for astrocytes in the adult rodent brain is upregulated during reactive astrocytosis. Brain Res. 709, 27-36.
35. Mendis D. B., Shahin S., Gurd J. W., and Brown I. R. (1994) Developmental expression in the rat cerebellum of SC1, a putative brain extracellular matrix glycoprotein related to SPARC. Brain Res. 633, 197-205.
36. Mendis D. B., Malaval L., and Brown I. R. (1995) SPARC, an extracellular matrix glycoprotein containing the follistatin module, is expressed by astrocytes in synaptic enriched regions of the adult brain. Brain Res. 676, 69-79.
37. Molina F., Bouanani M., Pau B., and Granier C. (1996) Characterization of the type-1 repeat from thyroglobulin, a cysteine-rich module found in proteins from different families. Eur. J. Biochem. 240, 125-133.
38. Nagase T., Seki N., Ishikawa K., Ohira M., Kawarabayasi Y., Ohara O., Tanaka A., Kotani H., Miyajima N., and Nomura N. (1996) Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res. 3, 321-329.
39. Nielsen H., Engelbrecht J., Brunak S., and van Heijne O. (1997) Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10, 1-6.
40. Oohira A., Katoh-Semba R., Watanabe E., and Matsui F. (1994) Brain development and multiple molecular species of proteoglycan. Neurosci. Res. 20, 195-207.
41. Patel K., Connolly D. J., Amthor H., Nose K., and Cooke J. (1996) Cloning and early dorsal axial expression of Flik, a chick follistatin-related gene: evidence for involvement in dorsalization/neural induction. Dev. Biol. 178, 327-342.
42. Pumain R. and Heinemann U. (1985) Stimulus- and amino acid-induced calcium and potassium changes in rat neocortex. J. Neurophysiol. 53, 1-16.
43. Ruegg M. A. and Bixby J. L. (1998) Agrin orchestrates synaptic differentiation at the vertebrate neuromuscular junction. Trends Neurosci. 21, 22-27.
44. Ruoslahti E. (1996) Brain extracellular matrix. Glycobiology 6, 489-492.
45. Ruoslahti E. and Yamaguchi Y. (1991) Proteoglycans as modulators of growth factor activities. Cell 64, 867-869.
46. Sasaki T., Hohenester E., Göhring W., and Timpl R. (1998) Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/ osteonectin. EMBO J. 17, 1625-1634.
47. Schäfer B. W. and Heizmann C. W. (1996) The SlOO family of EF-hand calcium-binding proteins; functions and pathology. Trends Biochem. 21, 134-140.
48. Schlessinger J., Lax I., and Lemmon M. (1995) Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors? Cell 83, 357-360.
49. van de Graaf S. A. R., Pauws E., de Vijlder J. J. M., and Ris-Stalpers C. (1997) The revised 8,307 basepair coding sequence of human thyroglobulin transiently expressed in eukaryotic cells. Eur. J. Endocrinol. 136, 508-515.
50. Werther G. A., Russo V., Baker N., and Butler G. (1998) The role of the insulin-like growth factor system in the developing brain. Horm. Res. 1, 37-40.