Chondroitin sulfate proteoglycans as mediators of axon growth and pathfinding

Cell and Tissue Research

Volumn 290, Issue 2, 1997, Pages 343-348

  Margolis, Richard U ^a   Margolis, Renée K ^b  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

Neural cell adhesion molecules; Neurocan; Oligosaccharides; Phosphacan; Tenascin C

Indexed keywords

BIGLYCAN; PROTEOCHONDROITIN SULFATE; VERSICAN;

ARTICLE; CELL INTERACTION; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; NEURITE; PRIORITY JOURNAL;

ANIMALS; AXONS; CELL COMMUNICATION; CELL MOVEMENT; HUMANS; LECTINS, C-TYPE; NERVE TISSUE PROTEINS; NERVOUS SYSTEM; NEURONS; PROTEOCHONDROITIN SULFATES;

FELIS CATUS;

EID: 0030730256     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410050939     Document Type: Article

References (45)

1. Balsamo J, Ernst H, Zanin MKB, Hoffman S, Lilien J (1995) The interaction of the retina cell surface N-acetylgalactosaminyl-phosphotransferase with an endogenous proteoglycan ligand results in inhibition of cadherin-mediated adhesion. J Cell Biol 129:1391-1401
2. Bicknese AR, Sheppard AM, O'Leary DDM, Pearlman AL (1994) Thalamocortical axons extend along a chondroitin sulfate protcoglycan-enriched pathway coincident with the neocortical subplate and distinct from the efferent path. J Neurosci 14:3500-3510
3. Brittis PA, Silver J (1994) Exogenous glycosaminoglycans induce complete inversion of retinal ganglion cell bodies and their axons within the retinal neuroepithelium. Proc Natl Acad Sci USA 91:7539-7542
4. Brümmendorf T, Rathjen FG (1995) Cell adhesion molecules I: immunoglobulin superfamily. Protein Profile 2:963-1108
5. Dou C-L, Levine JM (1994) Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan. J Neurosci 14:7616-7628
6. Emerling DE, Lander AD (1996) Inhibitors and promoters of thalamic neuron adhesion and outgrowth in embryonic neocortex: functional association with chondroitin sulfate. Neuron 17: 1089-1100
7. Engel M, Maurel P, Margolis RU, Margolis RK (1996) Chondroitin sulfate proteoglycans in the developing central nervous system. I. Cellular sites of synthesis of neurocan and phosphacan. J Comp Neurol 366:34-43
8. Faissner A, Clement A, Lochter A, Streit A, Mandl C, Schachner M (1994) Isolation of a neural chondroitin sulfate proteoglycan with neurite outgrowth promoting properties. J Cell Biol 126:783-799
9. Friedlander D, Milev P, Karthikeyan L, Margolis RK, Margolis RU, Grumet M (1994) The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM and inhibits neuronal adhesion and neurite outgrowth. J Cell Biol 125:669-680
10. Grumet M, Flaccus A, Margolis RU (1993) Functional characterization of chondroitin sulfate proteoglycans of brain: interactions with neurons and neural cell adhesion molecules. J Cell Biol 120:815-824
11. Grumet M, Milev P, Sakurai T, Karthikeyan L, Bourdon M, Margolis RK, Margolis RU (1994) Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue. J Biol Chem 269:12142-12146
12. Harigaya T, Ogawa H, Tsunoda S, Nagasawa H (1996) The mRNA expression of neurocan, a brain-specific chondroitin sulfate proteoglycan, in neoplastic mammary glands in mice. Zool Sci 13:665-668
13. Hockfield S, McKay RDG (1983) A surface antigen expressed by a subset of neurons in the vetebrate central nervous system. Proc Natl Acad Sci USA 80:5758-5761
14. Höke A, Silver J (1996) Proteoglycans and other repulsive molecules in glial boundaries during development and regeneration of the nervous system. Prog Brain Res 108:149-163
15. Iozzo RV, Murdoch AD (1996) Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function. FASEB J 10:598-614
16. Jhaveri S, Hoffman-Kim D (1996) Unilateral containment of retinal axons by tectal glia: a possible role for sulfated proteoglycans. Prog Brain Res 108:135-148
17. Koops A, Kappler J, Junghans U, Kuhn HG, Kresse H, Müller HW (1996) Cultured astrocytes express biglycan, a chondroitin/dermatan sulfate proteoglycan supporting the survival of neocortical neurons. Mol Brain Res 41:65-73
18. Lander C, Kind P, Maleski M, Hockfield S (1997) A family of activity-dependent neuronal cell-surface chondroitin sulfate proteoglycans in cat visual cortex. J Neurosci 17:1928-1939
19. Landolt RM, Vaughan L, Winterhalter KH, Zimmermann DR (1995) Versican is selectively expressed in embryonic tissues that act as barriers to neural crest cell migration and axon outgrowth. Development 121:2303-2312
20. Levine JM, Nishiyama A (1996) The NG2 chondroitin sulfate proteoglycan: a multifunctional proteoglycan associated with immature cells. Perspect Dev Neurobiol 3:245-259
21. Levy JB, Canoll PD, Silvennoinen O, Barnea G, Morse B, Honegger AM, Haung J-T, Cannizzaro LA, Park S-H, Druck T, Huebner K, Sap J, Ehrlich M, Musacchio JM, Schlessinger J (1993) Thecloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system. J Biol Chem 268:10573-10581
22. Maeda N, Noda M (1996) 6B4 proteoglycan/phosphacan is a repulsive substratum but promotes morphological differentiation of cortical neurons. Development 122:647-658
23. Maeda N, Nishiwaki T, Shintani T, Hamanaka H, Noda M (1996) 6B4 proteoglycan/phosphacan, an extracellular variant of receptor-like protein-tyrosine phosphatase ζ/RPTPβ, binds pleiotrophin/heparin-binding growth-associated molecule (HB-GAM). J Biol Chem 271:21446-21452
24. Margolis RK, Rauch U, Maurel P, Margolis RU (1996) Neurocan and phosphacan: two major nervous tissue-specific chondroitin sulfate proteoglycans. Perspect Dev Neurobiol 3:273-290
25. Maurel P, Rauch U, Flad M, Margolis RK, Margolis RU (1994) Phosphacan, a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell adhesion molecules, is an extracellular variant of a receptor-type protein tyrosine phosphatase. Proc Natl Acad Sci USA 91:2512-2516
26. Meyer-Puttlitz B, Milev P, Junker E, Zimmer I, Margolis RU, Margolis RK (1995) Chondroitin sulfate and chondroitin/keratan sulfate proteoglycans of nervous tissue: developmental changes of neurocan and phosphacan. J Neurochem 65:2327-2337
27. Meyer-Puttlitz B, Junker E, Margolis RU, Margolis RK (1996) Chondroitin sulfate proteoglycans in the developing central nervous system. II. Immunocytochemical localization of neurocan and phosphacan. J Comp Neurol 366:44-54
28. Milev P, Friedlander DR, Sakurai T, Karthikeyan L, Flad M, Margolis RK, Grumet M, Margolis RU (1994) Interactions of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type protein tyrosine phosphatase, with neurons, glia, and neural cell adhesion molecules. J Cell Biol 127:1703-1715
29. Milev P, Meyer-Putllitz B, Margolis RK, Margolis RU (1995) Complex-type asparagine-linked oligosaccharides on phosphacan and protein-tyrosine phosphatase-ζ/β mediate their binding to neural cell adhesion molecules and tenascin. J Biol Chem 270:24650-24653
30. Milev P, Maurel P, Häring M, Margolis RK, Margolis RU (1996) TAG-1/axonin-1 is a high-affinity ligand of neurocan, phosphacan/protein tyrosine phosphatase-ζ/β and N-CAM. J Biol Chem 271:15716-15723
31. Milev P, Fischer D, Häring M, Schulthess T, Margolis RK, Chiquet-Ehrismann R, Margolis RU (1997) The fibrinogen-like globe of tenascin-C mediates its interactions with neurocan and phosphacan/protein tyrosine phosphatase-ζ/β. J Biol Chem 272:15501-15509
32. Miller B, Sheppard AM, Bicknese AR, Pearlman AL (1995) Chondroitin sulfate proteoglycans in the developing cerebral cortex: the distribution of neurocan distinguishes forming afferent and efferent axonal pathways. J Comp Neurol 355:615-628
33. Nishiyama A, Dahlin KJ, Prince JT, Johnstone SR, Stallcup WB (1991) The primary structure of NG2, a novel membrane-spanning proteoglycan. J Cell Biol 114:359-371
34. Oohira A, Matsui F, Watanabe K, Kushima Y, Maeda N (1994) Developmentally regulated expression of a brain specific species of chondroitin sulfate proteoglycan, neurocan, identified with a monoclonal antibody 1G2 in the rat cerebrum. Neuroscience 60:145-157
35. Pearlman AL, Sheppard AM (1996) Extracellular matrix in early cortical development. Prog Brain Res 108:119-134
36. Peles E, Nativ M, Campbell PL, Sakurai T, Martinez R, Lev S, Clary DO, Schilling J, Barnea G, Plowman GD, Grumet M, Schlessinger J (1995) The carbonic anhydrase domain of receptor tyrosine phosphatase β is a functional ligand for the axonal cell recognition molecule contactin. Cell 82:251-260
37. Rauch U, Gao P, Janetzko A, Flaccus A, Hilgenberg L, Tekotte H, Margolis RK, Margolis RU (1991) Isolation and characterization of developmentally-regulated chondroitin sulfate and chondroitin/keratan sulfate proteoglycans of brain identified with monoclonal antibodies. J Biol Chem 266:14785-14801
38. Rauch U, Karthikeyan L, Maurel P, Margolis RU, Margolis RK (1992) Cloning and primary structure of neurocan, a developmentally regulated, aggregating chondroitin sulfate proteoglycan of brain. J Biol Chem 267:19536-19547
39. Sakurai T, Friedlander DR, Grumet M (1996) Expression of polypeptide variants of receptor-type protein tyrosine phosphatase β: the secreted form, phosphacan, increases dramatically during embryonic development and modulates glial cell behavior in vitro. J Neurosci Res 43:694-706
40. Sakurai T, Lustig M, Nativ M, Hemperly JJ, Schlessinger J, Peles E, Grumet M (1997) Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase β. J Cell Biol 136:907-918
41. Schwartz NB, Domowicz M, Krueger RC Jr, Li H, Mangoura D (1996) Brain aggrecan. Perspect Dev Neurobiol 3:291-306
42. Snow DM, Letourneau PC (1992) Neurite outgrowth on a step gradient of chondroitin sulfate proteoglycan. J Neurobiol 23:322-336
43. Snow DM, Brown EM, Letourneau PC (1996) Growth cone behavior in the presence of soluble chondroitin sulfate proteoglycan (CSPG), compared to behavior on CSPG bound to laminin or fibronectin. Int J Dev Neurosci 14:331-349
44. Tillet E, Ruggiero F, Nishiyama A, Stallcup WB (1997) The membrane-spanning proteoglycan NG2 binds to collagens V and VI through the central nonglobular domain of its core protein. J Biol Chem 272:10769-10776
45. Vielmetter J, Stolze B, Bonhoeffer F, Stuermer CAO (1990) In vitro assay to test differential substrate affinities of growing axons and migratory cells. Exp Brain Res 81:283-287