The role of the insulin-like growth factor system in the developing brain

Hormone Research

Volumn 49, Issue SUPPL. 1, 1998, Pages 37-40

  Werther, George A ^a   Russo, Vincenzo ^a   Baker, Naomi ^a   Butler, Gary ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

Apoptosis; Brain development; IGFBPs; IGFs; Neuronal survival; Olfactory bulb

Indexed keywords

PROTEOGLYCAN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

BRAIN DEVELOPMENT; BRAIN GROWTH; CELL SURVIVAL; CONFERENCE PAPER; GLIOSIS; NERVE CELL; NONHUMAN; OLFACTORY BULB; OLIGODENDROGLIA; ORGAN CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR AFFINITY; RECEPTOR BINDING;

EID: 0031910476     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000053066     Document Type: Conference Paper

References (28)

1. Jones JI, Clemmons DR: Insulin-like growth factors and their binding protein: Biological actions. Endocr Rev 1995;16:3-34.
2. Bach LA, Rechler MM: Insulin-like growth factor binding proteins. Diabetes Rev 1995;3:38-61.
3. Clemmons DR: The role of insulin-like growth factor binding protein in controlling the expression of IGF actions; in LeRoith S, Raizada MK (eds): Molecular and Cellular Biology of Insulin-Like Growth Factors and Their Receptors. New York, Plenum, 1989, pp 381-394.
4. Beck KD, Powell-Braxton L, Wildmer HR, Valverde J, Hefti F: IGF-1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons. Neuron 1995;14:17-30.
5. D'Ercole AJ, Dai Z, Xing Y, Boney C, Wilkie MB, Lauder JM, Han VK, Clemmons DR: Brain growth retardation due to expression of hIGFBP-1 in transgenic mice. Dev Brain Res 1994;82:213.
6. Carson MJ: IGF-1 increases brain growth and CNS myelination in transgenic mice. Neuron 1993;10:729.
7. Lesniak MA, Hill JM, Kiess W, Rojeski M, Pert CA, Roth J: Receptors for insulin-like growth factors I and II: Autoradiographic localisation in rat brain and comparison to receptors for insulin. Endocrinology 1988; 123: 2089-2099.
8. Goodyer CG, De Stephano L, Hsien LW, Guyda HJ, Posner BI: Characterization of insulin-like growth factor receptors in rat anterior pituitary, hypothalamus and brain. Endocrinology 1984;114:1187-1195.
9. Bondy CA, Werner H, Roberts CT, Le Roith D: Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: Comparison with insulin-like growth factor I and II. Neuroscience 1992; 46:909-923.
10. Hynes M, Brooks PJ, Van Wyk JJ, Lund PK: Insulin-like growth factor II messenger ribonucleic acids are synthesized in the choroid plexus in the rat brain. Mol Endocrinology 1988;2:47-54.
11. Rotwein P, Burgess SK, Milbrandt JD, Krause JE: Differential expression of IGF genes in rat CNS. Proc Natl Acad Sci USA 1988;85:265-269.
12. Werther GA, Abate M, Hogg A, Cheesman H, Oldfield B, Hards D, Hudson P, Power B, Freed K, Herington AC: Localization of insulin-like growth factor-I mRNA in rat brain by in situ hybridization - Relationship to IGF-I receptors. Mol Endocrinol 1990;4:773-778.
13. Lee WH, Michels KM, Bondy CA: Localization of insulin-like growth factor binding protein-2 messenger RNA during post-natal brain development: Correlation with insulin-like growth factor I and II. Neuroscience 1993;53: 251-265.
14. Bondy C, Lee WH: Correlation between insulin-like growth factor (IGF)-binding protein 5 and IGF-I expression during brain development. J Neurosci 1993;13:5092-5104.
15. Russo VC, Edmondson SR, Mercuri FA, Buchanan CR, Werther GA: Identification, localisation and regulatin of insulin-like growth factor binding proteins and their messenger RNAs in newborn rat olfactory bulb. Endocrinology 1994;135:1437-1446.
16. Russo VC, Bach LA, Werther GA: Cell membrane association of insulin-like growth factor binding protein-2 in the rat brain olfactory bulb. Prog Growth Factor Res 1996;6:329-336.
17. Pons S, Torres-Aleman I: Basic fibroblast growth factor modulates insulin-like growth factor-I, its receptor, and its binding proteins in hypothalamic cell cultures. Endocrinology 1992;131:2271-2278.
18. Recio-Pinto E, Rechler MM, Ishi DN: Effects of insulin, insulin-like growth factor II and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons. J Neurosci 1986;6:1211-1219.
19. Werther GA, Cheesman H, Russo VC: Olfactory bulb organ culture is supported by combined insulin-like growth factor-I and basic fibroblast growth factor. Brain Res 1993;617:339-342.
20. Schwartzman RA: Apoptosis: the biochemistry and molecular biology. Endocr Rev 1993;14: 133-151.
21. Oppenheim RW: Cell death during development of the nervous system. Annu Rev Neurosci 1991;14:453-501.
22. Hockenberry DM: Bcl-2 protein is topographically restricted in apoptotic tissues. Proc Natl Acad Sci USA 1991;88:6961-6965.
23. D'Mello SR, Galli C, Ciotti T, Calissano P: Induction of apoptosis in cerebellar granule neurons by low potassium. Proc Natl Acad Sci USA 1993;90:10989.
24. Barres BA: Cell death and control of cell survival in the oligodendrocyte lineage. Cell 1992; 70:31-46.
25. Trojan J: Loss of tumorigenicity of rat glioblastoma directed by episome-based cDNA transcription of IGF-1. Proc Natl Acad Sci USA 1992;89:4874.
26. Ambrose D: Growth regulation of glioblastoma T98G cells by IGF-I and its receptor. J Cell Physiol 1994;159:92-100.
27. Williams CE, Skinner SJM, Beilharz E, Guan J, Sirimanne E, Dragunow M, Gluckman PD: IGF and the brain; in Cowell C, Ho K, Werther GA (eds): Growth and Sexual Development. New York, Harwood Academic Press, 1993.
28. Russo VC, Werther GA: Des (1-3) IGF-I potently enhances cell growth in olfactory bulb organ culture. Growth Factors 1994;11:301.