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Volumn 19, Issue 3, 2003, Pages 161-176

Interaction between fibrates and statins-metabolic interactions with gemfibrozil

Author keywords

Cerivastatin; Fibrates; Gemfibrozil; HMG CoA reductase inhibitor; Pitavastatin

Indexed keywords

ATORVASTATIN; BEZAFIBRATE; CERIVASTATIN; CIPROFIBRATE; CLOFIBRATE; CYTOCHROME P450; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; FENOFIBRATE; FIBRIC ACID DERIVATIVE; FLUINDOSTATIN; GEMFIBROZIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PITAVASTATIN; STATINE;

EID: 0344307424     PISSN: 07925077     EISSN: None     Source Type: Journal    
DOI: 10.1515/DMDI.2003.19.3.161     Document Type: Article
Times cited : (20)

References (29)
  • 2
    • 0032822196 scopus 로고    scopus 로고
    • Hypolipidemic effect of NK-104, a potent HMG-CoA reductase inhibitor, in guinea pigs
    • Suzuki H, Aoki T, Tamaki T, Sato F, Kitahara M, Saito Y. Hypolipidemic effect of NK-104, a potent HMG-CoA reductase inhibitor, in guinea pigs. Atherosclerosis 1999; 146: 259-270.
    • (1999) Atherosclerosis , vol.146 , pp. 259-270
    • Suzuki, H.1    Aoki, T.2    Tamaki, T.3    Sato, F.4    Kitahara, M.5    Saito, Y.6
  • 3
    • 0035139148 scopus 로고    scopus 로고
    • Hypolipidemic effect of NK-104 and other 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in guinea pigs
    • Suzuki H, Yamazaki H, Aoki T, Tamaki T, Sato F, Kitahara M, Saito Y. Hypolipidemic effect of NK-104 and other 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in guinea pigs. Arzneim Forsch/Drug Res 2001; 51: 38-45.
    • (2001) Arzneim Forsch/Drug Res , vol.51 , pp. 38-45
    • Suzuki, H.1    Yamazaki, H.2    Aoki, T.3    Tamaki, T.4    Sato, F.5    Kitahara, M.6    Saito, Y.7
  • 4
    • 0033758172 scopus 로고    scopus 로고
    • NK-104, a novel synthetic HMG-CoA reductase inhibitor
    • Kajinami K, Mabuchi H, Saito Y. NK-104, a novel synthetic HMG-CoA reductase inhibitor. Exp Opin Invest Drugs 2000; 9: 2653-2661.
    • (2000) Exp Opin Invest Drugs , vol.9 , pp. 2653-2661
    • Kajinami, K.1    Mabuchi, H.2    Saito, Y.3
  • 6
    • 0035811194 scopus 로고    scopus 로고
    • Simultaneous determination of taxol and its metabolites in microsomal samples by a simple thin layer chromatography assay - Inhibitory effect of NK-104, a new inhibitor of HMG-CoA reductase
    • Fujino H, Yamada I, Shimada S, Yoneda M. Simultaneous determination of taxol and its metabolites in microsomal samples by a simple thin layer chromatography assay - inhibitory effect of NK-104, a new inhibitor of HMG-CoA reductase. J Chromatogr B 2001; 757: 143-150.
    • (2001) J Chromatogr B , vol.757 , pp. 143-150
    • Fujino, H.1    Yamada, I.2    Shimada, S.3    Yoneda, M.4
  • 7
    • 0036406733 scopus 로고    scopus 로고
    • The metabolic fate of pitavastatin (NK-104), a new inhibitor of HMG-CoA reductase: Effects on drug-metabolizing systems in rats and humans
    • Fujino H, Yamada I, Shimada S, Yoneda M. The metabolic fate of pitavastatin (NK-104), a new inhibitor of HMG-CoA reductase: effects on drug-metabolizing systems in rats and humans. Arzneim Forsch/Drug Res 2002; 52: 745-753.
    • (2002) Arzneim Forsch/Drug Res , vol.52 , pp. 745-753
    • Fujino, H.1    Yamada, I.2    Shimada, S.3    Yoneda, M.4
  • 10
    • 0034951964 scopus 로고    scopus 로고
    • Severe rhabdomyolysis accociated with the cerivastatin-gemfibrozil combination therapy: Report of a case
    • Lau TK, Leachman DR, Lufschanowski R. Severe rhabdomyolysis accociated with the cerivastatin-gemfibrozil combination therapy: report of a case. Tex Heart Inst J 2001; 28: 142-145.
    • (2001) Tex Heart Inst J , vol.28 , pp. 142-145
    • Lau, T.K.1    Leachman, D.R.2    Lufschanowski, R.3
  • 11
    • 0035434397 scopus 로고    scopus 로고
    • Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins)
    • Igel M, Sudhop T, Bergmann K. Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins). Eur J Clin Pharmacol 2001; 57: 357-364.
    • (2001) Eur J Clin Pharmacol , vol.57 , pp. 357-364
    • Igel, M.1    Sudhop, T.2    Bergmann, K.3
  • 12
    • 0032005257 scopus 로고    scopus 로고
    • Rhabdomyolysis after taking atorvastatin with gemfibrozil
    • Duell PB, Connor WE, Ilingworth DR. Rhabdomyolysis after taking atorvastatin with gemfibrozil. Am J Cardiol 1998; 81: 368-369.
    • (1998) Am J Cardiol , vol.81 , pp. 368-369
    • Duell, P.B.1    Connor, W.E.2    Ilingworth, D.R.3
  • 13
    • 0033900967 scopus 로고    scopus 로고
    • A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil conbination therapy - A case report
    • Ozdemir O, Boran M, Gokce V, Uzun Y, Kocak B, Korkmaz S. A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil conbination therapy - a case report. Angiology 2000; 51: 695-697.
    • (2000) Angiology , vol.51 , pp. 695-697
    • Ozdemir, O.1    Boran, M.2    Gokce, V.3    Uzun, Y.4    Kocak, B.5    Korkmaz, S.6
  • 15
    • 0035337643 scopus 로고    scopus 로고
    • Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate
    • Kyrklund C, Backman JT, Kivisto KT, Neuvonen M, Laitila J, Neuvonen PJ. Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate. Clin Pharmacol Ther 2001; 69: 340-345.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 340-345
    • Kyrklund, C.1    Backman, J.T.2    Kivisto, K.T.3    Neuvonen, M.4    Laitila, J.5    Neuvonen, P.J.6
  • 17
    • 0001224909 scopus 로고    scopus 로고
    • Studies on the metabolic fate of NK-104, a new inhibitor HMG-CoA reductase (5): In vitro metabolism and plasma protein binding in animals and human
    • Fujino H, Yamada I, Hirano M, Kojima J, Matsumoto H, Yoneda M. Studies on the metabolic fate of NK-104, a new inhibitor HMG-CoA reductase (5): In vitro metabolism and plasma protein binding in animals and human. Xenobio Metab Dispos 1999; 14: 415-424.
    • (1999) Xenobio Metab Dispos , vol.14 , pp. 415-424
    • Fujino, H.1    Yamada, I.2    Hirano, M.3    Kojima, J.4    Matsumoto, H.5    Yoneda, M.6
  • 18
    • 0031736655 scopus 로고    scopus 로고
    • Metabolism and drug interactions. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor in transplant patients: Are the statins mechanistically similar?
    • Christians U, Jacobsen W, Floren L. Metabolism and drug interactions. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor in transplant patients: Are the statins mechanistically similar? Pharmacol Ther 1998; 80: 1-34.
    • (1998) Pharmacol Ther , vol.80 , pp. 1-34
    • Christians, U.1    Jacobsen, W.2    Floren, L.3
  • 19
    • 0028350990 scopus 로고
    • Application of radioluminography to off-line counting of radioactivity in high-performance liquid chromatographic elutes
    • Baba S, Terasawa Y, Kimata H, Shinohara Y, Akira K, Hasegawa H. Application of radioluminography to off-line counting of radioactivity in high-performance liquid chromatographic elutes. J Chromatogr A 1994; 663: 35-41.
    • (1994) J Chromatogr A , vol.663 , pp. 35-41
    • Baba, S.1    Terasawa, Y.2    Kimata, H.3    Shinohara, Y.4    Akira, K.5    Hasegawa, H.6
  • 20
    • 0000332988 scopus 로고    scopus 로고
    • Studies on the metabolic fate of NK-104, a new inhibitor of HMG-CoA reductase (1): Absorption, distribution, metabolism and excretion in rats
    • Kimata H, Fujino H, Koide T, Yamada Y, Tsunenari Y, Yanagawa Y. Studies on the metabolic fate of NK-104, a new inhibitor of HMG-CoA reductase (1): Absorption, distribution, metabolism and excretion in rats. Xenobio Metab Dispos 1998; 13: 484-498.
    • (1998) Xenobio Metab Dispos , vol.13 , pp. 484-498
    • Kimata, H.1    Fujino, H.2    Koide, T.3    Yamada, Y.4    Tsunenari, Y.5    Yanagawa, Y.6
  • 21
    • 0032734030 scopus 로고    scopus 로고
    • Quantitation of cerivastatin and its seven acid and lactone biotransformation products in human serum by liquid chromatography-electrospray tandem mass spectrometry
    • Jemal M, Rao S, Salahudeen I, Chen BC, Kates R. Quantitation of cerivastatin and its seven acid and lactone biotransformation products in human serum by liquid chromatography-electrospray tandem mass spectrometry. J Chromatogr B 1999; 736: 19-41.
    • (1999) J Chromatogr B , vol.736 , pp. 19-41
    • Jemal, M.1    Rao, S.2    Salahudeen, I.3    Chen, B.C.4    Kates, R.5
  • 22
    • 0032996183 scopus 로고    scopus 로고
    • Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry
    • Jemal M, Ouyang Z, Chen BC, Teitz D. Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry. Rapid Commun Mass Spectrom 1999; 13: 1003-1015.
    • (1999) Rapid Commun Mass Spectrom , vol.13 , pp. 1003-1015
    • Jemal, M.1    Ouyang, Z.2    Chen, B.C.3    Teitz, D.4
  • 23
    • 0031766228 scopus 로고    scopus 로고
    • High-performance liquid chromatographic method for the determination of fenofibric acid and reduced fenofibric acid in human blood, plasma and urine
    • Abe S, Ono K, Mogi M, Hayashi T. High-performance liquid chromatographic method for the determination of fenofibric acid and reduced fenofibric acid in human blood, plasma and urine. Yakugaku Zasshi 1998; 118: 447-455.
    • (1998) Yakugaku Zasshi , vol.118 , pp. 447-455
    • Abe, S.1    Ono, K.2    Mogi, M.3    Hayashi, T.4
  • 24
    • 0032502948 scopus 로고    scopus 로고
    • Assessment of microsomal tolbutamide hydroxylation by a simple thin-layer chromatography radioactivity assay
    • Ludwig E, Wolfinger H, Ebner T. Assessment of microsomal tolbutamide hydroxylation by a simple thin-layer chromatography radioactivity assay. J Chromatogr B 1998; 707: 347-350.
    • (1998) J Chromatogr B , vol.707 , pp. 347-350
    • Ludwig, E.1    Wolfinger, H.2    Ebner, T.3
  • 25
    • 0032937343 scopus 로고    scopus 로고
    • The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: Effect on human cytochrome P-450 and implications for metabolic drug interactions
    • Fischer V, Johanson L, Heitz F, Tullman R, Graham E, Baldeck JP, Robinson WT. The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions. Drug Metab Dispos 1999; 27: 410-416.
    • (1999) Drug Metab Dispos , vol.27 , pp. 410-416
    • Fischer, V.1    Johanson, L.2    Heitz, F.3    Tullman, R.4    Graham, E.5    Baldeck, J.P.6    Robinson, W.T.7
  • 27
    • 0033831429 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of cerivastatin
    • Mück W. Clinical pharmacokinetics of cerivastatin. Clin Pharmacokinet 2000; 39: 99-116.
    • (2000) Clin Pharmacokinet , vol.39 , pp. 99-116
    • Mück, W.1
  • 28
    • 0034837148 scopus 로고    scopus 로고
    • Assessment of drug-drug interactions: Concepts and approaches
    • Weaver RJ. Assessment of drug-drug interactions: concepts and approaches. Xenobiotica 2001; 31: 499-538.
    • (2001) Xenobiotica , vol.31 , pp. 499-538
    • Weaver, R.J.1


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