A functionalized THz sensor for marker-free DNA analysis

Physics in Medicine and Biology

Volumn 48, Issue 22, 2003, Pages 3625-3636

  Nagel, M ^a   Richter, F ^a   Haring Bolivar P ^a   Kurz, H ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOSENSORS; DNA SEQUENCES; ELECTRODES; MOLECULAR BIOLOGY; PHOTOCONDUCTIVITY;

HYBRIDIZATION;

BIOMEDICAL ENGINEERING;

DNA MARKER; SINGLE STRANDED DNA;

ARTICLE; BINDING AFFINITY; BIOSENSOR; CONTROLLED STUDY; DNA DETERMINATION; DNA HYBRIDIZATION; DNA MICROARRAY; DNA PROBE; DNA SEQUENCE; ELECTRODE; GENE TARGETING; PRIORITY JOURNAL; SAMPLING; SENSITIVITY AND SPECIFICITY; TIME;

BIOSENSING TECHNIQUES; DNA PROBES; ELECTRODES; NUCLEIC ACID HYBRIDIZATION; SENSITIVITY AND SPECIFICITY; SPECTRUM ANALYSIS;

EID: 0344271783     PISSN: 00319155     EISSN: None     Source Type: Journal    
DOI: 10.1088/0031-9155/48/22/001     Document Type: Article

References (27)

1. Abegaonkar M P, Karekar R N and Aiyer R C 1999 A microwave microstrip ring resonator as a moisture sensor for biomaterials: application to wheat grains Meas. Sci. Technol. 10 195-200
2. Auston D H 1983 Impulse response of photoconductors in transmission lines IEEE J. Quantum Electron. 19 639
3. Bernard P A and Gautray J M 1991 Measurement of dielectric constant using a microstrip ring resonator IEEE Trans. Microw. Theory Tech. 39 592-5
4. Brucherseifer M, Haring-Bolívar P and Kurz H 2002 Combined optical and spatial modulation THz-spectroscopy for the analysis of thin-layered systems Appl. Phys. Lett. 81 1791-3
5. Brucherseifer M, Nagel M, Haring-Bolívar P, Kurz H, Bosserhoff A and Büttner R 2000 Label-free probing of the binding state of DNA by time-domain terahertz sensing Appl. Phys. Lett. 77 4049-51
6. Curtis J A and Fiedziuszko S J 1991 Miniature dual mode microstrip filters IEEE MTT-S Int. Microw. Symp. Dig. 2 443-6
7. Fischer B M, Walther M and Uhd Jepsen P 2002 Far-infrared vibrational modes of DNA components studied by terahertz time-domain spectroscopy Phys. Med. Biol. 47 3807-14
8. Herne T M and Tarlov M J 1997 J. Am. Chem. Soc. 119 8916-20
9. Himmel H-J, Terfort A, Arnold R and Wöll C 1999 Mater. Sci. Eng. C 8-9 431-5
10. Keil U D and Hvam J M 1997 Femtosecond differential transmission measurements on low temperature GaAs metal-semiconductor-metal structures Appl. Phys. Lett. 70 73-4
11. Larramendy M L, El-Rifai W and Knuutila 1998 Comparison of fluorescein isothiocyanate- and Texas red-conjugated nucleotides for direct labeling in comparative genomic hybridization Cytometry 31 174-9
12. Lu S L and Ferendeci A M 1996 Varactor tuned ring resonator microwave oscillator Electron. Lett. 32 46-8
13. Levicky R, Herne T M, Tarlov M J and Satija S K 1998 J. Am. Chem. Soc. 120 9787-92
14. Mongia R, Bahl I and Bhartia P 1999 RF and Microwave Coupled-Line Circuits (Boston: Artech House)
15. Nagel M, Dekorsy T and Kurz H 2002a Microstrip for Microwave Applications. Patent specification, EP 1205005
16. Nagel M, Haring-Bolívar P, Brucherseifer M, Kurz H, Bosserhoff A and Büttner R 2002b Integrated THz technology for label-free genetic diagnostics Appl. Phys. Lett. 80 154-6
17. Nagel M, Dekorsy T, Brucherseifer M, Haring-Bolívar P and Kurz H 2001 Characterization of polypropylene thin-film microstrip lines at millimeter and submillimeter wavelengths Microw. Opt. Technol. Lett. 29 97-100
18. Ozaki H and McLaughlin L W 1992 The estimation of distances between specific backbone-labeled sites in DNA using fluorescence resonance energy transfer Nucleic Acids Res. 20 5205-14
19. Pawlak H, Jannsen B and Jacok A F 2002 Systematic design of resonant microstrip sensors with sensitive coating Microw. Opt. Technol. Lett. 32 21-5
20. Peterlinz K A, Georgiadis R A, Herne T M and Tarlov M J 1997 J. Am. Chem. Soc. 119 3401-2
21. Pfeifer T, Heiliger H-M, Löffler T, Ohlhoff C, Meyer C, Lüpke G, Roskos H G and Kurz H 1996 IEEE J. Sel. Top. Quantum Electron. 2 586
22. Steel A B, Herne T M and Tarlov M J 1998 Anal. Chem. 70 4670-7
23. Troughton P 1969 Measurement technique in microstrip Electron. Lett. 5 25
24. Wang J 2000 From DNA biosensors to gene chips Nucleic Acids Res. 28 3011-6
25. 7-δ microwave ring oscillators Physica B 284-288 2079-80
26. Zhu Z, Chao J, Yu H and Waggoner A S 1994 Directly labeled DNA probes using fluorescent nucleotides with different length linkers Nucleic Acids Res. 22 3418-22
27. Zhu Z and Waggoner A S 1997 Molecular mechanism controlling the incorporation of fluorescent nucleotides into DNA by PCR Cytometry 28 206-11