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Volumn 41, Issue 8, 1999, Pages 693-698

Use of the alkaline comet assay to monitor DNA damage in technicians exposed to low-dose radiation

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BIOLOGICAL MONITORING; CIGARETTE SMOKING; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GEL ELECTROPHORESIS; GENETIC RISK; HUMAN; LOW ENERGY RADIATION; LYMPHOCYTE; MALE; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; ONCOLOGY; RADIATION EXPOSURE; RADIOLOGICAL TECHNOLOGIST;

EID: 0344132658     PISSN: 10762752     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043764-199908000-00012     Document Type: Article
Times cited : (19)

References (36)
  • 1
    • 0025165697 scopus 로고
    • Induction repair and biological relevance of radiation-induced DNA lesions in eukaryotic cells
    • Frankenberg-Schwager M. Induction repair and biological relevance of radiation-induced DNA lesions in eukaryotic cells. Radiat Environ Biophys. 1990;29: 273-292.
    • (1990) Radiat Environ Biophys. , vol.29 , pp. 273-292
    • Frankenberg-Schwager, M.1
  • 2
    • 0025900687 scopus 로고
    • Delayed reproductive death in X-irradiated Chinese hamster ovary cells
    • Chang WP, Little JB. Delayed reproductive death in X-irradiated Chinese hamster ovary cells. Int J Radiat Biol. 1991; 60:483-496.
    • (1991) Int J Radiat Biol. , vol.60 , pp. 483-496
    • Chang, W.P.1    Little, J.B.2
  • 3
    • 0027464763 scopus 로고
    • Clonal chromosome aberrations and genomic instability in X-irradiated human T-lymphocyte cultures
    • Holmberg K, Falt S, Johansson A, Lambert B. Clonal chromosome aberrations and genomic instability in X-irradiated human T-lymphocyte cultures. Mutat Res. 1993;286:321-330.
    • (1993) Mutat Res. , vol.286 , pp. 321-330
    • Holmberg, K.1    Falt, S.2    Johansson, A.3    Lambert, B.4
  • 4
    • 0030042134 scopus 로고    scopus 로고
    • Role of induced genetic instability in the mutagenic effects of chemicals and radiation
    • Murnane JP. Role of induced genetic instability in the mutagenic effects of chemicals and radiation. Mutat Res. 1996;367:11-23.
    • (1996) Mutat Res. , vol.367 , pp. 11-23
    • Murnane, J.P.1
  • 6
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh NP, McCoy MT, Tice RR, Schneider A. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res. 1988;175: 184-191.
    • (1988) Exp Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, A.4
  • 8
    • 0026751636 scopus 로고
    • Assessment of radiation-induced DNA damage in human blood lymphocytes using the single-cell gel electrophoresis technique
    • Vijayalaxmi, Tice RR, Strauss GHS. Assessment of radiation-induced DNA damage in human blood lymphocytes using the single-cell gel electrophoresis technique. Mutat Res. 1992;271:243-252.
    • (1992) Mutat Res. , vol.271 , pp. 243-252
    • Tice, R.R.1    Strauss, G.H.S.2
  • 9
    • 0027423615 scopus 로고
    • Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay
    • Olive PL, Frazer G, Banath JP. Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay. Radiat Res. 1993;136:130-136.
    • (1993) Radiat Res. , vol.136 , pp. 130-136
    • Olive, P.L.1    Frazer, G.2    Banath, J.P.3
  • 10
    • 0028092855 scopus 로고
    • Modifications of alkaline microgel electrophoresis for sensitive detection of DNA damage
    • Singh NP, Stephens RE, Schneider EL. Modifications of alkaline microgel electrophoresis for sensitive detection of DNA damage. Int J Radiat Biol. 1994;66: 23-28.
    • (1994) Int J Radiat Biol. , vol.66 , pp. 23-28
    • Singh, N.P.1    Stephens, R.E.2    Schneider, E.L.3
  • 11
    • 0344117041 scopus 로고
    • The comet assay: A biomarker for detection of genotoxicity induced by chemicals and radiation
    • Plappert UG, Raddatz K, Rieth W, Fliedner TM. The comet assay: a biomarker for detection of genotoxicity induced by chemicals and radiation. Clin Chem. 1995;41:1911-1913.
    • (1995) Clin Chem. , vol.41 , pp. 1911-1913
    • Plappert, U.G.1    Raddatz, K.2    Rieth, W.3    Fliedner, T.M.4
  • 12
    • 0030882595 scopus 로고    scopus 로고
    • Changes in the repair capacity of blood cells as a biomarker for chronic low-dose exposure to ionizing radiation
    • Plappert UG, Stocker B, Fender H, Fliedner TM. Changes in the repair capacity of blood cells as a biomarker for chronic low-dose exposure to ionizing radiation. Environ Mol Mutagen. 1997;30:153-160.
    • (1997) Environ Mol Mutagen. , vol.30 , pp. 153-160
    • Plappert, U.G.1    Stocker, B.2    Fender, H.3    Fliedner, T.M.4
  • 13
    • 0016961001 scopus 로고
    • Isolation of lymphocytes, granulocytes, and macrophages
    • Boyum A, Isolation of lymphocytes, granulocytes, and macrophages. Scand J Immunol. 1976;5:9-15.
    • (1976) Scand J Immunol. , vol.5 , pp. 9-15
    • Boyum, A.1
  • 14
    • 0028305534 scopus 로고
    • The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the comet assay
    • Anderson D, Yu TW, Phillips BJ, Schmezer P. The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the comet assay. Mutat Res. 1994;307:261-271.
    • (1994) Mutat Res. , vol.307 , pp. 261-271
    • Anderson, D.1    Yu, T.W.2    Phillips, B.J.3    Schmezer, P.4
  • 16
    • 0013983369 scopus 로고
    • Somatic chromosome aberrations induced by human irradiation: The "Recuplex" irradiation accident
    • Bender MA, Gooch PC. Somatic chromosome aberrations induced by human irradiation: the "Recuplex" irradiation accident. Radiat Res. 1966;29:568-582.
    • (1966) Radiat Res. , vol.29 , pp. 568-582
    • Bender, M.A.1    Gooch, P.C.2
  • 17
    • 0025492743 scopus 로고
    • Effects of long-term radiation exposure on chromosomal aberrations in radiological technologists
    • Kumagai E, Tanaka R, Kumagai T, Onomichi M, Sawada S. Effects of long-term radiation exposure on chromosomal aberrations in radiological technologists. Radiat Res. 1990;31:270-279.
    • (1990) Radiat Res. , vol.31 , pp. 270-279
    • Kumagai, E.1    Tanaka, R.2    Kumagai, T.3    Onomichi, M.4    Sawada, S.5
  • 18
    • 0030772013 scopus 로고    scopus 로고
    • Biological dosimetry of radiation workers at the Sellafield nuclear facility
    • Tucker JD, Tawn JE, Holdsworth D, et al. Biological dosimetry of radiation workers at the Sellafield nuclear facility. Radiat Res. 1997;148:216-226.
    • (1997) Radiat Res. , vol.148 , pp. 216-226
    • Tucker, J.D.1    Tawn, J.E.2    Holdsworth, D.3
  • 19
    • 0028644268 scopus 로고
    • Micronuclei and 3AB-index in patients receiving iodine-131 therapy
    • Catena C, Villani P, Nastasi R, et al. Micronuclei and 3AB-index in patients receiving iodine-131 therapy. J Nucl Biol Med. 1994;38:540-547.
    • (1994) J Nucl Biol Med. , vol.38 , pp. 540-547
    • Catena, C.1    Villani, P.2    Nastasi, R.3
  • 20
    • 0029980038 scopus 로고    scopus 로고
    • Cytogenetic study of radiation burden in thyroid disease patients treated with external irradiation or radioiodine
    • Gundy S, Katz N, Füzy M, Esik O. Cytogenetic study of radiation burden in thyroid disease patients treated with external irradiation or radioiodine. Mutat Res. 1996;360:107-113.
    • (1996) Mutat Res. , vol.360 , pp. 107-113
    • Gundy, S.1    Katz, N.2    Füzy, M.3    Esik, O.4
  • 21
    • 0025896668 scopus 로고
    • Biological indicators for radiation damage
    • Muller W, Streffer C. Biological indicators for radiation damage. Int J Radiat Biol. 1991;59:863-873.
    • (1991) Int J Radiat Biol. , vol.59 , pp. 863-873
    • Muller, W.1    Streffer, C.2
  • 22
    • 0026081946 scopus 로고
    • A cytogenetic follow-up study of the victims of a radiation accident in Goiania (Brazil)
    • Natarajan AT, Vyas RC, Wiegant J, Curado MP. A cytogenetic follow-up study of the victims of a radiation accident in Goiania (Brazil). Mutat Res. 1991;247:103-111.
    • (1991) Mutat Res. , vol.247 , pp. 103-111
    • Natarajan, A.T.1    Vyas, R.C.2    Wiegant, J.3    Curado, M.P.4
  • 23
    • 0028970067 scopus 로고
    • Elevated frequency of glycophorin A mutations in erythrocytes from Chernobyl accident victims
    • Jensen RH, Langlois RG, Bigbee WL, et al. Elevated frequency of glycophorin A mutations in erythrocytes from Chernobyl accident victims. Radiat Res. 1995; 141:129-135.
    • (1995) Radiat Res. , vol.141 , pp. 129-135
    • Jensen, R.H.1    Langlois, R.G.2    Bigbee, W.L.3
  • 24
    • 0031724411 scopus 로고    scopus 로고
    • Chromosomal aberrations in medical staff occupationally exposed to X-rays: A follow-up study
    • Kasuba V, Rodzgaj R, Sentija K, Chromosomal aberrations in medical staff occupationally exposed to X-rays: a follow-up study. Arh Hig Rada Toksikol. 1998;49:1-8.
    • (1998) Arh Hig Rada Toksikol. , vol.49 , pp. 1-8
    • Kasuba, V.1    Rodzgaj, R.2    Sentija, K.3
  • 25
    • 0028957715 scopus 로고
    • Somatic cell mutations as a possible predictor of cancer risk
    • Akiyama M, Umeki S, Kusunoki Y, et al. Somatic cell mutations as a possible predictor of cancer risk. Health Phys. 1995; 68:643-649.
    • (1995) Health Phys. , vol.68 , pp. 643-649
    • Akiyama, M.1    Umeki, S.2    Kusunoki, Y.3
  • 26
    • 0029957134 scopus 로고    scopus 로고
    • Somatic cell mutations at the glycophorin A locus in erythrocytes of atomic bomb survivors: Implications for radiation carcinogenesis
    • Kyoizumi S, Akiyama M, Cologne JB, et al. Somatic cell mutations at the glycophorin A locus in erythrocytes of atomic bomb survivors: implications for radiation carcinogenesis. Radiat Res. 1996; 146:43-52.
    • (1996) Radiat Res. , vol.146 , pp. 43-52
    • Kyoizumi, S.1    Akiyama, M.2    Cologne, J.B.3
  • 27
    • 0029868299 scopus 로고    scopus 로고
    • Glycophorin A biodosimetry in Chernobyl cleanup workers from the Baltic countries
    • Bigbee WL. Jensen RH, Viedenbaum T, et al. Glycophorin A biodosimetry in Chernobyl cleanup workers from the Baltic countries. Br Med J. 1996;312:1078-1079.
    • (1996) Br Med J. , vol.312 , pp. 1078-1079
    • Bigbee, W.L.1    Jensen, R.H.2    Viedenbaum, T.3
  • 28
    • 0031049912 scopus 로고    scopus 로고
    • Biodosimetry of Chernobyl cleanup workers using the glycophorin A in vivo somatic cell mutation assay
    • Bigbee WL, Jensen RH, Viedenbaum T, et al. Biodosimetry of Chernobyl cleanup workers using the glycophorin A in vivo somatic cell mutation assay. Radiat Res. 1997;147:215-224.
    • (1997) Radiat Res. , vol.147 , pp. 215-224
    • Bigbee, W.L.1    Jensen, R.H.2    Viedenbaum, T.3
  • 29
    • 0032520973 scopus 로고    scopus 로고
    • Impaired DNA repair as assessed by the "comet" assay in patients with thyroid tumors after a history of radiation therapy: A preliminary study
    • Leprat F, Alapetite C, Roselli F, et al. Impaired DNA repair as assessed by the "comet" assay in patients with thyroid tumors after a history of radiation therapy: a preliminary study. Int J Radiat Oncol Biol Phys. 1998;40:1019-1026.
    • (1998) Int J Radiat Oncol Biol Phys. , vol.40 , pp. 1019-1026
    • Leprat, F.1    Alapetite, C.2    Roselli, F.3
  • 31
    • 0344301939 scopus 로고    scopus 로고
    • Application of the comet assay for monitoring DNA damage in workers exposed to chronic low-dose irradiation: I. Strand breakage
    • Wojewodzka M, Kruszewski M, Iwanenko T, Collins AR, Szumiel I. Application of the comet assay for monitoring DNA damage in workers exposed to chronic low-dose irradiation: I. Strand breakage. Mutat Res. 1998;416:21-35.
    • (1998) Mutat Res. , vol.416 , pp. 21-35
    • Wojewodzka, M.1    Kruszewski, M.2    Iwanenko, T.3    Collins, A.R.4    Szumiel, I.5
  • 32
    • 0031844105 scopus 로고    scopus 로고
    • Comet assay on children's leukocytes 8 years after the Chernobyl disaster
    • Frenzilli G, Lori A, Panasiuk G, Ferdeghini M, Barale R. Comet assay on children's leukocytes 8 years after the Chernobyl disaster. Mutat Res. 1998;415: 151-158.
    • (1998) Mutat Res. , vol.415 , pp. 151-158
    • Frenzilli, G.1    Lori, A.2    Panasiuk, G.3    Ferdeghini, M.4    Barale, R.5
  • 33
    • 0026055975 scopus 로고
    • Basal DNA damage in individual human lymphocytes with age
    • Singh NP, Danner DB, Tice RR, et al. Basal DNA damage in individual human lymphocytes with age. Mutat Res. 1991; 256:1-6.
    • (1991) Mutat Res. , vol.256 , pp. 1-6
    • Singh, N.P.1    Danner, D.B.2    Tice, R.R.3
  • 34
    • 0029085953 scopus 로고
    • Reproducibility of basal and induced DNA single cell gel electrophoresis assay in human peripheral mononuclear leukocytes
    • Holz O, Jörres R, Kastner T, Magnussen H. Reproducibility of basal and induced DNA single cell gel electrophoresis assay in human peripheral mononuclear leukocytes. Int Arch Occup Environ Health. 1995;67:305-310.
    • (1995) Int Arch Occup Environ Health , vol.67 , pp. 305-310
    • Holz, O.1    Jörres, R.2    Kastner, T.3    Magnussen, H.4
  • 35
    • 0344959473 scopus 로고    scopus 로고
    • Assessment of DNA damage in nurses handling antineoplastic drugs by alkaline comet assay
    • Ündeǧer Ü, Başaran N, Kars A, Güc D. Assessment of DNA damage in nurses handling antineoplastic drugs by alkaline comet assay. Mutat Res. 1999;439:277-285.
    • (1999) Mutat Res. , vol.439 , pp. 277-285
    • Ü, U.1    Başaran, N.2    Kars, A.3    Güc, D.4
  • 36
    • 0022642022 scopus 로고
    • Urine mutagenicity, chromosomal abnormalities and sister chromatid exchanges in lymphocytes of nurses handling cytostatic drugs
    • Stucker I, Hirsch A, Doloy T, Bastie-Sigeac I, Hemon D. Urine mutagenicity, chromosomal abnormalities and sister chromatid exchanges in lymphocytes of nurses handling cytostatic drugs. Int Arch Occup Environ Health. 1986;57:195-205.
    • (1986) Int Arch Occup Environ Health , vol.57 , pp. 195-205
    • Stucker, I.1    Hirsch, A.2    Doloy, T.3    Bastie-Sigeac, I.4    Hemon, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.