Effect of Tsix disruption on Xist expression in male ES cells

Cytogenetic and Genome Research

Volumn 99, Issue 1-4, 2002, Pages 115-118

  Sado, T ^a,d   Li, E ^b,c   Sasaki, H ^a  

^a GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d NATIONAL INSTITUTE OF GENETICS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

RNA;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; EMBRYO; EMBRYO CELL; EMBRYO DEVELOPMENT; GENE ACTIVATION; GENE DISRUPTION; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL; X CHROMOSOME; X CHROMOSOME INACTIVATION;

ANIMALS; CELL LINE; EMBRYO; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MICE; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, UNTRANSLATED; STEM CELLS; TRANSCRIPTION FACTORS;

EID: 0344099527     PISSN: 14248581     EISSN: None     Source Type: Journal    
DOI: 10.1159/000071582     Document Type: Article

References (25)

1. Beard C, Li E, Jaenisch R: Loss of methylation activates Xist in somatic but not in embryonic cells. Genes Dev 9:2325-2334 (1995).
2. Borsani G, Tonlorenzi R, Simmler M. C, Dandolo L, Arnaud D, Capra V, Grompe M, Pizzuti A, Muzny D, Lawrence C, Willard HF, Avner P, Ballabio A: Characterization of a murine gene expressed from the inactive X chromosome. Nature 351:325-329 (1991).
3. Brockdorff N, Ashworth A, Kay GF, Cooper P, Smith S, McCabe VM, Norris DP, Penny GD, Patel D, Rastan S: Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome. Nature 351:329-331 (1991).
4. Brockdorff N, Ashworth A, Kay GF, McCabe VM, Norris DP, Cooper PJ, Swift S, Rastan S: the product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell 71:515-526 (1992).
5. Brown CJ, Ballabio A, Rupert JL, Lafreniere R, Grompe M, Tonlorenzi R, Willard HF: A gene from the region of the human X inactivation center is expressed exclusively from the inactive X chromosome. Nature 349:38-44 (1991).
6. Debrand E, Chureau C, Arnaud D. Avner P. Heard E: Functional analysis of the DXPas34 locus, a 3′ regulator of Xist expression. Mol Cell Biol 19:8513-8525 (1999).
7. Goto Y, Takagi N: Tetraploid embryos rescue embryonic lethality caused by an additional maternally inherited X chromosome in the mouse. Development 125:3353-3363 (1998).
8. Goto Y, Takagi N: Maternally inherited X chromosome is not inactivated in mouse blastocysts due to parental imprinting. Chrom Res 7:101-109 (2000).
9. Kay GF, Penny GD, Patel D, Ashworth A, Brockdorff N, Rastan S: Expression of Xist during mouse development suggests a role in the initiation X chromosome inactivation. Cell 72:171-182 (1993).
10. Lee JT: Disruption of imprinted X inactivation by parent-of-origin effects at Tsix. Cell 103:17-27 (2000).
11. Lee JT, Davidow LS, Warshawsky D: Tsix, a gene antisense to Xist at the X-inactivation centre. Nature Genet 21:400-404 (1999).
12. Lee JT, Lu N: Targeted mutagenesis of Tsix leads nonrandom X inactivation. Cell 99:47-57 (1999).
13. Li E, Bestor TH, Jaenisch R: Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69:915-926 (1992).
14. Luikenhuis S, Wutz A, Jaenisch R: Antisense transcription through the Xist locus mediates Tsix function in embryonic stem cells. Mol Cell Boil 21:8512-8520 (2001).
15. Lyon MF: Gene action in the X-chromosome of the mouse (Mus musculus L). Nature 190:372-373 (1961).
16. Marahrens Y, Panning B, Dausman J, Strauss W, Jaenisch R: Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev 11:156-166 (1997).
17. Martin GR, Epstein CJ, Travis B, Tucker G, Yatziv S, Martin Jr DW, Clift S, Cohen S: X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro. Nature 271:329 333 (1978).
18. Okamoto I, Tan S-S, Takagi N: X-chromosome inactivation in XX androgenetic mouse embryos surviving implantation. Development 127:4137-4145 (2000).
19. Panning B, Dausman J, Jaenisch R: X chromosome inactivation is mediated by Xist RNA stabilization. Cell 90:907-916 (1997).
20. Sado T, Tada T, Takagi N: Mosaic methylation of Xist gene before chromosome inactivation in undifferentiated female mouse embryonic stem and embryonic germ cells. Dev Dyn 205:421-434 (1996).
21. Sado T, Wang Z, Sasaki H, Li E: Regulation of imprinted X-chromosome inactivation in mice by Tsix. Development 128:1275-1286 (2001).
22. Shao C, Takagi N: An extra maternally derived X chromosome is deleterious to early mouse development. Development 110:969-975 (1990).
23. Sheardown SA, Duthie SM, Johnston CM, Newall AET, Formstone EJ, Arkell RM, Nesterova, TB, Alghisi G-C, Rastan S, Brockdorff N: Stabilization of Xist RNA mediates initiation of X chromosome inactivation. Cell 91:99-107 (1997).
24. Tada T, Obata Y, Tada M, Goto Y, Naktsuji N, Tan S-S, Kono T, Takagi N: Imprint switching for non-random X-chromosome inactivation during mouse oocyte growth. Development 127:3101-3105 (2000).
25. Wutz A, Jaenisch R: A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation. Mol Cell 5:695-705 (2000).