Evaluation of the anxiolytic-like effect of NKP608, a NK1-receptor antagonist, in two rat strains that differ in anxiety-related behaviors

Psychopharmacology

Volumn 170, Issue 3, 2003, Pages 287-293

  Vendruscolo, Leandro F ^a   Takahashi, Reinaldo N ^a   Brüske, Gustavo R ^a   Ramos, André ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Anxiety; Elevated plus maze; Lewis; NK 1 receptor antagonist; Open field; Spontaneously hypertensive rats

Indexed keywords

2 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 4 (3 OXO 1,2,4 TRIAZOL 5 YLMETHYL) 3 PHENYLMORPHOLINE; 3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; 3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 2 PHENYLPIPERIDINE; ANXIOLYTIC AGENT; APREPITANT; CHLORDIAZEPOXIDE; NEUROKININ 1 RECEPTOR ANTAGONIST; NKP 608; QUINOLINE 4 CARBOXYLIC ACID [1 (3,5 BISTRIFLUOROMETHYLBENZOYL) 2 (4 CHLOROBENZYL)PIPERIDIN 4 YL]AMIDE; SUBSTANCE P; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ANXIETY DISORDER; ARTICLE; CHROMOSOME 4; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; GENE DELETION; MAZE TEST; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RAT; RECEPTOR AFFINITY; RECEPTOR BLOCKING; SPONTANEOUSLY HYPERTENSIVE RAT; STRAIN DIFFERENCE; TRANQUILIZING ACTIVITY;

ANALYSIS OF VARIANCE; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; FEMALE; MALE; MAZE LEARNING; PIPERIDINES; QUINOLINES; RATS; RATS, INBRED LEW; RATS, INBRED SHR; RECEPTORS, NEUROKININ-1; SPECIES SPECIFICITY;

EID: 0344082220     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-003-1545-4     Document Type: Article

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