Presence of a pertussis toxin-sensitive G protein α subunit in Sporothrix schenckii

Medical Mycology

Volumn 38, Issue 2, 2000, Pages 109-121

  Delgado, N ^a   Rodríguez Del Valle, Nuri ^a  

^a UNIVERSITY OF PUERTO RICO   (Puerto Rico)

Author keywords

G proteins; Signal transduction; Sporothrix schenckii

Indexed keywords

FUNGAL DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; PERTUSSIS TOXIN;

ARTICLE; CELL MEMBRANE; FUNGUS; GENE AMPLIFICATION; GENE EXPRESSION; INTRON; NEUROSPORA CRASSA; NONHUMAN; NUCLEOTIDE SEQUENCE; PERTUSSIS; PHYLOGENY; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPOROTHRIX SCHENCKII;

CRYPHONECTRIA PARASITICA; FUNGI; MYXOGASTRIA; NEUROSPORA CRASSA; SPOROTHRIX SCHENCKII; TEREBRANTIA;

EID: 0343963079     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1080/714030929     Document Type: Article

References (56)

1. Travassos LR, Lloyd KO. Sporothrix schenckii and related species of Ceratocystis. Microbiol Rev 1980; 44: 683-721.
2. Betancourt S, Torres-Bauza LJ, Rodríguez-del Valle N. Molecular and cellular events during the yeast to mycelium transition in Sporothrix schenckii. Sabouraudia: J Med Vet Mycol 1985; 23: 207-218.
3. Resto S, Rodríguez-del Valle N. Yeast cell cycle of Sporothrix schenckii. J Med Vet Mycol 1988; 26: 13-24.
4. Rodríguez-del Valle N, Rosario M, Torres-Blasini G. Effects of pH, temperature, aeration, and carbon source on the development of the mycelial and yeast forms of Sporothrix schenckii. Mycopathologia 1983; 82: 83-88.
5. Alsina A, Rodríguez-del Valle N. Effects of divalent cations and functionally related substances on the yeast to mycelium transition in Sporothrix schenckii. Sabouraudia: J Med Vet Mycol 1984; 22: 1-5.
6. Rivera-Rodríguez N, Rodríguez-del Valle N. Effects of calcium ions on the germination of Sporothrix schenckii conidia. J Med Vet Mycol 1992; 30: 185-195.
7. Serrano S. Rodríguez-del Valle N. Calcium uptake and efflux during the yeast to mycelium transition in Sporothrix schenckii. Mycopathologia 1990; 112: 1-9.
8. Rodríguez-del Valle N, Rodríguez-Medina JR. Calcium stimulates molecular and cellular events during the yeast-to-mycelium transition in Sporothrix schenckii. J Med Vet Mycol 1993; 31: 43-53.
9. Rodríguez-del Valle N, Debs-Elías N, Alsina A. Effects of caffeine, cyclic 3′, 5′ adenosine monophosphate and cyclic 3′, 5′ guanosine monophosphate in the development of the mycelial form of Sporothrix schenckii. Mycopathologia 1984; 86: 29-33.
10. Colón-Colón W, Rodríguez-del Valle N. Studies on phase transitions in Sporothrix schenckii: Possible involvement of Protein Kinase C. In: Vanden Bossche H, Odds FC, Kerridge D, eds. Dimorphic Fungi in Biology and Medicine. New York: Plenum Publishing Co, 1993: 225-239.
11. Hamm HE, Gilchrist A. Heterotrimeric G proteins. Curr Opin Cell Biol 1996; 8: 189-196.
12. Kaziro Y, Itoh H, Kozasa T, Nakafuku M, Satoh T. Structure and function of signal-transducing GTP-binding proteins. Ann Rev Biochem 1991; 60: 349-400.
13. Sprang SR. G protein mechanisms: Insights from structural analysis. Anna Rev Biochem 1997; 66: 639-678.
14. Rens-Dimiano S, Hamm HE. Structural and functional relationships of heterotrimeric G-proteins. FASEB J 1995; 9: 1059-1066.
15. Wilkie TM, Yokoyama S. Evolution of the G protein alpha subunit multigene family. In: Molecular Evolution of Physiological Processes. New York: Rockefeller University Press, 1994: 249-270.
16. Baldwin JM. Structure and function of receptors coupled to G proteins. Curr Opin Cell Biol 1994; 6: 180-190.
17. 2+ channels with G-protein α and βγ subunits. J Biol Chem 1998; 273: 17595-17603.
18. 2+ channels by G-protein βγ subunits. Nature 1996; 380: 258-262.
19. iα. Science 1993; 261: 218-221.
20. Simon MI, Strathmann MP, Gautam N. Diversity of G proteins in signal transduction. Science 1991; 252: 802-808.
21. Buss JE, Mumby SM, Casey PJ, Gilman AG, Sefton BM. Myristoylated α subunits of guanine nucleotide-binding regulatory proteins. Proc Natl Acad Sci USA 1987; 84: 7493-7497.
22. iαl subunits by pertussis toxin. Biochemistry 1998; 37: 2748-2758.
23. West RE, Moss J, Vaughan M, Liu T, Liu TY. Pertussis toxin-catalyzed ADP-ribosylation of transducin. J Biol Chem 1985; 260: 14428-14430.
24. Stryer L. Cyclic GMP cascade of vision. Ann Rev Neurosci 1986; 9: 87-119.
25. Stoyanov B, Volinia S, Hanck T, et al. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science 1995; 269: 690-693.
26. Brown AM. Ionic channels and their regulation by G protein subunits. Ann Rev Physiol 1990; 52: 197-213.
27. αq expressed in rat taste buds. Biochim Biophys Acta 1998; 1403: 265-272.
28. Exton JH. Cell signaling through guanine-nucleotide-binding regulatory proteins (G proteins) and phospholipases. Eur J Biochem 1997; 243: 10-20.
29. α13 stimulates Na-H exchange. J Biol Chem 1994; 269: 4721-4724.
30. Nakafuku M, Itoh H, Nakamura S, Kaziro Y. Occurrence in Saccharomyces cerevisiae of a gene homologous to the cDNA coding for the α subunits of mammalian G proteins. Proc Natl Acad Sci USA 1987; 84: 2140-2144.
31. Nakafuku M, Obara T, Kaibuchi K, et al. Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions. Proc Natl Acad Sci USA 1988; 85: 1374-1378.
32. Sadhu C, Hekstra D, McEachern MJ, Reed SI, Hicks JB. A G protein α subunit from asexual Candida albicans functions in the mating signal-transduction pathway of Saccharomyces cerevisiae and is regulated by the aI-α2 repressor. Mol Cell Biol 1992; 12: 1977-1985.
33. Saviñón-Tejada AL, Ongay-Larios L, Ramírez J, Coria R. Isolation of a gene encoding a G protein α subunit involved in the regulation of cAMP levels in the yeast Kluyveromyces lactis. Yeast 1996; 12: 1125-1133.
34. Tolkacheva T, McNamara P, Piekarz E, Courchesne W. Cloning of a Cryptococcus neoformans gene, GPA1, encoding a G-protein α-subunit homolog. Infec Immun 1994; 62: 2849-2856.
35. Ma H, Yanofski MF, Meyerowitz EM. Molecular cloning and characterization of GPA1, a G protein α subunit gene from Arabidopsis thaliana. Proc Natl Acad Sci USA 1990; 87: 3821-3825.
36. Smulian AG, Ryan M, Staben C, Cushion MT. Signal transduction in Pneumocystis carinii: characterization of the genes (pcg1) encoding the alpha subunit of the G protein (PCG1) of Pneumocystis carinii carinii and Pneumocystis carinii ratti. Infect Immun 1996; 64: 691-701.
37. Alspaugh JA, Perfect JR, Heitman J. Cryptococcus neoformans mating and virulence are regulated by the G-protein α subunit GPA1 and cAMP. Genes Dev 1997; 11: 3206-3217.
38. i family. J Biol Chem 1993; 268: 14805-14811.
39. αi Homologue gna-1 controls multiple differentiation pathways in Neurospora crassa. Mol Biol Cell 1996: 7: 1283-1297.
40. Yu JH, Wieser J, Adams TH. The Aspergillus FlbA RGS domain protein antagonizes G protein signaling to block proliferation and allow development. EMBO J 1996; 15: 5184-5190.
41. Choi GH, Chen B, Nuss D. Virus-mediated or transgenic suppression of a G-protein α subunit and attenuation of fungal virulence. Proc Natl Acad Sci USA 1995; 92: 305-309.
42. Regenfelder E, Spellig T, Hartmann A, Lauenstein S, Bolker M, Kahmann R. G proteins in Ustilago maydis: transmission of multiple signals? EMBO J 1997; 16: 1934-1942.
43. Liu S, Dean RA. G protein α subunit genes control growth, development, and pathogenicity of Magnaporthe grisea. Mol Plant-Microb Interact 1997; 10: 1075-1086.
44. Mendonça L, Gorin PAJ, Lloyd KO, Travassos LR. Polymorphism of Sporothrix schenckii surface polysaccharides as a function of morphological differentiation. Biochemistry 1976; 15: 2423-2425.
45. Aquino-Piñero EE, Rodríguez-del Valle N. Different protein kinase C isoforms are present in the yeast and mycelium forms of Sporothrix schenckii. Mycopathologia 1997; 138: 109-115.
46. + -ATPases. Methods Enzymol 1988; 157: 562-571.
47. Laemmli UK. Cleavage of structural proteins during assembly of the bacteriophage T4. Nature 1970; 227: 680-685.
48. Carty DJ. Pertussis toxin-catalyzed ADP-ribosylation of G proteins. Methods Enzymol 1994; 237: 63-70.
49. Sherman F, Fink GR, Hicks JB. Methods in Yeast Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1986.
50. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159.
51. Wilkie TM, Aragay AM, Watson AJ, Simon MI. Design of degenerate oligonucleotide primers for cloning of G-protein α subunits. Methods Enzymol 1994; 237: 327-344.
52. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
53. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol 1990; 215: 403-410.
54. Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 1994; 22: 4673-4680.
55. Martinez-Cadena G, Novoa-Martinez G, Gonzalez-Hernandez A, Garcia-Soto J. The GTP-binding protein G alpha s is present in dormant spores and expressed differentially during spore germination of the fungus Phycomyces blakesleeanus. Microbiology 1995; 141: 3149-3154.
56. Raport CJ, Dere B, Hurley JB. Characterization of the mouse rod transducin α subunit gene. J Biol Chem 1989; 264: 7122-7128.