Mechanism of induction of cytochrome P450 enzymes by the proestrogenic endocrine disruptor pesticide-methoxychlor: Interactions of methoxychlor metabolites with the constitutive androstane receptor system

Drug Metabolism and Disposition

Volumn 29, Issue 6, 2001, Pages 781-785

  Kupfer, David ^a   Blizard, D ^b   Sueyoshi, T ^b   Negishi, M ^b   Dehal, S S ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANE DERIVATIVE; BENZENE DERIVATIVE; CHLORPHENOTANE; CYTOCHROME P450; DRUG METABOLITE; MESSENGER RNA; METHOXYCHLOR; PESTICIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG METABOLISM; DRUG POTENCY; DRUG STRUCTURE; ENZYME INDUCTION; ENZYME MECHANISM; ESTROGEN ACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; STRUCTURE ANALYSIS;

EID: 0343337185     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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