Characterization of parathyroid hormone/parathyroid hormone-related protein receptor and signaling in hypercalcemic Walker 256 tumor cells

Journal of Endocrinology

Volumn 166, Issue 1, 2000, Pages 11-20

  Esbrit, P ^a   Benitez Verguizas J ^a   De Miguel, F ^a,b   Valin A ^a   Garcia Ocana A ^a,b  

^a Bone and Mineral Metab Laboratory   (Spain)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RELATED PROTEIN; RNA;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL; CARCINOGENESIS; HORMONE DETERMINATION; HUMAN; HUMAN CELL; HYPERCALCEMIA; IMMUNOCYTOCHEMISTRY; MALIGNANT TRANSFORMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; RECEPTOR BINDING; RNA ANALYSIS; SIGNAL TRANSDUCTION; TUMOR MODEL; WALKER CARCINOMA;

EID: 0343193252     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1660011     Document Type: Article

References (37)

1. Abou-Samra A-B, Jüppner H, Force T, Freeman MW, Kong X-F, Schipani E, Ureña P, Richards J, Bonventre JV, Potts JT Jr, Kronenberg HM & Segre GV 1992 Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide for rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. PNAS 89 2732-2736.
2. Allgeier A, Offermanns S, van Sande J, Spicher K, Schultz G & Dumont JE 1994 The human thyrotropin receptor activates G-proteins Gs and Gq/11. Journal of Biological Chemistry 269 13733-13735.
3. Benítez-Verguizas J & Esbrit P 1994 Proliferative effect of parathyroid hormone-related protein on the hypercalcemic Walker 256 carcinoma cell line. Biochemical and Biophysical Research Communications 198 1281-1289.
4. Birch MA, Carron JA, Scott M, Fraser WD & Gallagher JA 1995 Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor expression and mitogenic responses in human breast cancer cell lines. British Journal of Cancer 72 90-95.
5. Blind E, Bambino T & Nissensson RA 1995 Agonist-stimulated phosphorylation of the G protein-coupled receptor for parathyroid hormone (PTH) and PTH-related protein. Endocrinology 136 4271-4277.
6. Carter PH, Shimizu M, Luck MD & Gardella TJ 1999 The hydrophobic residues phenylalanine 184 and leucine 187 in the type-1 parathyroid hormone (PTH) receptor functionally interact with the amino-terminal portion of PTH(1-34). Journal of Biological Chemistry 274 31955-31960.
7. Cataisson C, Lieberher M, de Vernejoul MC, Calvo F & Bouizar Z 1998 Expression of parathyroid hormone-related protein and PTH/PTHrP receptor signaling during malignant transformation of human breast cell lines. Bone 23 (Suppl) S445 (Abstract).
8. Gaich G, Orloff JJ, Atillasoy EJ, Burtis WJ, Ganz MB & Stewart AF 1993 Amino-terminal parathyroid hormone-related protein: specific binding and cytosolic calcium responses in rat insulinoma cells. Endocrinology 132 1402-1409.
9. García-Ocaña A, Gómez-Casero E, Peñaranda C., Sarasa JL & Esbrit P 1998 Cyclosporine increases renal parathyroid hormone-related protein expression in vivo in the rat. Transplantation 65 860-863.
10. Henderson JE, Kremer R, Rhim JS & Goltzman D 1992 Identification and functional characterization of adenylate cyclase-linked receptors for parathyroid hormone-like peptides on immortalized keratinocytes. Endocrinology 130 449-457.
11. Hunter WM & Greenwood FC 1962 Preparation of iodine-131-labelled human growth hormone of high specific activity. Nature 194 495-496.
12. Iida-Klein A, Guo J, Xie LY, Jüppner H, Potts JT Jr, Kronenberg HM, Bringhurst FR, Abou-Samra AB & Segre GV 1995 Truncation of the carboxyl-terminal region of the rat parathyroid hormone (PTH)/PTH-related peptide receptor enhances PTH stimulation of adenylyl cyclase but not phospholipase C. Journal of Biological Chemistry 270 8458-8465.
13. Jobert A-S, Fernandes I, Turner G, Coureau C, Prie D, Nissenson RA, Friedlander G & Silve C 1996 Expression of alternatively spliced isoforms of the parathyroid hormone (PTH)/PTH-related peptide receptor messenger RNA in human kidney and bone cells. Molecular Endocrinology 10 1066-1076.
14. Jüppner H, Abou-Samra A-B, Freeman M, Kong XF, Schipani E, Richards J, Kolakowski LF Jr, Hock J, Potts JT Jr, Kronenberg HM & Segre GV 1992 A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. Science 254 1024-1026.
15. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 680-685.
16. Largo R, Gómez-Garre D, Santos S, Peñaranda C, Blanco J, Esbrit P & Egido J 1999 Renal expression of parathyroid hormone-related protein (PTHrP) and PTH/PTHrP receptor in a rat model of tubulointerstitial damage. Kidney International 55 82-90.
17. Lee C, Gardella TJ, Abou-Samra A-B, Nussbaum SR, Segre GV, Potts JT Jr, Kronenberg HM & Jüppner H 1994 Role of the extracellular regions of the parathyroid hormone (PTH)/PTH-related peptide receptor in hormone binding. Endocrinology 135 1488-1495.
18. McCauley LK, Rosol TJ, Merryman JI & Capen CC 1992 Parathyroid hormone-related protein binding to human T-cell lymphotropic virus type I-infected lymphocytes. Endocrinology 130 300-306.
19. Maeda S, Wu S, Jüppner H, Green J, Aragay AM, Fagin JA & Clemens TL 1996 Cell-specific signal transduction of parathyroid hormone (PTH)-related protein through stably expressed recombinant PTH/PTHrP receptors in vascular smooth muscle cells. Endocrinology 137 3154-3162.
20. Martin KJ, McConkey ChJ Jr & Caulfield MP 1992 The role of protein kinase-A activity in the evaluation of agonist/antagonist properties of analogs of parathyroid hormone-related protein in opossum kidney cells. Endocrinology 131 2161-2164.
21. Martínez ME, García-Ocaña A, Sánchez M, Medina S, del Campo T, Valín A, Sánchez-Cabezudo MJ & Esbrit P 1997 C-terminal parathyroid hormone-related protein inhibits proliferation and differentiation of human osteoblast-like cells. Journal of Bone and Mineral Research 12 778-785.
22. Orloff JJ, Wu TL, Heath HW, Brady TG, Brines ML & Stewart AF 1989 Characterization of canine renal receptors for the parathyroid hormone-like protein associated with humoral hypercalcemia of malignancy. Journal of Biological Chemistry 264 6097-6103.
23. Orloff JJ, Ganz MB, Ribaudo AE, Burtis WJ, Reiss M, Milstone LM & Stewart AF 1992 Analysis of parathyroid hormone-related protein binding and signal transduction mechanisms in benign and malignant squamous cells. American Journal of Physiology 262 E599-E607.
24. Orloff JJ, Reddy D, De Papp AE, Yang KH & Soifer EN 1994 Parathyroid hormone-related protein as a prohormone: post-translational processing and receptor interactions. Endocrine Reviews 15 40-60.
25. Orloff JJ, Kats Y, Ureña P, Schipani E, Vasavada RC, Philbrick WM, Behal A, Abou-Samra A-B, Segre GV & Jüppner H 1995 Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines. Endocrinology 136 3016-3023.
26. Philbrick WM, Wysolmerski JJ, Galbraith S, Holt E, Orloff JJ, Yang KH, Vasavada RC, Weir EC, Broadus AE & Stewart AF 1996 Defining the roles of parathyroid hormone-related protein in normal physiology. Physiological Reviews 76 127-173.
27. Schipani E, Karga H, Karaplis AC, Potts JT Jr, Kronenberg HM, Segre GV, Abou-Samra A-B & Jüppner H 1993 Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor. Endocrinology 132 2157-2165.
28. Schneider H, Feyen JHM & Seuwen K 1994 A C-terminally truncated human parathyroid hormone receptor is functional and activates multiple G proteins. FEBS Letters 351 281-285.
29. Seitz PK, Cooper KM, Ives KL, Ishizuka J, Townsend CM Jr, Rajaraman S & Cooper CW 1993 Parathyroid hormone-related peptide production and action in a myoepithelial cell line derived from normal human breast. Endocrinology 133 1116-1124.
30. Simon MI, Strathmann MP & Gautam N 1991 Diversity of G proteins in signal transduction. Science 252 802-808.
31. Simpkins H, Lehman JM, Mazurkiewicz JE & Davis BH 1991 A morphological and phenotypic analysis of Walker 256 cells. Cancer Research 51 1334-1338.
32. Takasu H & Bringhurst FR 1998 Type-1 parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptors activate phospholipase C in response to carboxyl-truncated analogs of PTH(1-34). Endocrinology 139 4293-4299.
33. Takasu H, Guo J & Bringhurst FR 1999 Dual signaling and ligand selectivity of the PTH/PTHrP receptor. Journal of Bone and Mineral Research 14 11-20.
34. 1 vascular vasopressin receptors. American Journal of Physiology 264 C1336-C1344.
35. Valín A, García-Ocaña A, de Miguel F, Sarasa JL & Esbrit P 1997 Antiproliferative effect of the C-terminal fragments of parathyroid hormone related protein, PTHrP-(107-111) and -(107-139), on osteoblastic osteosarcoma cells. Journal of Cellular Physiology 170 209-215.
36. Villanueva-Peñacarrillo ML, Cancelas J, de Miguel F, Redondo A, Valín A, Valverde I & Esbrit P 1999 Parathyroid hormone-related peptide stimulates DNA synthesis and insulin secretion in pancreatic islets. Journal of Endocrinology 163 403-408.
37. Yaghoobian J, Morieux C, Denne MA, Bouizar Z, Ureña P & de Vernejoul MC 1998 Pamidronate corrects the down-regulation of the renal parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor mRNA in rats bearing Walker tumors. Hormone and Metabolic Research 30 249-255.