Spatial mapping of T2 and gadolinium-enhancing T1 lesion volumes in multiple sclerosis: Evidence for distinct mechanisms of lesion genesis?

Brain

Volumn 122, Issue 7, 1999, Pages 1261-1270

  Lee, M A ^a,b   Smith, S ^a   Palace, J ^b   Narayanan, S ^d   Silver, N ^c   Minicucci, L ^e   Filippi, M ^e   Miller, D H ^c   Arnold, D L ^d   Matthews, P M ^a,b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b RADCLIFFE INFIRMARY   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

Inflammation; MRI; Multiple sclerosis; Neuropathology; Plaque

Indexed keywords

CONTRAST MEDIUM; GADOLINIUM;

ADULT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INJURY; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; FEMALE; HUMAN; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; PRIORITY JOURNAL; WHITE MATTER;

EID: 0032764919     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/122.7.1261     Document Type: Article

References (31)

1. Adams CW, Poston RN, Buk SJ, Sidhu YS, Vipond H. Inflammatory vasculitis in multiple sclerosis. J Neurol Sci 1985; 69: 269-83.
2. Barkhof F, Filippi M. Can MRI be a predictor of long-term clinical outcome for MS? Int MS J 1995; 2: 4-9.
3. Bastianello S, Pozzilli C, Bernardi S, Bozzao L, Fantozzi LM, Buttinelli C, et al. Serial study of gadolinium-DTPA MRI enhancement in multiple sclerosis. Neurology 1990; 40: 591-5.
4. Bastianello S, Bozzao A, Paolillo A, Giugni E, Gasperini C, Koudriavtseva T, et al. Fast spin-echo and fast fluid-attenuated inversion-recovery versus conventional spin-echo sequences for MR quantification of multiple sclerosis lesions. AJNR Am J Neuroradiol 1997; 18: 699-704.
5. Collins DL, Neelin P, Peters TM, Evans AC. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 1994; 18: 192-205.
6. Evans AC, Collins DL, Mills SR, Brown ED, Kelly RL, Peters TM. 3D statistical neuroanatomical models from 305 MRI volumes. Proceedings IEEE Nuclear Science Symposium and Medical Imaging Conference; 1993. p. 1813-7.
7. Filippi M, Paty DW, Kappos L, Barkhof F, Compston DA, Thompson AJ, et al. Correlations between changes in disability and T2- weighted brain activity in multiple sclerosis: a follow-up study. Neurology 1995a; 45: 255-60.
8. Filippi M, Horsfield MA, Campi A, Mammi S, Pereira C, Comi G. Resolution-dependent estimates of lesion volumes in magnetic resonance imaging studies of the brain in multiple sclerosis. Ann Neurol 1995b; 38: 749-54.
9. Filippi M, Yousry T, Baratti C, Horsfield MA, Mammi S, Becker C, et al. Quantitative assessment of MRI lesion load in multiple sclerosis. A comparison of conventional spin-echo with fast fluid-attenuated inversion recovery. Brain 1996; 119: 1349-55.
10. Filippi M, Rovaris M, Capra R Gasperini C, Yousry TA, Sormani MP, et al. A multi-centre longitudinal study comparing the sensitivity of monthly MRI after standard and triple dose gadolinium-DTPA for monitoring disease activity in multiple sclerosis. Implications for phase II clinical trials. Brain 1998; 121: 2011-20.
11. Friston KJ, Ashburner J, Frith CD, Poline JB, Heather JD, Frackowiak RSJ. Spatial registration and normalization of images. Hum Brain Mapp 1995; 2: 165-89.
12. Gay FW, Drye TJ, Dick GW, Esiri MM. The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion. Brain 1997; 120: 1461-83.
13. Hawkins CP, Munro PM, MacKenzie F, Kesselring J, Tofts PS, du Boulay EP, et al. Duration and selectivity of blood-brain barrier breakdown in chronic relapsing experimental allergic encephalomyelitis studied by gadolinium-DTPA and protein markers. Brain 1990; 113: 365-78.
14. Katz J, Taubenberger J, Raine C, McFarlin D, McFarland H. Gadolinium-enhancing lesions on magnetic resonance imaging: neuropathological findings [abstract]. Ann Neurol 1990; 28: 243.
15. Kermode AG, Tofts PS, Thompson AJ, MacManus DG, Rudge P, Kendall BE, et al. Heterogeneity of blood-brain barrier changes in multiple sclerosis: an MRI study with gadolinium-DTPA enhancement. Neurology 1990; 40: 229-35.
16. Koudriavtseva T, Thompson AJ, Fiorelli M, Gasperini C, Bastianello S, Bozzao A, et al. Gadolinium enhanced MRI predicts clinical and MRI disease activity in relapsing-remitting multiple sclerosis. J Neurol Neurosurg Psychiatry 1997; 62: 285-7.
17. Kuharik MA, Edwards MK, Farlow MR, Becker GJ, Azzarelli B, Klatte EC, et al. Gadolinium-enhanced MR imaging of acute and chronic experimental demyelinating lesions. AJNR Am J Neuroradiol 1988; 9: 643-8.
18. Lai M, Hodgson T, Gawne-Cain M, Webb S, MacManus D, McDonald WI, et al. A preliminary study into the sensitivity of disease activity detection by serial weekly magnetic resonance imaging in multiple sclerosis. J Neurol Neurosurg Psychiatry 1996; 60: 339-41.
19. 2-weighted difference imaging. Brain 1998; 121: 2095-102.
20. Miller DH. Magnetic resonance in monitoring the treatment of multiple sclerosis. [Review]. Ann Neurol 1994; 36 Suppl: S91-4.
21. Miller DH, Rudge P, Johnson G, Kendall BE, MacManus DG, Moseley IF, et al. Serial gadolinium enhanced magnetic resonance imaging in multiple sclerosis. Brain 1988; 111: 927-39.
22. Miller DH, Barkhof F., Nauta JJ. Gadolinium enhancement increases the sensitivity of MRI in detecting disease activity in multiple sclerosis. Brain 1993; 116: 1077-94.
23. Miyai I, Blau AD, Reding MJ, Volpe BT. Patients with stroke confined to basal ganglia have diminished response to rehabilitation efforts. Neurology 1997; 48: 95-101.
24. Narayana PA, Doyle TJ, Lai D, Wolinsky JS. Serial proton magnetic resonance spectroscopic imaging, contrast-enhanced magnetic resonance imaging, and quantitative lesion volumetry in multiple sclerosis. Ann Neurol 1998; 43: 56-71.
25. Narayanan S, Fu L, Pioro E, De Stefano N, Collins DL, Francis GS, et al. Imaging of axonal damage in multiple sclerosis: spatial distribution of magnetic resonance imaging lesions. Ann Neurol 1997; 41: 385-91.
26. Penhune VB, Zatorre RJ, MacDonald JD, Evans AC. Interhemispheric anatomical differences in human primary auditory cortex: probabilistic mapping and volume measurement from magnetic resonance scans. Cereb Cortex 1996; 6: 661-72.
27. Talairach J, Tournoux P. Co-planar stereotaxic atlas of the human brain: 3-dimensional proportional system: an approach to cerebral imaging. Stuttgart: Thieme; 1988.
28. Thompson AJ, Kermode AG, Wicks D, MacManus DG, Kendall BE, Kingsley DP, et al. Major differences in the dynamics of primary and secondary progressive multiple sclerosis. Ann Neurol 1991; 29: 53-62.
29. Thompson AJ, Miller D, Youl B, MacManus D, Moore S, Kingsley D, et al. Serial gadolinium-enhanced MRI in relapsing/remitting multiple sclerosis of varying disease duration. Neurology 1992; 42: 60-3.
30. Wong JCH, Studholme C, Hawkes DJ, Maisey MN. Evaluation of the limits of visual detection of image misregistration in a brain fluorine-18 fluorodeoxyglucose PET-MRI study. Eur J Nucl Med 1997; 24: 642-50.
31. Yousry TA, Filippi M, Becker C, Horsfield MA, Voltz R. Comparison of MR pulse sequences in the detection of multiple sclerosis lesions. AJNR Am J Neuroradiol 1997; 18: 959-63.