Effects of theophylline and ipratropium bromide on exercise performance in patients with stable chronic obstructive pulmonary disease

Thorax

Volumn 53, Issue 4, 1998, Pages 269-273

  Tsukino, Mitsuhiro ^a   Nishimura, Koichi ^a   Ikeda, Akihiko ^a   Hajiro, Takashi ^a   Koyama, Hiroshi ^a   Izumi, Takateru ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Chronic obstructive pulmonary disease; Exercise capacity; Ipratropium bromide; Theophylline

Indexed keywords

CHOLINERGIC RECEPTOR BLOCKING AGENT; IPRATROPIUM BROMIDE; PLACEBO; THEOPHYLLINE;

ARTICLE; BICYCLE ERGOMETRY; BLOOD PRESSURE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DYSPNEA; EXERCISE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; LUNG MINUTE VOLUME; MALE; PRIORITY JOURNAL; PULSE RATE; RANDOMIZED CONTROLLED TRIAL; SPIROMETRY;

EID: 0031924890     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.53.4.269     Document Type: Article

References (18)

1. Siafakas NM, Vermeire P, Pride NB, et al. European Respiratory Society. Optimal assessment and management of chronic obstructive pulmonary disease. Eur Respir J 1995;8:1389-420.
2. Celli BR, Snider GL, Heffner J, et al. American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1995;152:S77-S120.
3. Eaton ML, MacDonald FM, Church TR, et al. Effects of theophylline on breathlessness and exercise tolerance in patients with chronic airflow obstruction, Chest 1982;82: 538-42.
4. Marvin PM, Baker BJ, Dutt AK, et al. Physiologic effects of oral bronchodilators during rest and exercise in chronic obstructive pulmonary disease. Chest 1983;84:684-9.
5. Guyatt GH, Townsend M, Pugsley SO, et al. Bronchodilators in chronic airflow limitation. Am Rev Respir Dis 1987; 135:1069-74.
6. Chrystyn H, Mulley BA, Peake MD. Dose response relation to oral theophylline in severe chronic obstructive airways disease. BMJ 1988;297:1506-10.
7. McKay SE, Howie CA, Thomson AH, et al. Value of theophylline treatment in patients handicapped by chronic obstructive lung disease. Thorax 1993;48:227-32.
8. Fink G, Kaye C, Sulkes J, et al. Effects of theophylline on exercise performance in patients with severe chronic obstructive pulmonary disease. Thorax 1994;49:332-4.
9. Mahler DA, Matthay RA, Snyder PE, et al. Sustained-release theophylline reduces dyspnea in nonreversible obstructive airway disease. Am Rev Respir Dis 1985;131:22 5.
10. Medical Section of the American Lung Association. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Med 1987;136:225-44.
11. Ikeda A, Nishimura K, Koyama H, et al. Dose response study of ipratropium bromide aerosol on maximum exercise performance in stable patients with chronic obstructive pulmonary disease. Thorax 1996;51:48-53.
12. Borg GAV. Psychophysical bases of perceived exertion. Med Sci Sports. Exerc 1982;14:377-81.
13. Carter R, Peavler M, Zinkgraf S, et al. Predicting maximal exercise ventilation in patients with chronic obstructive pulmonary disease. Chest 1987;92:253-9.
14. Jones NL, Campbell EJM. Clinical exercise testing. 2nd ed. Philadelphia: WB Saunders, 1982: 119.
15. Vozeh S, Kewitz G, Perruchoud A, et al. Theophylline serum concentration and therapeutic effect in severe acute bronchial obstruction: the optimal use of intravenously administered aminophylline. Am Rev Respir Dis 1982;125: 181 4.
16. Killian KJ, Leblanc P, Martin DH, et al. Exercise capacity and ventilatory, circulatory, and symptom limitation in patients with chronic airflow limitation. Am Rev Respir Dis 1992;146:935-40.
17. Murciano D, Anclair MH, Pariente R, et al. A randomized, controlled trial of theophylline in patients with severe chronic obstructive pulmonary disease. N Engl J Med 1989;320:1521-5.
18. Teramoto S, Fukuchi Y, Orimo H. Effects of inhaled anticholinergic drug on dyspnea and gas exchange during exercise in patients with chronic obstructive pulmonary disease. Chest 1993;103:1774-82.