How does your virus grow? Understanding and interfering with virus assembly

Trends in Biotechnology

Volumn 21, Issue 12, 2003, Pages 536-542

  Zlotnick, Adam ^a   Stray, Stephen J ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG THERAPY; GENES; PROTEINS;

ICOSAHEDRAL CAPSIDS;

VIRUSES;

CAPSID PROTEIN; DIMER; VIRUS DNA; VIRUS PROTEIN; VIRUS RNA;

VIRUS;

BROMOVIRUS; CARBOXY TERMINAL SEQUENCE; HEPATITIS B VIRUS; HERPES SIMPLEX VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; INSECT VIRUS; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; NONHUMAN; PICORNAVIRUS; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; RETROVIRUS; REVIEW; RHINOVIRUS; RNA BINDING; THERMODYNAMICS; VIROGENESIS; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS GENOME;

BROMOVIRUS; DNA VIRUSES; HEPATITIS B VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; INSECTA; PICORNAVIRIDAE; POLIOVIRUS; RHINOVIRUS; RNA VIRUSES; SIMPLEXVIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0242643745     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibtech.2003.09.012     Document Type: Review

References (69)

1. Endy D., Yin J. Toward antiviral strategies that resist viral escape. Antimicrob. Agents Chemother. 44:2000;1097-1099.
2. Rossmann M.G. Constraints on the assembly of spherical virus particles. Virology. 134:1984;1-11.
3. Prevelige P.E. Inhibiting virus-capsid assembly by altering the polymerisation pathway. Trends Biotechnol. 16:1998;61-65.
4. Salunke D., et al. Polymorphism in the assembly of polyomavirus capsid protein VP1. Biophys. J. 56:1989;887-900.
5. Johnson J.E. Functional implications of protein-protein interactions in icosahedral viruses. Proc. Natl. Acad. Sci. U. S. A. 93:1996;27-33.
6. Zlotnick A., et al. A small molecule inhibits and misdirects assembly of hepatitis B virus capsids. J. Virol. 76:2002;4844-4848.
7. Deres K., et al. Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids. Science. 299:2003;893-896.
8. Tang C., et al. Antiviral inhibition of the HIV-1 capsid protein. J. Mol. Biol. 327:2003;1013-1020.
9. Smith T.J., Baker T. Picornaviruses: epitopes, canyons, and pockets. Adv. Virus Res. 52:1999;1-23.
10. Hadfield A.T., et al. Analysis of three structurally related antiviral compounds in complex with human rhinovirus 16. Proc. Natl. Acad. Sci. U. S. A. 96:1999;14730-14735.
11. Tsang S.K., et al. Kinetic analysis of the effect of poliovirus receptor on viral uncoating: the receptor as a catalyst. J. Virol. 75:2001;4984-4989.
12. Phelps D.K., et al. Influence of an antiviral compound on the temperature dependence of viral protein flexibility and packing: a molecular dynamics study. J. Mol. Biol. 276:1998;331-337.
13. Phelps D.K., Post C.B. Molecular dynamics investigation of the effect of an antiviral compound on human rhinovirus. Protein Sci. 8:1999;2281-2289.
14. Speelman B., et al. Molecular dynamics simulations of human rhinovirus and an antiviral compound. Biophys. J. 80:2001;121-129.
15. Lee W.M., Wang W. Human rhinovirus type 16: mutant V1210A requires capsid-binding drug for assembly of pentamers to form virions during morphogenesis. J. Virol. 77:2003;6235-6244.
16. Khor I.W., et al. Novel strategy for inhibiting viral entry by use of a cellular receptor-plant virus chimera. J. Virol. 76:2002;4412-4419.
17. Zlotnick A. To build a virus capsid. An equilibrium model of the self assembly of polyhedral protein complexes. J. Mol. Biol. 241:1994;59-67.
18. Endres D., Zlotnick A. Model-based analysis of assembly kinetics for virus capsids or other spherical polymers. Biophys. J. 83:2002;1217-1230.
19. Bruinsma R.F., et al. Viral self-assembly as a thermodynamic process. Phys. Rev. Lett. 90:2003;248101.
20. Berger B., et al. Local rule-based theory of virus shell assembly. Proc. Natl. Acad. Sci. U. S. A. 91:1994;7732-7736.
21. Schwartz R., et al. Local rules simulation of the kinetics of virus capsid self-assembly. Biophys. J. 75:1998;2626-2636.
22. Rapaport D.C., et al. Supramolecular self-assembly: molecular dynamics modeling of polyhedral shell formation. Comp. Phys. Comm. 121:1999;231-235.
23. Ceres P., Zlotnick A. Weak protein-protein interactions are sufficient to drive assembly of hepatitis B virus capsids. Biochemistry. 41:2002;11525-11531.
24. Reddy V.S., et al. Energetics of quasiequivalence: computational analysis of protein-protein interactions in icosahedral viruses. Biophys. J. 74:1998;546-558.
25. Singh S., Zlotnick A. Observed hysteresis of virus capsid disassembly is implicit in kinetic models of assembly. J. Biol. Chem. 278:2003;18249-18255.
26. Zlotnick A., et al. A theoretical model successfully identifies features of hepatitis B virus capsid assembly. Biochemistry. 38:1999;14644-14652.
27. Zlotnick A., et al. Mechanism of capsid assembly for an icosahedral plant virus. Virology. 277:2000;450-456.
28. Bancroft J.B. The self-assembly of spherical plant viruses. Adv. Virus Res. 16:1970;99-134.
29. Adolph K.W., Butler P.J.G. Reassembly of a spherical virus in mild conditions. Nature. 255:1975;737-738.
30. Prevelige P.E., et al. Nucleation and growth phases in the polymerization of coat and scaffolding subunits into icosahedral procapsid shells. Biophys. J. 64:1993;824-835.
31. Zlotnick A., et al. Dimorphism of hepatitis B virus capsids is strongly influenced by the C-terminus of the capsid protein. Biochemistry. 35:1996;7412-7421.
32. Wynne S.A., et al. The crystal structure of the human hepatitis B virus capsid. Mol. Cell. 3:1999;771-780.
33. Silva J.L., Weber G. Pressure-induced dissociation of brome mosaic virus. J. Mol. Biol. 199:1988;149-159.
34. Da Poian A.T., et al. Reversible pressure dissociation of R17 bacteriophage. The physical individuality of virus particles. J. Mol. Biol. 231:1993;999-1008.
35. Li Q., et al. Poliovirus neutralization by antibodies to internal epitopes of VP4 and VP1 results from reversible exposure of these sequences at physiological temperature. J. Virol. 68:1994;3965-3970.
36. Pumpens P., et al. Hepatitis B virus core particles as epitope carriers. Intervirology. 38:1995;63-74.
37. Bothner B., et al. Evidence of viral capsid dynamics using limited proteolysis and mass spectrometry. J. Biol. Chem. 273:1998;673-676.
38. Bothner B., et al. Crystallographically identical virus capsids display different properties in solution. Nat. Struct. Biol. 6:1999;114-116.
39. Lewis J.K., et al. Antiviral agent blocks breathing of the common cold virus. Proc. Natl. Acad. Sci. U. S. A. 95:1998;6774-6778.
40. Douglas T., Young M. Host-guest encapsulation of materials by assembled virus protein cages. Nature. 393:1998;152-155.
41. Speir J.A., et al. Structures of the native and swollen forms of cowpea chlorotic mottle virus determined by X-ray crystallography and cryo-electron microscopy. Structure. 3:1995;63-78.
42. Lucas R.W., et al. The crystallographic structure of brome mosaic virus. J. Mol. Biol. 317:2002;95-108.
43. Smith T.J., et al. The structure of cucumber mosaic virus and comparison to cowpea chlorotic mottle virus. J. Virol. 74:2000;7578-7586.
44. Rossmann M.G., Johnson J.E. Icosahedral RNA virus structure. Annu. Rev. Biochem. 58:1989;533-573.
45. Krol M.A., et al. RNA-controlled polymorphism in the in vivo assembly of 180-subunit and 120-subunit virions from a single capsid protein. Proc. Natl. Acad. Sci. U. S. A. 96:1999;13650-13655.
46. Willits D., et al. Effects of the cowpea chlorotic mottle bromovirus β-hexamer structure on virion assembly. Virology. 306:2003;280-288.
47. Lucas R.W., et al. Crystallization of brome mosaic virus and T=1 brome mosaic virus particles following a structural transition. Virology. 286:2001;290-303.
48. Erickson J.W., et al. The structure of a T=1 icosahedral empty particle from southern bean mosaic virus. Science. 229:1985;625-629.
49. Lokesh G.L., et al. A molecular switch in the capsid protein controls the particle polymorphism in an icosahedral virus. Virology. 292:2002;211-223.
50. Lowy D.R., Schiller J.T. Papillomaviruses: prophylactic vaccine prospects. Biochim. Biophys. Acta. 1423:1999;M1-M8.
51. Koutsky L.A., et al. A controlled trial of a human papillomavirus type 16 vaccine. N. Engl. J. Med. 347:2002;1645-1651.
52. Chromy L.R., et al. Chaperone-mediated in vitro assembly of polyomavirus capsids. Proc. Natl. Acad. Sci. U. S. A. 100:2003;10477-10482.
53. Ganser B.K., et al. Assembly and analysis of conical models for the HIV-1 core. Science. 283:1999;80-83.
54. Lanman J., et al. Kinetic analysis of the role of intersubunit interactions in human immunodeficiency virus type 1 capsid protein assembly in vitro. J. Virol. 76:2002;6900-6908.
55. Prevelige P.E. Jr, et al. Pressure denaturation of the bacteriophage P22 coat protein and its entropic stabilization in icosahedral shells. Biophys. J. 66:1994;1631-1641.
56. Capen C.M., Teschke C.M. Folding defects caused by single amino acid substitutions in a subunit are not alleviated by assembly. Biochemistry. 39:2000;1142-1151.
57. Thuman-Commike P.A., et al. Mechanism of scaffolding-directed virus assembly suggested by comparison of scaffolding-containing and scaffolding-lacking P22 procapsids. Biophys. J. 76:1999;3267-3277.
58. Bernal R.A., et al. Structural studies of bacteriophage α3 assembly. J. Mol. Biol. 325:2003;11-24.
59. Newcomb W.W., et al. Assembly of the herpes simplex virus procapsid from purified components and identification of small complexes containing the major capsid and scaffolding proteins. J. Virol. 73:1999;4239-4250.
60. Heymann J.B., et al. Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy. Nat. Struct. Biol. 10:2003;334-341.
61. Conway J.F., et al. Virus maturation involving large subunit rotations and local re-folding. Science. 292:2001;744-748.
62. Hendrix R.W., Duda R.L. Bacteriophage HK97 head assembly: a protein ballet. Adv. Virus Res. 50:1998;235-288.
63. Galisteo M.L., King J. Conformational transformations in the protein lattice of phage P22 procapsids. Biophys. J. 65:1993;227-235.
64. Schneemann A., et al. Maturation cleavage required for infectivity of a nodavirus. J. Virol. 66:1992;6728-6734.
65. Schneemann A., et al. The structure and function of nodavirus particles: a paradigm for understanding chemical biology. Adv. Virus Res. 50:1998;381-446.
66. Krishna N.K., et al. Analysis of RNA packaging in wild-type and mosaic protein capsids of flock house virus using recombinant baculovirus vectors. Virology. 305:2003;10-24.
67. Taylor D.J., et al. Large-scale, pH-dependent, quaternary structure changes in an RNA virus capsid are reversible in the absence of subunit autoproteolysis. J. Virol. 76:2002;9972-9980.
68. Caspar D.L.D., Klug A. Physical principles in the construction of regular viruses. Cold Spring Harb. Symp. Quant. Biol. 27:1962;1-24.
69. Fuller S.D., et al. Cryo-electron microscopy reveals ordered domains in the immature HIV-1 particle. Curr. Biol. 7:1997;729-738.