Exposure to Asphalt Fumes Activates Activator Protein-1 through the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway in Mouse Epidermal Cells

Journal of Biological Chemistry

Volumn 278, Issue 45, 2003, Pages 44265-44272

  Ma, Cuiling ^a,b   Wang, Jin ^c   Luo, Jia ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPHALT; CELLS; CHEMICAL ACTIVATION; SKIN; TUMORS;

CARCINOGENESIS;

ENZYMES;

2 MORPHOLINO 8 PHENYLCHROMONE; 4 BENZYL 2 METHYL 1,2,4 THIADIAZOLIDINE 3,5 DIONE; AGAR; ASPHALT; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR; GLYCOGEN SYNTHASE KINASE 3BETA; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE; SERINE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; THREONINE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; WORTMANNIN;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL CELL; CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVATION; EPIDERMIS CELL; EVIDENCE BASED MEDICINE; FEMALE; FUME; KERATINOCYTE; MALE; MOUSE; NEWBORN; NONHUMAN; OCCUPATIONAL EXPOSURE; PAINTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPORTER GENE; SIGNAL TRANSDUCTION; SIMULATION; SKIN; SKIN CARCINOGENESIS; STATISTICAL SIGNIFICANCE; STIMULATION; TAIL; TRANSGENIC MOUSE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; ENZYME ACTIVATION; EPIDERMIS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENE EXPRESSION; HYDROCARBONS; KERATINOCYTES; LUCIFERASES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SKIN; SKIN NEOPLASMS; TRANSCRIPTION FACTOR AP-1;

ANIMALIA; MUS MUSCULUS; VERTEBRATA;

EID: 0242582452     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309023200     Document Type: Article

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