A healthy understanding of intraflagellar transport

Cell Motility and the Cytoskeleton

Volumn 52, Issue 1, 2002, Pages 1-8

  Sloboda, Roger D ^a  

^a Dartmouth College   (United States)

Author keywords

C. elegans; Human health and disease; Intraflagellar transport (IFT)

Indexed keywords

CELL PROTEIN;

CAENORHABDITIS ELEGANS; CELL FUNCTION; CELL MOTILITY; CHEMORECEPTOR; CHLAMYDOMONAS; EUKARYOTIC FLAGELLUM; FLAGELLUM; HUMAN; INTRAFLAGELLAR TRANSPORT; KIDNEY POLYCYSTIC DISEASE; MATING; MICROTUBULE; NONHUMAN; OSMOSIS; PHOTORECEPTOR; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; BIOLOGICAL TRANSPORT; CAENORHABDITIS ELEGANS; CELL MEMBRANE; CHLAMYDOMONAS; CILIA; FLAGELLA; MUTATION; OSMOSIS; POLYCYSTIC KIDNEY DISEASES; SEXUAL BEHAVIOR, ANIMAL; SIGNAL TRANSDUCTION;

CHLAMYDOMONAS;

EID: 0036250552     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/cm.10035     Document Type: Short Survey

References (41)

1. A human syndrome caused by immotile cilia
2. The immotile-cilia syndrome: A microtubule-associated defect
3. The Caenorhabditis elegans autosomal dominant polycysfic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway
4. Functions of lipid rafts in biological membranes
5. Rotokinesis, a novel phenomenon of cell locomotion-assisted cytokinesis in the ciliate Tetrahymena thermophila
6. Cilia propel the embryo in the right direction
7. Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons
8. Analysis of osm-6, a gene that affects sensory cilium structure and sensory neuron function in Caenorhabditis elegans
9. A novel WD40 protein, CHE-2, acts cell-autonomously in the formation of C. elegans sensory cilia
10. The C. elegans homolog of the murine cystic kidney disease gene Tg737 functions in a ciliogenic pathway and is disrupted in osm-5 mutant worms
11. Protein particles in Chlamydomonas flagella undergo a transport cycle consisting of four phases
12. A motility in the eukaryotic flagellum unrelated to flagellar beating
13. The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane
14. Explorations in cell motility
15. Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors
16. Chlamydomonas IFT172 is homologous to the rat selective LIM domain-binding (SLB) protein, a transcription factor-binding protein
17. Candidate gene associated with a mutation causing severe recessive polycystic kidney disease in mice
18. The Oak Ridge polycystic kidney (orpk) disease gene is required for left-right axis determination
19. Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor
20. Abnormal nodal flow precedes situs inversus in iv and inv mice
21. A dynein light chain is essential for retrograde particle movement in intraflagellar transport (IFT)
22. The DHClb (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly
23. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella
24. Intraflagellar transport is essential for vertebrate photoreceptor development
25. Mutant sensory cilia in the nematode Caenorhabditis elegans
26. Distinct mutants of retrograde intraflagellar transport (IFT) share similar morphological and molecular defects
27. Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas
28. Bending the MDCK cell primary cilium increases intracellular calcium
29. An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons
30. Flexible substrate technique for viewing cells from the side: Some in vivo properties of primary (9+0) cilia in cultured kidney epithelia
31. Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegans
32. Two heteromeric kinesin complexes in chemosensory neurons and sensory cilia of Caenorhabditis elegans
33. Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries
34. Molecular motors: The driving force behind mammalian left-right development
35. Substrate-cytoskeletal coupling as a mechanism for the regulation of growth cone motility and guidance
36. -/- mice analysis
37. Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia
38. Microtubule polarity and distribution in teleost photoreceptors
39. The Chlamydomonas FLA1O gene encodes a novel kinesin-homologous protein
40. Molecular cloning of a novel protein regulated by opioid tratment of NG108-15 cells
41. CHE-3, a cytosolic dynein heavy chain, is required for sensory cilia structure and function in Caenorhabditis elegans