Human calcium-sensing receptor can be suppressed by antisense sequences

Biochemical and Biophysical Research Communications

Volumn 311, Issue 3, 2003, Pages 610-617

  Maldonado Pérez, David ^a   Breitwieser, Gerda E ^b   Gama, Lucio ^c   Elliott, Austin C ^a   Ward, Donald T ^a   Riccardi, Daniela ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b SYRACUSE UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM SENSING RECEPTOR; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR CALCIUM SENSING RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CALCIUM CELL LEVEL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA SEQUENCE; EMBRYO; EXTRACELLULAR CALCIUM; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; KIDNEY CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

EID: 0242577586     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.10.041     Document Type: Article

References (30)

1. 2+ and other ions as extracellular (first) messengers. Physiol. Rev. 71:1991;371-411.
2. 2+-sensing receptor from bovine parathyroid. Nature. 366:1993;575-580.
3. Brown E.M., MacLeod R.J. Extracellular calcium sensing and extracellular calcium signalling. Physiol. Rev. 81:2001;239-297.
4. 2+-sensing receptor. Proc. Natl. Acad. Sci. USA. 97:2000;4814-4819.
5. Nemeth E.F. Pharmacological regulation of parathyroid hormone secretion. Curr. Pharm. Des. 8:2002;2077-2087.
6. Kifor O., MacLeod R.J., Diaz R., Bai M., Yamaguchi T., Yao T., Kifor I., Brown E.M. Regulation of MAP kinase by calcium-sensing receptor in bovine parathyroid and CaR-transfected HEK293 cells. Am. J. Physiol. Renal. Physiol. 280:2001;F291-F302.
7. 2+-sensing receptor (CaR) activates phospholipases C, A2, and D in bovine parathyroid and CaR-transfected, human embryonic kidney (HEK293) cells. J. Bone Miner. Res. 12:1997;715-725.
8. ′ -adenosine monophosphate accumulation by stimulating a pertussis toxin-sensitive guanine nucleotide-binding protein in cultured bovine parathyroid cells Endocrinology. 124:1989;233-239.
9. 2+ (polyvalent cation)-sensing receptor in rat pancreas. J. Biol. Chem. 274:1999;20561-20568.
10. Miedlich S., Gama L., Breitwieser G.E. Calcium sensing receptor activation by a calcimimetic suggests a link between cooperativity and intracellular calcium oscillations. J. Biol. Chem. 277:2002;49691-49699.
11. Brown E.M. Physiology and pathophysiology of the extracellular calcium-sensing receptor. Am. J. Med. 106:1999;238-253.
12. 2+(cation)-sensing receptor(s): one or many? Cell Calcium. 26:1999;77-83.
13. Nemeth E.F., Fox J. Calcimimetic compounds: a direct approach to controlling plasma levels of parathyroid hormone in hyperparathyroidism. Trends Endocrinol. Metab. 10:1999;66-71.
14. Quarles L.D. Cation sensing receptors in bone: a novel paradigm for regulating bone remodeling? J. Bone Miner. Res. 12:1997;1971-1974.
15. 2+ receptor-stimulated hormone release from sheep thyroid parafollicular cells. J. Physiol. 502:1997;31-44.
16. Crooke S.T. Molecular mechanisms of action of antisense drugs. Biochim. Biophys. Acta. 1489:1999;31-44.
17. Tu C., Chang W., Bikle D. The extracellular calcium-sensing receptor is required for calcium-induced differentiation in human keratinocytes. J. Biol. Chem. 276:2001;41079-41085.
18. 2+. Am. J. Physiol. Renal. Physiol. 280:2001;F868-F878.
19. 2+ activation of the human calcium sensing receptor. J. Biol. Chem. 273:1998;29712-29718.
20. Chang W., Pratt S., Chen T.H., Nemeth E., Huang Z., Shoback D. Coupling of calcium receptors to inositol phosphate and cyclic AMP generation in mammalian cells and Xenopus laevis oocytes and immunodetection of receptor protein by region-specific antipeptide antisera. J. Bone Miner. Res. 13:1998;570-580.
21. Ward D.T., McLarnon S.J., Riccardi D. Aminoglycosides increase intracellular calcium levels and ERK activity in proximal tubular OK cells expressing the extracellular calcium-sensing receptor. J. Am. Soc. Nephrol. 13:2002;1481-1489.
22. van de Put F.H., Elliott A.C. Imaging of intracellular calcium stores in individual permeabilized pancreatic acinar cells. Apparent homogeneous cellular distribution of inositol 1,4,5-trisphosphate-sensitive stores in permeabilized pancreatic acinar cells. J. Biol. Chem. 271:1996;4999-5006.
23. Prince R.J., Sine S.M. Molecular dissection of subunit interfaces in the acetylcholine receptor. Identification of residues that determine agonist selectivity. J. Biol. Chem. 271:1996;25770-25777.
24. Ward D.T., Brown E.M., Harris H.W. Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro. J. Biol. Chem. 273:1998;14476-14483.
25. Au S., Weiner N.D., Schacht J. Aminoglycoside antibiotics preferentially increase permeability in phosphoinositide-containing membranes: a study with carboxyfluorescein in liposomes. Biochim. Biophys. Acta. 902:1987;80-86.
26. Mingeot-Leclercq M.P., Brasseur R., Schanck A. Molecular parameters involved in aminoglycoside nephrotoxicity. J. Toxicol. Environ. Health. 44:1995;263-300.
27. 2+ oscillations. Biochem. J. 370:2003;695-702.
28. Beedle A.M., Hamid J., Zamponi G.W. Inhibition of transiently expressed low- and high-voltage-activated calcium channels by trivalent metal cations. J. Membr. Biol. 187:2002;225-238.
29. Urena P., Frazao J.M. Calcimimetic agents: review and perspectives. Kidney Int. Suppl. 85:2003;91-96.
30. Gowen M., Stroup G.B., Dodds R.A., James I.E., Votta B.J., Smith B.R., Bhatnagar P.K., Lago A.M., Callahan J.F., DelMar E.G., Miller M.A., Nemeth E.F., Fox J. Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats. J. Clin. Invest. 105:2000;1595-1604.