The conversion of thyroxine to triidothyronine in the lung: Comparison of activity of type I iodothyronine 5′ deiodinase in lung cancer with peripheral lung tissues

Monaldi Archives for Chest Disease - Pulmonary Series

Volumn 59, Issue 2, 2003, Pages 140-145

  Wawrzynska, L ^a   Sakowicz, A ^a   Rudzinski, P ^a   Langfort, R ^a   Kurzyna, M ^a  

^a NATIONAL TUBERCULOSIS AND LUNG DISEASES RESEARCH INSTITUTE   (Poland)

Author keywords

Iodothyronine 5 deiodinases; Lung cancer; Lung metabolism

Indexed keywords

IODINE 125; LIOTHYRONINE; PROTEIN; THYROTROPIN; THYROXINE; THYROXINE DEIODINASE; TYPE 1 THYROXINE DEIODINASE; TYPE 2 THYROXINE DEIODINASE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER GRADING; CANCER GROWTH; CANCER TISSUE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME LOCALIZATION; FEMALE; HUMAN; HUMAN TISSUE; ISOTOPE LABELING; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG PARENCHYMA; LUNG SQUAMOUS CELL CARCINOMA; MALE; PROTEIN CONTENT; STATISTICAL SIGNIFICANCE; THORACOTOMY; THYROID HORMONE METABOLISM; THYROID HORMONE RELEASE; THYROTROPIN BLOOD LEVEL;

EID: 0242574306     PISSN: 11220643     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Aw TY, Jones DP. Intracellular respiration in the lung. In: Crystal RG, West JB, Weibel ER, Barnes PJ. The Lung. Raven Press, Ltd, N. York, 1991; 1445-1453.
2. Ballard PL ed. Hormones and Lung Maturation. Springer Verl. Berlin, 1986, 28, 197-235.
3. Larsen PR. Thyroid hormone transport, cellular uptake, metabolism and hormone action. In: The Thyroid and Its Diseases, LJ DeGroot, PR Larsen and G Hennemann, eds, Churchill Livingstone, Inc. New York,
4. Itagaki YK, Yoshida H, Ikede K, Kaise N, Yamamoto M, Sakurada T, Yoshinaga K. Thyroxine 5′deiodinase in human anterior pituarity tumors. J Clin Endocrinol Metab 1990; 71: 340-344.
5. Jakobs TC, Koehler MR, Schmutzler C, Glaser F, Schmid M, Kohrle J. Structure of the human type I 5′deiodinase gene and localisation to chromosome 1p32-p33. Genomics 1997; 42: 361-363.
6. Ohba K, Yoshioka T, Muraki T. Identification of two novel splicing variants of human type II iodothyronine deiodinase mRNA. Mol Cell Endocrinol 2001; 172 (1-2): 169-175.
7. Kohrle J. Biochemistry of iodothyronine deiodination. Importance of pH and regulatory iodothyronines. In: Low T3 Syndrome, R Hesch ed, Academic Press London and New York 1981, 61-70.
8. Ramadurai SM, Nielsen HC, Chen Y, Hatzis D, Sosenko IR. Differential effects in vivo of thyroid hormone on the expression of surfactant phospholipids, surfactant protein mRNA and antioxidant enzyme mRNA in fetal rat lung. Exp Lung Res 1998; 24: 641-657.
9. Yu J, Koenig RJ. Regulation of hepatocyte thyroxine 5′-deiodinase by T3 and nuclear receptor coactivators as a model of the sick euthyroid syndrome. J Biol Chem 2000; 275: 38296-38301.
10. Wawrzynska L, Sakowicz A, Filipecki S. Euthyroid sick syndrome (ess) in patients with respiratory failure. Pneumonol Alergol Pol 1996; 64 (suppl 2): 193-199.
11. Palazzo MG, Sutter PM. Delivery dependent oxygen consumption in patients with septic shock: Daily variations, relationship with outcome and the sick - Euthyroid syndrome. Intensive Care Med 1991; 17: 325-332.
12. Wawrzynska L, Caban P, Rudzinski P. Estimation of the conversion of the thyroxine to triiodothyronine in lung (preliminary report). Pneumonol Alergol Pol 1996; 64 (suppl 2): 200-206.
13. Silva JE, Leonard JL, Crantz FR, Larsen PR. Evidence for two tissue - Specific pathways for in vivo thyroxine 5′deiodination in the rat. J Clin Invest 1982;69:1176-1184.
14. Escobar-Morreale HF, Obregon MJ, Hernandez A, Escobar del Rey F, Morreale de Escobar G. Regulation of iodothyronine deiodinase activity as studied in thyroidectomized rats infused with thyroxine or triiodothyronine. Endocrinology 1997; 138: 2559-2568.
15. Kohrle J. Thyroid hormone deiodination in target tissues - A regulatory role for the trace element selenium? Exp Clin Endocrinol 1994; 102: 63-89.
16. Leonard JL. Identification and structure analysis of iodothyronine deiodinases. In: Greer MA ed, The Thyroid Gland, Raven Press, New York, 1991; 285-321.
17. Safran M, Leonard JL. Comparison of the physicochemical properties of type I and type II iodothyronine 5′deiodinase. J Biol Chem 1991; 266: 3233-3238.
18. Silva JE, Larsen PR. Potential of brown adipose tissue type II thyroxine 5′deiodinase as a local systemic source of triiodothyronine in rats. J Clin Invest 1985; 76: 2296-2305.
19. Salvatore D, Tu H, Harney JW, Larsen PR. Type II iodothyronine Deiodinase is highly expressed in human thyroid. J Clin Invest 1996; 98: 962-968.
20. Escobar-Morreale HF, Obregon MJ, Escobar del Rey F, Morreale de Escobar G. Tissue - Specific patterns of changes in 3,5,3′-triiodothyronine concentrations in thyroidectomized rats infused with increasing doses of the hormone. Which are the regulatory mechanisms? Biochimie 1999; 81: 453-462.
21. Leonard JL, Rosenberg IN. Iodothyronine 5′Deiodinase from rat kidney: Substrace specificity and the 5′Deiodination or reverse Triiodothyronine. Endocrinology 1980; 107: 1376-1383.
22. Nauman A, Ambroziak M, Pachucki J, Puzianowska-Kuznicka M, Nauman J. Effect of gold (Au+) on 5′-deiodination of iodothyronines in human thyroid, liver, kidney and adipose tissue. Endokrynol Pol - Polish. J Endocrinol 1999; 50: 239-248.
23. Curcio C, Baqui MM, Salvatore D, Rihn BH, Mohr S, Harney JW, Larsen PR, Bianco AC. The human type 2 iodothyronine deiodinase is a selenoprotein highly expressed in a mesothelioma cell line. J Biol Chem 2001.