Identification of two novel splicing variants of human type II iodothyronine deiodinase mRNA

Molecular and Cellular Endocrinology

Volumn 172, Issue 1-2, 2001, Pages 169-175

  Ohba, Ken ichi ^a   Yoshioka, Toshimasa ^a   Muraki, Takamura ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Alternative splicing; Reverse transcription polymerase chain reaction (RT PCR); Selenocysteine; Thyroid hormone; Type II iodothyronine deiodinase (DII)

Indexed keywords

3,3',5' TRIIODOTHYRONINE; DNA FRAGMENT; ISOENZYME; MESSENGER RNA; RNA; SELENOCYSTEINE; SELENOPROTEIN; THYROXINE; THYROXINE DEIODINASE; THYROXINE DEIODINASE 2; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ARTICLE; BRAIN; CATALYSIS; CELL LINE; CODON; CONSENSUS SEQUENCE; CONTROLLED STUDY; DEIODINATION; ENDOTHELIUM CELL; EXON; FRAMESHIFT MUTATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE INSERTION SEQUENCE; GENETIC PROCEDURES; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRON; KIDNEY; LUNG; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN FAMILY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; STOP CODON; TISSUE DISTRIBUTION; TRACHEA; UMBILICAL VEIN;

ALTERNATIVE SPLICING; BASE SEQUENCE; CELL LINE; CLONING, MOLECULAR; ENDOTHELIUM, VASCULAR; EXONS; HUMANS; IODIDE PEROXIDASE; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ALIGNMENT; TISSUE DISTRIBUTION; VARIATION (GENETICS);

EID: 0035857454     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(00)00368-3     Document Type: Article

References (24)

1. Characterization of the 5′-flanking and 5′-untranslated regions of the cyclic adenosine 3′,5′-monophosphate-responsive human type 2 iodothyronine deiodinase gene
2. Type I iodothyronine deiodinase is a selenocysteine-containing enzyme
3. Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3′ untranslated region
4. Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons
5. The 3′-untranslated region of human type 2 iodothyronine deiodinase mRNA contains a functional selenocysteine insertion sequence element
6. Genomic characterization of the coding region of the human type II 5'-deiodinase gene
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